İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri

Serap Berktaş, (Erciyes Üniversitesi, Mühendislik Fakültesi, Gıda Mühendisliği Bölümü, Kayseri, Türkiye)
Mustafa Çam (Erciyes Üniversitesi, Mühendislik Fakültesi, Gıda Mühendisliği Bölümü, Kayseri, Türkiye)
Akademik Gıda
18 6
Yıl: 2020 Cilt: 18 Sayı: 3 Sayfa Aralığı: 270 - 278 Metin Dili: Türkçe DOI: 10.24323/akademik-gida.818125 İndeks Tarihi: 16-11-2021

İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri

Öz:
Bu çalışma Elaeagnus angustifolia L. (iğde) meyve ve yapraklarının antioksidan ve antidiyabetik etkilerini belirlemekve karşılaştırmak için gerçekleştirilmiştir. Metanol:su (1:1, v/v) ile yapılan iğde meyve ve yaprak ekstraktlarının toplamfenolik, toplam flavonoid ve tanen içerikleri, antioksidan aktiviteleri (DPPH ve ABTS metotları) ve α-glukozidaz ve αamilaz enzimlerini inhibe edici etkileri araştırılmıştır. Ayrıca ekstraktlarda lipaz inhibisyonu aktivitesi tayini degerçekleştirilmiştir. İğde meyve ve yapraklarının α-glukozidaz enzimini %50 oranında inhibe ettikleri değerler (IC50)sırasıyla 17.11 μg/mL ve 124.7 μg/mL olarak tespit edilirken, α-amilaz enzimini sadece meyvenin inhibe etttiği (21.95mg/mL) ve hem meyve hem de yaprakların lipaz inhibisyon aktivitesi göstermediği belirlenmiştir. Meyve ve yapraklarınekstraktlarının toplam fenolik, flavonoid ve tanen içerikleri ile antioksidan aktivite değerleri incelendiğinde meyveninbiyoaktif içeriğinin yaprağına göre anlamlı şekilde yüksek olduğu tespit edilmiştir (p<0.05). İğdenin meyve veyapraklarının içerdiği biyoaktif bileşikler sayesinde göstermiş olduğu antidiyabetik aktivitenin in vitro çalışmalar sonrasıelde edildiği göz önüne alındığında, iğdenin özellikle de meyve kısmının tip 2 diyabet rahatsızlıklarının doğal yoldantedavisinde destekleyici yönünün olabileceği belirlenmiştir.
Anahtar Kelime:

Antioxidant and Antidiabetic Properties of Oleaster (Elaeagnus angustifolia L.) Fruits and Leaves

Öz:
This study was carried out to determine the antioxidant and antidiabetic activities of Elaeagnus angustifolia L. (oleaster) fruits and leaves. The total phenolic, total flavonoid and tannin contents, antioxidant activities (DPPH and ABTS methods), and inhibitory effects against α-glucosidase and α-amylase enzyme were investigated in the oleaster fruit and leaf extracts obtained with methanol:water (1:1, v/v). In addition, lipase inhibition activity was determined in these extracts. The values in which the fruit and leaves of oleaster inhibit the α-glucosidase enzyme by 50% (IC50) were determined as 17.11 μg/mL and 124.71 μg/L, respectively. Neither fruits nor leaves displayed a lipase inhibition activity. In terms of the phenolic, flavonoid and tannin contents and antioxidant activity values of the extracts of fruits and leaves, the bioactive content of fruits was significantly higher than that of leaves (p<0.05). Considering in vitro antidiabetic activities of the fruits and leaves of oleaster, the consumption of these natural extracts may have a potential for the treatment of type 2 diabetes.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Berktaş S, Çam M (2020). İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. , 270 - 278. 10.24323/akademik-gida.818125
Chicago Berktaş Serap,Çam Mustafa İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. (2020): 270 - 278. 10.24323/akademik-gida.818125
MLA Berktaş Serap,Çam Mustafa İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. , 2020, ss.270 - 278. 10.24323/akademik-gida.818125
AMA Berktaş S,Çam M İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. . 2020; 270 - 278. 10.24323/akademik-gida.818125
Vancouver Berktaş S,Çam M İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. . 2020; 270 - 278. 10.24323/akademik-gida.818125
IEEE Berktaş S,Çam M "İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri." , ss.270 - 278, 2020. 10.24323/akademik-gida.818125
ISNAD Berktaş, Serap - Çam, Mustafa. "İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri". (2020), 270-278. https://doi.org/10.24323/akademik-gida.818125
APA Berktaş S, Çam M (2020). İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. Akademik Gıda, 18(3), 270 - 278. 10.24323/akademik-gida.818125
Chicago Berktaş Serap,Çam Mustafa İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. Akademik Gıda 18, no.3 (2020): 270 - 278. 10.24323/akademik-gida.818125
MLA Berktaş Serap,Çam Mustafa İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. Akademik Gıda, vol.18, no.3, 2020, ss.270 - 278. 10.24323/akademik-gida.818125
AMA Berktaş S,Çam M İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. Akademik Gıda. 2020; 18(3): 270 - 278. 10.24323/akademik-gida.818125
Vancouver Berktaş S,Çam M İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri. Akademik Gıda. 2020; 18(3): 270 - 278. 10.24323/akademik-gida.818125
IEEE Berktaş S,Çam M "İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri." Akademik Gıda, 18, ss.270 - 278, 2020. 10.24323/akademik-gida.818125
ISNAD Berktaş, Serap - Çam, Mustafa. "İğde (Elaeagnus angustifolia L.) Meyve ve Yapraklarının Antioksidan ve Antidiyabetik Özellikleri". Akademik Gıda 18/3 (2020), 270-278. https://doi.org/10.24323/akademik-gida.818125
Sayfa Oluşturulma Tarihi
23-04-2024 20:7

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