TY  - JOUR
TI  - THE EXAMINATION OF THE EFFECTS OF PPAR-A (RS4253778) ON SERUMLIPIDS IN ELITE CROSS-COUNTRY SKIERS
AB  - The purpose of this study was to examine the effects of PPAR-a (rs4253778) on serum lipids in elite crosscountry skiers. This study included 34 cross-country skiers (23 males and 11 females who participated in the Turkish skiing national team camp). Genotyping for the PPAR-a gene rs4253778 G/C polymorphism was performed by PCR on Tercyk multicanal amplificator and restriction enzyme digestion. Statistical analysis was done by using the SPSS 22.0 package program. Genotypic frequency of the PPAR-a polymorphism was detected in cross-country skiers. PPAR-a GG, GC and CC genotypes were detected as 67.64%, 23.52% and 8.82%, respectively in 34 cross-country skiers while PPAR-a GG, GC and CC genotypes were detected as 47.05%, 16.64%, and 2.94%, respectively in elite males. PPAR-a GG, GC and CC genotypes were detected as 20.58 %, 5.88%, and 5.88%, respectively in females. PPAR-a G and C allele were detected as 49 and 19, respectively in 34 elite endurance athletes. In the present study, the GG genotypes were detected at higher frequencies in elite athletes (67.64% respectively) than GC and CC (23.52% and 8.82%, respectively). The difference between the PPAR-a G/C gene polymorphism of Turkish elite cross-country skiers and serum total cholesterol, HDLcholesterol, LDL- cholesterol and TG levels was not statistically significant. Although there was not any statistically significant difference between the PPAR-a G/C gene polymorphism and lipid profiles of Turkish elite cross-country skiers, it is foreseen that PPAR-α genes have an important effect on endurance performance in sports requiring endurance such as cross-country skiing.
AU  - Ulucan, Korkut
AU  - sercan dogan, canan
AU  - Bilici, Muhammed fatih
AU  - kaynar, ömer
DO  - 10.17155/omuspd.684940
PY  - 2021
JO  - Spor ve Performans Araştırmaları Dergisi
VL  - 12
IS  - 1
SN  - 1309-5110
SP  - 72
EP  - 79
DB  - TRDizin
UR  - http://search/yayin/detay/462416
ER  -