The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits
Yıl: 2021 Cilt: 27 Sayı: 4 Sayfa Aralığı: 425 - 429 Metin Dili: İngilizce DOI: 10.9775/kvfd.2021.25402 İndeks Tarihi: 22-11-2021
The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits
Öz: This study was aimed to compare the eff ect of 1% atropine, 1% cyclopentolate, 0.5% tropicamide, and 10% phenylephrine eye drops onintraocular pressure (IOP) and central corneal thickness (CCT) in New Zealand White rabbits. Adult male, eight, New Zealand White rabbits wererandomly received each of four mydriatic eye drops separately on left eye at a one-week washout period. Each rabbit received all of five diff erenttreatments (sterile saline solution, four mydriatic drugs) on the left eye, whereas no measurements were performed on the right eyes during theexperiment. The IOP and CCT recordings of rabbits were performed until the pupil returned to normal diameter. The mean CCT values of sterilesaline, 1% atropine, 0.5% tropicamide, 1% cyclopentolate, and 10% phenylephrine were 370±15, 368±17, 372±15, 364±18, and 360±17 µm,respectively, and no statistically significant diff erences (P>0.05) were observed among groups. The mean IOP values of control (sterile saline), 1%atropine, 0.5% tropicamide, 1% cyclopentolate, and 10% phenylephrine as, 9.7±2.1, 10.4±1.8, 10.3±2.1, 11.0±2.1, and 10±1.8 mmHg, respectively,and these were not statistically significant among groups (P>0.05). In conclusion, topical 1% atropine, 0.5% tropicamide 1% cyclopentolate, and10% phenylephrine do not have significantly eff ect on IOP and CCT in New Zealand white rabbits.
Anahtar Kelime: Beyaz Yeni Zelanda Tavşanlarında Farklı Midriyatiklerin Göz İçi Basıncı ve Merkezi Kornea Kalınlığı Üzerine Etkileri
Öz: Bu çalışma, Beyaz Yeni Zelanda tavşanlarında %1 atropin, %1 siklopentolat, %0.5 tropikamid ve %10 fenilefrin göz damlasının göz içi basıncı (GİB) ve merkezi kornea kalınlığı (MKK) üzerindeki etkilerini karşılaştırmayı amaçladı. Sekiz, yetişkin erkek Beyaz Yeni Zelanda tavşanının sol gözüne dört ayrı midriyatik göz damlası bir haftalık arınma periyoduyla rastgele uygulandı. Her tavşanın sol gözüne beş farklı tedavinin (steril serum fizyolojik, dört midriyatik ilaç) tamamı uygulanırken, sağ gözlerde ise deney boyunca ölçüm yapılmadı. Tavşanların GİB ve MKK verileri pupil normal çapa dönene kadar alındı. Steril salin, %1 atropin, %0.5 tropikamid, %1 siklopentolat ve %10 fenilefrinin ortalama MKK değerleri sırasıyla 370±15, 368±17, 372±15, 364±18 ve 360±17 µm idi ve gruplar arasında istatistiksel olarak anlamlı farklılık (P>0.05) gözlenmedi. Kontrol (steril salin), %1 atropin, %0.5 tropikamid, %1 siklopentolat ve %10 fenilefrinin ortalama GİB değerleri sırasıyla 9.7±2.1, 10.4±1.8, 10.3±2.1, 11.0±2.1 ve 10±1.8 mmHg’idi ve gruplar arasında istatistiksel olarak önem yoktu (P>0.05). Sonuç olarak, Beyaz Yeni Zelanda tavşanlarında topikal %1 atropin, %0.5 tropikamid, %1 siklopentolat ve %10 fenilefrinin GİB ve MKK üzerinde anlamlı bir etkisi yoktur.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Yanmaz L, Okur S, Ersöz U, SENOCAK M, Doğan E, Okumus Z (2021). The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. , 425 - 429. 10.9775/kvfd.2021.25402 |
| Chicago | Yanmaz Latif Emrah,Okur Sıtkıcan,Ersöz Uğur,SENOCAK MÜMIN GOKHAN,Doğan Elif,Okumus Zafer The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. (2021): 425 - 429. 10.9775/kvfd.2021.25402 |
| MLA | Yanmaz Latif Emrah,Okur Sıtkıcan,Ersöz Uğur,SENOCAK MÜMIN GOKHAN,Doğan Elif,Okumus Zafer The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. , 2021, ss.425 - 429. 10.9775/kvfd.2021.25402 |
| AMA | Yanmaz L,Okur S,Ersöz U,SENOCAK M,Doğan E,Okumus Z The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. . 2021; 425 - 429. 10.9775/kvfd.2021.25402 |
| Vancouver | Yanmaz L,Okur S,Ersöz U,SENOCAK M,Doğan E,Okumus Z The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. . 2021; 425 - 429. 10.9775/kvfd.2021.25402 |
| IEEE | Yanmaz L,Okur S,Ersöz U,SENOCAK M,Doğan E,Okumus Z "The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits." , ss.425 - 429, 2021. 10.9775/kvfd.2021.25402 |
| ISNAD | Yanmaz, Latif Emrah vd. "The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits". (2021), 425-429. https://doi.org/10.9775/kvfd.2021.25402 |
| APA | Yanmaz L, Okur S, Ersöz U, SENOCAK M, Doğan E, Okumus Z (2021). The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 27(4), 425 - 429. 10.9775/kvfd.2021.25402 |
| Chicago | Yanmaz Latif Emrah,Okur Sıtkıcan,Ersöz Uğur,SENOCAK MÜMIN GOKHAN,Doğan Elif,Okumus Zafer The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 27, no.4 (2021): 425 - 429. 10.9775/kvfd.2021.25402 |
| MLA | Yanmaz Latif Emrah,Okur Sıtkıcan,Ersöz Uğur,SENOCAK MÜMIN GOKHAN,Doğan Elif,Okumus Zafer The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, vol.27, no.4, 2021, ss.425 - 429. 10.9775/kvfd.2021.25402 |
| AMA | Yanmaz L,Okur S,Ersöz U,SENOCAK M,Doğan E,Okumus Z The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2021; 27(4): 425 - 429. 10.9775/kvfd.2021.25402 |
| Vancouver | Yanmaz L,Okur S,Ersöz U,SENOCAK M,Doğan E,Okumus Z The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits. Kafkas Üniversitesi Veteriner Fakültesi Dergisi. 2021; 27(4): 425 - 429. 10.9775/kvfd.2021.25402 |
| IEEE | Yanmaz L,Okur S,Ersöz U,SENOCAK M,Doğan E,Okumus Z "The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits." Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 27, ss.425 - 429, 2021. 10.9775/kvfd.2021.25402 |
| ISNAD | Yanmaz, Latif Emrah vd. "The Eff ects of Diff erent Mydriatics on Intraocular Pressure and Central Corneal Thickness in New Zealand White Rabbits". Kafkas Üniversitesi Veteriner Fakültesi Dergisi 27/4 (2021), 425-429. https://doi.org/10.9775/kvfd.2021.25402 |
