Groundwater is a major drinking water resource in arid coastal regions. The groundwater quality of Bosaso city experienced degradation due to rapid urbanization and industrialization. This study was carried out to delineate the spatial distribution of groundwater quality parameters and evaluate groundwater suitability for drinking and irrigation uses. The groundwater samples were collected from Bosaso Plain to determine the pH, electrical conductivity (EC), total dissolved solids (TDS), and sodium and chloride concentrations. To categorize water quality for irrigation purposes, sodium adsorption ratio (SAR) was calculated. Ordinary kriging procedure was performed in order to map the spatial distribution of groundwater quality parameters. The interpretation of laboratory analysis results revealed that the most of groundwater wells in the study area is unsafe for drinking purposes due to high salinity, except for the central area (Biyo Kulule). In terms of irrigation uses, the minor area may be under the risk of alkalinity or sodium hazard. However, all groundwater supply points are not suitable for irrigation due to the salinization risk and can be only used to irrigate high salt-tolerant crops. The final maps show that the groundwater quality decreases from southeast to the north of the plain. This indicates that the groundwater is probably subjected to the seawater intrusion. In this regard, the implementation of a groundwater monitoring program is necessary to achieve concrete results. Nevertheless, the most suitable groundwater quality is found to be at the central part of the Bosaso plain.