Objective: Premature Ejaculation is the most commonsexual dysfunction in men. Although the pathophysiolo gy has not been clarified yet, psychological factors havebeen studied frequently. It may be useful to investigatethe temperament and character characteristics of thepatients in understanding the premature ejaculation,which has both biological and psychological dimensions.Neuroticism and harm avoidance dimensions are foundto be associated with sexual dysfunction. In this study,temperament, character, sexual satisfaction, anxiety anddepression levels of lifelong and acquired prematureejaculation patients are investigated. Method: Fortypatients diagnosed with premature ejaculation and 40controls were included in the study. The patient groupwas divided into two groups as lifelong (n= 20) andacquired (n= 20) subtypes. Sociodemographic dataform, Temperament and Character Inventory, Golombok Rust Sexual Satisfaction Scale, Hospital Anxiety andDepression Scale are applied. Results: Premature ejacu lation patients had lower sexual satisfaction scores andhigher fatigability sub-dimension scores of harm avoid ance, comparing to the control group (p< 0.05).Discussion: Harm avoidance as a temperament feature,is associated with neurotransmitter structures, is aprominent parameter in sexual dysfunctions. Largersampling and longitudinal studies are needed to investi gate the relationship between sexual dysfunctions andharm avoidance.