TY  - JOUR
TI  - Ischemia modified albumin: A potentialmarker for global metabolic risk in genera lized anxiety disorder and panic disorder
AB  - Objective: Ischemia modified albumin (IMA) is analtered type of albumin produced due to exposure tohypoxia, acidosis, inflammation, or oxidative stress. Inthis study, we aimed to evaluate the serum IMA levels innewly diagnosed and medication-naive generalized an xiety disorder (GAD) and panic disorder (PD) patients.Method: This cross-sectional study included medication naive 23 GAD, 25 PD patients, and 28 healthy controls.The participants were evaluated with a sociodemograp hic form, the Beck Depression Inventory (BDI), and theBeck Anxiety Inventory (BAI). Venous blood sampleswere collected from all participants, and IMA levels androutine biochemical parameters were measured.Results: There was no statistically significant differencebetween three groups in terms of age, gender, bodymass index (BMI) and routine biochemical markers of theparticipants (p>0.05). The GAD and PD groups had sig nificantly higher serum IMA levels than healthy controls(p<0.01), whereas there was no statistically significantdifference in IMA levels between GAD and PD groups(p=0.994). Additionally, correlation analysis showed apositive correlation between IMA levels with BDI and BAIscores (r=0.449 and r=0.632, respectively,p<0.001).Discussion: Higher IMA levels in patients withGAD and PD may indicate metabolic stress on thesepatients. Anxiety disorders may tend to various bioche mical disturbances, and IMA could be an important newmarker that indicates global metabolic risk in suchpatients. This research is the first study that evaluatesIMA levels in anxiety disorders.
AU  - Kabadayi Sahin, Esra
AU  - Turan, Gökçen
AU  - NEŞELİOĞLU, Salim
AU  - Atagün, Murat İlhan
DO  - 10.5505/kpd.2020.49404
PY  - 2021
JO  - Klinik Psikiyatri Dergisi
VL  - 24
IS  - 2
SN  - 1302-0099
SP  - 153
EP  - 159
DB  - TRDizin
UR  - http://search/yayin/detay/467159
ER  -