Yıl: 2021 Cilt: 46 Sayı: 4 Sayfa Aralığı: 1733 - 1735 Metin Dili: İngilizce DOI: 10.17826/cumj.985225 İndeks Tarihi: 29-07-2022

A case of premature infant who developed tissue necrosis after propofol infusion

Öz:
To the Editor, Propofol is one of the most widely used drugs as an anesthetic agent due to its ideal chemical properties, neutral pH level and isotonicity. Tissue damage due to propofol is extremely rare1 . There are publications in the literature reporting that areas of necrosis develop secondary to infections2,3. Propofol-related necrosis, seizures and thrombosis are rarely seen in newborns and infancy4 . Here, we present a case of a premature baby with inferior vena cava thrombus, seizures and areas of necrosis in the right leg due to propofol administered during anesthesia in inguinal hernia surgery. To the best of our knowledge, the infant was the youngest patient in the literature to suffer thrombosis after administration of propofol.
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  • 2. Veber B, Gachot B, Bedos JP, Wolff M. Severe sepsis after intravenous injection of contaminated propofol (letter). Anesthesiology 1994; 80: 712–3.
  • 3. Sakuragi T, Yanagisawa K, Shirai Y, Dan K. Growth of Escherichia coli in propofol, lidocaine, and mixtures of propofol and lidocaine. Acta Anaesthesiol Scand 1999; 43: 476–9.
  • 4. Roth W, Eschertzhuber S, Gardetto A, Keller C. Extravasation of propofol is associated with tissue necrosis in small children. Paediatr Anaesth 2006; 16: 887–9.
  • 5. Wachowski I, Jolly DT, Hrazdil J, Galbraith JC, Greacen M, Clanachan AS. The growth of microorganisms in propofol and mixtures of propofol and lidocaine. Anesth Analg 1999; 88: 209–12.
  • 6. Reddy KR, Chandramouli BA, Rao GS. Acute venous thrombosis caused by lipid-free propofol. Anaesthesia 2006; 61: 300–1.
  • 7. Finley GA, MacManus B, Sampson SE, Fernan-dez CV, Retallick R. Delayed seizures following sedation with propofol. Can J Anaesth 1993; 40: 863–5.
  • 8. Hickey KS1, Martin DF, Chuidian FX. Propofol-induced seizure-like phenomena. J Emerg Med 2005; 29: 447–9.
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APA Hamitoglu S, Satar M (2021). A case of premature infant who developed tissue necrosis after propofol infusion. , 1733 - 1735. 10.17826/cumj.985225
Chicago Hamitoglu Serif,Satar Mehmet A case of premature infant who developed tissue necrosis after propofol infusion. (2021): 1733 - 1735. 10.17826/cumj.985225
MLA Hamitoglu Serif,Satar Mehmet A case of premature infant who developed tissue necrosis after propofol infusion. , 2021, ss.1733 - 1735. 10.17826/cumj.985225
AMA Hamitoglu S,Satar M A case of premature infant who developed tissue necrosis after propofol infusion. . 2021; 1733 - 1735. 10.17826/cumj.985225
Vancouver Hamitoglu S,Satar M A case of premature infant who developed tissue necrosis after propofol infusion. . 2021; 1733 - 1735. 10.17826/cumj.985225
IEEE Hamitoglu S,Satar M "A case of premature infant who developed tissue necrosis after propofol infusion." , ss.1733 - 1735, 2021. 10.17826/cumj.985225
ISNAD Hamitoglu, Serif - Satar, Mehmet. "A case of premature infant who developed tissue necrosis after propofol infusion". (2021), 1733-1735. https://doi.org/10.17826/cumj.985225
APA Hamitoglu S, Satar M (2021). A case of premature infant who developed tissue necrosis after propofol infusion. Cukurova Medical Journal, 46(4), 1733 - 1735. 10.17826/cumj.985225
Chicago Hamitoglu Serif,Satar Mehmet A case of premature infant who developed tissue necrosis after propofol infusion. Cukurova Medical Journal 46, no.4 (2021): 1733 - 1735. 10.17826/cumj.985225
MLA Hamitoglu Serif,Satar Mehmet A case of premature infant who developed tissue necrosis after propofol infusion. Cukurova Medical Journal, vol.46, no.4, 2021, ss.1733 - 1735. 10.17826/cumj.985225
AMA Hamitoglu S,Satar M A case of premature infant who developed tissue necrosis after propofol infusion. Cukurova Medical Journal. 2021; 46(4): 1733 - 1735. 10.17826/cumj.985225
Vancouver Hamitoglu S,Satar M A case of premature infant who developed tissue necrosis after propofol infusion. Cukurova Medical Journal. 2021; 46(4): 1733 - 1735. 10.17826/cumj.985225
IEEE Hamitoglu S,Satar M "A case of premature infant who developed tissue necrosis after propofol infusion." Cukurova Medical Journal, 46, ss.1733 - 1735, 2021. 10.17826/cumj.985225
ISNAD Hamitoglu, Serif - Satar, Mehmet. "A case of premature infant who developed tissue necrosis after propofol infusion". Cukurova Medical Journal 46/4 (2021), 1733-1735. https://doi.org/10.17826/cumj.985225