The gestation period of rats is on average 21 to 23 days. Conceptus can be detected by ultrasonography after the8‐9th days of the pregnancy. The total number of fetuses per pregnancy is 1 to 20. In some cases, abortion occursdepending on many etiological factors, and it is the most common complication of pregnancy. The subject of the presentcase report was the surgical management of spontaneous abortion using inhalation anesthesia in a rat. The material of thecase report was a female albino 2‐year‐ old rat weighing about 450 gr. The rat was admitted with vaginal bleeding andabortion in to the clinic. In anamnesis, it was reported that a pup was stillborn about three hours ago and then no otherpup was delivered. Furthermore, it was informed that there was ongoing vaginal bleeding since the last 4‐5 hours. Uponphysical examination and ultrasonography, the case was diagnosed as abortion. It was decided to intervene with theabortion by surgery. The rat was premedicated subcutaneously with atropine sulphate and general anesthesia was inducedwith isoflurane through inhalation. Then, celiotomy was performed at cauda umbilicus. In total, 13 non viable fetuses wereremoved from both uterine horns. Incision wounds were sutured and the rat was evenly awakened from anesthesia anddischarged. In conclusion, surgical management of the abortion case using inhalation anesthesia was successfullyperformed on the rat.