Yıl: 2021 Cilt: 32 Sayı: 3 Sayfa Aralığı: 792 - 797 Metin Dili: İngilizce DOI: 10.52312/jdrs.2021.12 İndeks Tarihi: 03-01-2022

Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone

Öz:
A five-year-old boy with Ewing sarcoma of the proximal femurwas operated at our institution with limb-sparing surgeryand biological reconstruction of the proximal femur with avascularized fibular autograft. During this procedure, theproximal femur was soaked in liquid nitrogen which wassubsequently fixed to the fibular autograft, while the epiphysisof the femoral head was spared. To the best of our knowledge,this is the first report of epiphysis-sparing surgery of theproximal femur via a vascularized fibular autograft surroundedby a liquid nitrogen-treated tumor bearing bone autograft.Three years postoperatively, the patient remains disease-free,has a full weight-bearing extremity with good function, anda remodeled proximal femur with minimal deformity. Thereare no radiological or clinical signs indicative of femoralhead osteonecrosis. In conclusion, hip-sparing biologicalreconstruction is a successful method of limb preservation asan alternative to tumor endoprostheses.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
  • 1. Yoshida Y, Osaka S, Tokuhashi Y. Analysis of limb function after various reconstruction methods according to tumor location following resection of pediatric malignant bone tumors. World J Surg Oncol 2010;8:39.
  • 2. Petersen MM, Hovgaard D, Elberg JJ, Rechnitzer C, Daugaard S, Muhic A. Vascularized fibula grafts for reconstruction of bone defects after resection of bone sarcomas. Sarcoma 2010;2010:524721.
  • 3. Manfrini M, Innocenti M, Ceruso M, Mercuri M. Original biological reconstruction of the hip in a 4-year-old girl. Lancet 2003;361:140-2.
  • 4. Capanna R, Bufalini C, Campanacci M. A new technique for reconstructions of large metadiaphyseal bone defects. Orthop Traumatol 1993;2:159-77.
  • 5. Seu MY, Haley A, Cho BH, Carl HM, Bos TJ, Hassanein AH, et al. Proximal femur reconstruction using a vascularized fibular epiphysis within a cadaveric femoral allograft in a child with Ewing sarcoma: A case report. Plastic and Aesthetic Research 2017;4:209-14.
  • 6. Houdek MT, Wagner ER, Stans AA, Shin AY, Bishop AT, Sim FH, et al. What is the outcome of allograft and intramedullary free fibula (Capanna technique) in pediatric and adolescent patients with bone tumors? Clin Orthop Relat Res 2016;474:660-8.
  • 7. Khattak MJ, Umer M, Haroon-ur-Rasheed, Umar M. Autoclaved tumor bone for reconstruction: An alternative in developing countries. Clin Orthop Relat Res 2006;447:138-44.
  • 8. Jeon DG, Kim MS, Cho WH, Song WS, Lee SY. Pasteurized autograft for intercalary reconstruction: An alternative to allograft. Clin Orthop Relat Res 2007;456:203-10.
  • 9. Kim JD, Lee GW, Chung SH. A reconstruction with extracorporeal irradiated autograft in osteosarcoma around the knee. J Surg Oncol 2011;104:187-91.
  • 10. Tsuchiya H, Wan SL, Sakayama K, Yamamoto N, Nishida H, Tomita K. Reconstruction using an autograft containing tumour treated by liquid nitrogen. J Bone Joint Surg [Br] 2005;87:218-25.
  • 11. Takata M, Sugimoto N, Yamamoto N, Shirai T, Hayashi K, Nishida H, et al. Activity of bone morphogenetic protein-7 after treatment at various temperatures: Freezing vs. pasteurization vs. allograft. Cryobiology 2011;63:235-9.
  • 12. Tanzawa Y, Tsuchiya H, Shirai T, Hayashi K, Yo Z, Tomita K. Histological examination of frozen autograft treated by liquid nitrogen removed after implantation. J Orthop Sci 2009;14:761-8.
  • 13. Moteki T, Yanagawa T, Saito K. Autograft treated with liquid nitrogen combined with the modified Masquelet technique for bone defect after resection of malignant bone tumors: Two case reports. J Orthop Sci 2019;24:573-7.
  • 14. van Kampen M, Grimer RJ, Carter SR, Tillman RM, Abudu A. Replacement of the hip in children with a tumor in the proximal part of the femur. J Bone Joint Surg [Am] 2008;90:785-95.
  • 15. Decilveo AP, Szczech BW, Topfer J, Wittig JC. Reconstruction using expandable endoprostheses for skeletally immature patients with sarcoma. Orthopedics 2017;40:e157-e163.
  • 16. Eckardt JJ, Safran MR, Eilber FR, Rosen G, Kabo JM. Expandable endoprosthetic reconstruction of the skeletally immature after malignant bone tumor resection. Clin Orthop Relat Res 1993;(297):188-202.
  • 17. Tsuda Y, Tsoi K, Stevenson JD, Fujiwara T, Tillman R, Abudu A. Extendable endoprostheses in skeletally immature patients: A study of 124 children surviving more than 10 years after resection of bone sarcomas. J Bone Joint Surg [Am] 2020;102:151-62.
  • 18. Aponte-Tinao LA, Albergo JI, Ayerza MA, Muscolo DL, Ing FM, Farfalli GL. What are the complications of allograft reconstructions for sarcoma resection in children younger than 10 years at long-term followup? Clin Orthop Relat Res 2018;476:548-55.
  • 19. Aiona M, Do KP, Emara K, Dorociak R, Pierce R. Gait patterns in children with limb length discrepancy. J Pediatr Orthop 2015;35:280-4.
  • 20. Rego P, Mascarenhas V, Collado D, Coelho A, Barbosa L, Ganz R. Arterial topographic anatomy near the femoral head-neck perforation with surgical relevance. J Bone Joint Surg [Am] 2017;99:1213-21.
  • 21. Atik OŞ. What are the expectations of an editor from a scientific article? Jt Dis Relat Surg 2020;31:597-8.
APA ayvaz m, Göker B, Leblebicioglu G (2021). Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. , 792 - 797. 10.52312/jdrs.2021.12
Chicago ayvaz mehmet,Göker Barlas,Leblebicioglu Gursel Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. (2021): 792 - 797. 10.52312/jdrs.2021.12
MLA ayvaz mehmet,Göker Barlas,Leblebicioglu Gursel Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. , 2021, ss.792 - 797. 10.52312/jdrs.2021.12
AMA ayvaz m,Göker B,Leblebicioglu G Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. . 2021; 792 - 797. 10.52312/jdrs.2021.12
Vancouver ayvaz m,Göker B,Leblebicioglu G Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. . 2021; 792 - 797. 10.52312/jdrs.2021.12
IEEE ayvaz m,Göker B,Leblebicioglu G "Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone." , ss.792 - 797, 2021. 10.52312/jdrs.2021.12
ISNAD ayvaz, mehmet vd. "Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone". (2021), 792-797. https://doi.org/10.52312/jdrs.2021.12
APA ayvaz m, Göker B, Leblebicioglu G (2021). Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. Joint diseases and related surgery, 32(3), 792 - 797. 10.52312/jdrs.2021.12
Chicago ayvaz mehmet,Göker Barlas,Leblebicioglu Gursel Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. Joint diseases and related surgery 32, no.3 (2021): 792 - 797. 10.52312/jdrs.2021.12
MLA ayvaz mehmet,Göker Barlas,Leblebicioglu Gursel Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. Joint diseases and related surgery, vol.32, no.3, 2021, ss.792 - 797. 10.52312/jdrs.2021.12
AMA ayvaz m,Göker B,Leblebicioglu G Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. Joint diseases and related surgery. 2021; 32(3): 792 - 797. 10.52312/jdrs.2021.12
Vancouver ayvaz m,Göker B,Leblebicioglu G Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone. Joint diseases and related surgery. 2021; 32(3): 792 - 797. 10.52312/jdrs.2021.12
IEEE ayvaz m,Göker B,Leblebicioglu G "Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone." Joint diseases and related surgery, 32, ss.792 - 797, 2021. 10.52312/jdrs.2021.12
ISNAD ayvaz, mehmet vd. "Hip-preserving reconstruction of the proximal femur witha vascularized fibula autograft and liquid-nitrogen-treatedtumor bearing bone". Joint diseases and related surgery 32/3 (2021), 792-797. https://doi.org/10.52312/jdrs.2021.12