Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer
Yıl: 2021 Cilt: 9 Sayı: 3 Sayfa Aralığı: 81 - 86 Metin Dili: İngilizce DOI: 10.5606/kbbu.2021.43660 İndeks Tarihi: 03-01-2022
Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer
Öz: Objectives: This study aimed to investigate the effect of routine bilateralneck dissection on the survival outcomes of supraglottic laryngeal cancerpatients with lateralized tumors and clinically negative necks. Patients and Methods: The data of 234 patients surgically treatedfor supraglottic squamous cell carcinoma between January 2000and September 2014 were retrospectively collected. Patients treatedpreviously for head and neck cancer, patients who could not becontacted, and those with missing data were excluded. Of theremaining 187 patients, 124 patients with early-stage primaries (T1-T2)(116 males, 8 females; mean age: 55.5±9.5 years; range, 33 to 82 years)were included. Age and sex of the patients, site of the primary tumor,TNM stage, type of the neck dissection, length of follow-up, andsurvival rates were evaluated. The tumors were classified into threegroups according to their relationship with the median line of thelarynx, and the neck dissections were recorded as unilateral or bilateral.Recurrences and survival outcomes were evaluated. Results: There was no statistically significant difference in therecurrences according to tumor site groups (p=0.39). Similarly, therewas no statistically significant difference in 10-year overall survivalrates in patient groups according to the tumor site (p=0.072). Wefound no statistically significant difference in 10-year overall survivalrates between the patients who underwent unilateral and bilateral neckdissection (p=0.580). Conclusion: Long-term survival analysis of 124 patients withsupraglottic carcinoma did not show a survival benefit of electivecontralateral neck dissection in lateralized supraglottic cancer withcontralateral clinically negative neck.
Anahtar Kelime: Supraglottik larenks kanser tedavisinde iki taraflı ve tek taraflı boyun diseksiyonu uzun dönem sonuçlarının karşılaştırılması
Öz: Amaç: Bu çalışmada lateralize tümörlü supraglottik larenks kanserihastalarında, klinik olarak negatif boyun varlığında rutin iki taraflıboyun diseksiyonunun sağkalım sonuçlarına etkisi araştırıldı. Hastalar ve Yöntemler: Skuamöz hücreli supraglottik larenkskarsinomu nedeniyle Ocak 2000 - Eylül 2014 tarihleri arasındacerrahi olarak tedavi edilen 234 hastanın verileri retrospektif olaraktoplandı. Daha önce baş ve boyun kanseri nedeniyle tedavi görenhastalar ile ulaşılamayan veya verileri eksik olan hastalar çalışma dışıbırakıldı. Geriye kalan 187 hastadan, erken evreli primerleri (T1-T2)olan 124 hasta (116 erkek, 8 kadın; ort. yaş: 55.5±9.5 yıl; dağılım,33-82 yıl) çalışmaya dahil edildi. Hastaların yaş ve cinsiyeti, primertümörün yerleşim yeri, TNM evresi, boyun diseksiyonu tipi, takipsüresi ve sağkalım oranları değerlendirildi. Tümörler larenks ortahat ile ilişkilerine göre üç gruba ayrıldı, boyun diseksiyonları da tektaraflı veya iki taraflı olarak kaydedildi. Rekürrensler ve sağkalımsonuçları değerlendirildi. Bulgular: Tümör yerleşim yerine göre oluşturulan gruplarda,rekürrens oranları arasında istatistiksel olarak anlamlı bir farkbulunmadı (p=0.39). Benzer şekilde, tümör yerleşim yerine göre10 yıllık sağkalım oranlarında da istatistiksel olarak anlamlı birfark yoktu (p=0.072). Tek taraflı ve iki taraflı boyun diseksiyonuyapılan hastalar arasında da 10 yıllık genel sağkalım oranlarıaçısından istatistiksel olarak anlamlı bir fark saptanmadı (p=0.580). Sonuç: Supraglottik karsinomlu 124 hastanın uzun dönem sağkalımanalizine göre, klinik olarak karşı taraf boynu negatif lateralizesupraglottik kanserde, elektif karşı taraf boyun diseksiyonununsağkalım üzerine avantajı gözlenmedi.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Diğer Erişim Türü: Erişime Açık
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| APA | ÜNSALER S, Zer Toros S, Sahin-Yilmaz A, OYSU C (2021). Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. , 81 - 86. 10.5606/kbbu.2021.43660 |
| Chicago | ÜNSALER SELİN,Zer Toros Sema,Sahin-Yilmaz Asli,OYSU CAGATAY Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. (2021): 81 - 86. 10.5606/kbbu.2021.43660 |
| MLA | ÜNSALER SELİN,Zer Toros Sema,Sahin-Yilmaz Asli,OYSU CAGATAY Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. , 2021, ss.81 - 86. 10.5606/kbbu.2021.43660 |
| AMA | ÜNSALER S,Zer Toros S,Sahin-Yilmaz A,OYSU C Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. . 2021; 81 - 86. 10.5606/kbbu.2021.43660 |
| Vancouver | ÜNSALER S,Zer Toros S,Sahin-Yilmaz A,OYSU C Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. . 2021; 81 - 86. 10.5606/kbbu.2021.43660 |
| IEEE | ÜNSALER S,Zer Toros S,Sahin-Yilmaz A,OYSU C "Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer." , ss.81 - 86, 2021. 10.5606/kbbu.2021.43660 |
| ISNAD | ÜNSALER, SELİN vd. "Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer". (2021), 81-86. https://doi.org/10.5606/kbbu.2021.43660 |
| APA | ÜNSALER S, Zer Toros S, Sahin-Yilmaz A, OYSU C (2021). Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. Kulak Burun Boğaz Uygulamaları, 9(3), 81 - 86. 10.5606/kbbu.2021.43660 |
| Chicago | ÜNSALER SELİN,Zer Toros Sema,Sahin-Yilmaz Asli,OYSU CAGATAY Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. Kulak Burun Boğaz Uygulamaları 9, no.3 (2021): 81 - 86. 10.5606/kbbu.2021.43660 |
| MLA | ÜNSALER SELİN,Zer Toros Sema,Sahin-Yilmaz Asli,OYSU CAGATAY Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. Kulak Burun Boğaz Uygulamaları, vol.9, no.3, 2021, ss.81 - 86. 10.5606/kbbu.2021.43660 |
| AMA | ÜNSALER S,Zer Toros S,Sahin-Yilmaz A,OYSU C Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. Kulak Burun Boğaz Uygulamaları. 2021; 9(3): 81 - 86. 10.5606/kbbu.2021.43660 |
| Vancouver | ÜNSALER S,Zer Toros S,Sahin-Yilmaz A,OYSU C Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer. Kulak Burun Boğaz Uygulamaları. 2021; 9(3): 81 - 86. 10.5606/kbbu.2021.43660 |
| IEEE | ÜNSALER S,Zer Toros S,Sahin-Yilmaz A,OYSU C "Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer." Kulak Burun Boğaz Uygulamaları, 9, ss.81 - 86, 2021. 10.5606/kbbu.2021.43660 |
| ISNAD | ÜNSALER, SELİN vd. "Long-term analysis of bilateral versus unilateral neck dissectionin the treatment of early-stage supraglottic laryngeal cancer". Kulak Burun Boğaz Uygulamaları 9/3 (2021), 81-86. https://doi.org/10.5606/kbbu.2021.43660 |
