TY  - JOUR
TI  - Frequency of peripheral blood eosinophilia and obstructive airway disease in sarcoidosis
AB  - Background/aim: There is limited information about peripheral blood eosinophilia (PBE) and airway obstruction in sarcoidosis. Since pulmonary sarcoidosis affects the airways, it is often confused with asthma. The aims of the study are to investigate airway obstruction and PBE in sarcoidosis patients and to examine the similarity of clinical presentation with asthma. Materials and methods: The patients matching the ATS/ERS/WASOG diagnosis criteria and were between 18 and 80 years of age were included consecutively between 2018 and 2020. Other diseases causing granulomas were excluded. Results: A total of 84 patients were included of which 26 (31%) had a PBE level of ≥300 µL with no significant difference seen between sarcoidosis stage and PBE (p > 0.05). A significant (p < 0.05) decrease was only seen in FEV1 as the stage of sarcoidosis progressed. Respectively 31 (36.9%), 12 (14.3%) and 4 (4.8%) patients had an obstructive, restrictive and mixed respiratory function disorder. Twenty-four (28.6%) subjects with sarcoidosis had history of asthma. Spring fever, eczema, and skin/nose allergy were noticed in 17 (20.2%) of the patients. Conclusion: Mild PBE may be seen in sarcoidosis. Patients applying with PBE, airway obstruction, bronchial hyperreactivity along with spring fever, eczema, skin/nose allergy, wheezing, chest tightness, shortness of breath and cough may be also evaluated in terms of sarcoidosis.Key words: Airway obstruction, asthma, eosinophilia, sarcoidosis
AU  - tutar, nuri
AU  - gülmez, inci
AU  - RABAHOĞLU, BİLAL
AU  - OYMAK, fatma
AU  - baran ketencioğlu, burcu
AU  - Yilmaz, Insu
DO  - 10.3906/sag-2007-87
PY  - 2021
JO  - Turkish Journal of Medical Sciences
VL  - 51
IS  - 6
SN  - 1300-0144
SP  - 3001
EP  - 3007
DB  - TRDizin
UR  - http://search/yayin/detay/477699
ER  -