Can omentin-1 be a prognostic marker in surgical intensive care patients?
Yıl: 2021 Cilt: 51 Sayı: 5 Sayfa Aralığı: 2485 - 2493 Metin Dili: İngilizce DOI: 10.3906/sag-2009-158 İndeks Tarihi: 07-01-2022
Can omentin-1 be a prognostic marker in surgical intensive care patients?
Öz: Background/aim: A member of the adipokine family, omentin-1 is selectively secreted from visceral fat tissue and the omentum. It has been shown that omentin-1 is involved in the pathogenesis of certain diseases and can be used as a prognostic marker. This study first investigated the prognostic significance of omentin-1 in surgical intensive care patients. In addition, the relationship between omentin-1 and laboratory and clinical parameters commonly used in intensive care units (ICUs) was evaluated. Materials and methods: One hundred and fifty-four patients hospitalized in the surgical ICU were included in the study. Blood samples for omentin-1 were collected from the patients displaying clinical condition changes. Changes in omentin-1 levels were observed during the hospital stay of the patients. A total of 423 blood samples were evaluated. Omentin-1 levels were compared to the laboratory parameters routinely monitored in the ICU and the prognostic significance of omentin-1 for surgical intensive care patients was investigated. Results: The median APACHE II score of all patients was (median-IQR, 8.0–6.0 ng/mL). Omentin-1 levels of the alive patients in the ICU (median-IQR, 339.04–407.68 ng/mL) were significantly higher compared to dead patients (median-IQR, 166.40–363.60 ng/ mL). Omentin-1 levels were higher in nonsepsis patients compared to the levels of the patients in sepsis and septic shock (p < 0.001). Omentin-1 values were negatively correlated with the C-reactive protein and procalcitonin levels, body temperature, and the SOFA (sequential organ failure assessment score) scores and they were positively correlated with albumin, prealbumin, and glucose levels. Conclusion: Omentin-1 may play a role in the complex constructs of inflammation and metabolic events in intensive care patients. Reduced omentin-1 levels in surgical intensive care patients were associated with poor prognosis and increased mortality.Key words: Intensive care, omentin, prognostic marker
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| APA | gultekin y, Biri İ, Gojayev A, Yilmaz Isikhan S, Portakal O, Kilic Y (2021). Can omentin-1 be a prognostic marker in surgical intensive care patients?. , 2485 - 2493. 10.3906/sag-2009-158 |
| Chicago | gultekin yucel,Biri İsmail,Gojayev Afig,Yilmaz Isikhan Selen,Portakal Oytun,Kilic Yusuf Alper Can omentin-1 be a prognostic marker in surgical intensive care patients?. (2021): 2485 - 2493. 10.3906/sag-2009-158 |
| MLA | gultekin yucel,Biri İsmail,Gojayev Afig,Yilmaz Isikhan Selen,Portakal Oytun,Kilic Yusuf Alper Can omentin-1 be a prognostic marker in surgical intensive care patients?. , 2021, ss.2485 - 2493. 10.3906/sag-2009-158 |
| AMA | gultekin y,Biri İ,Gojayev A,Yilmaz Isikhan S,Portakal O,Kilic Y Can omentin-1 be a prognostic marker in surgical intensive care patients?. . 2021; 2485 - 2493. 10.3906/sag-2009-158 |
| Vancouver | gultekin y,Biri İ,Gojayev A,Yilmaz Isikhan S,Portakal O,Kilic Y Can omentin-1 be a prognostic marker in surgical intensive care patients?. . 2021; 2485 - 2493. 10.3906/sag-2009-158 |
| IEEE | gultekin y,Biri İ,Gojayev A,Yilmaz Isikhan S,Portakal O,Kilic Y "Can omentin-1 be a prognostic marker in surgical intensive care patients?." , ss.2485 - 2493, 2021. 10.3906/sag-2009-158 |
| ISNAD | gultekin, yucel vd. "Can omentin-1 be a prognostic marker in surgical intensive care patients?". (2021), 2485-2493. https://doi.org/10.3906/sag-2009-158 |
| APA | gultekin y, Biri İ, Gojayev A, Yilmaz Isikhan S, Portakal O, Kilic Y (2021). Can omentin-1 be a prognostic marker in surgical intensive care patients?. Turkish Journal of Medical Sciences, 51(5), 2485 - 2493. 10.3906/sag-2009-158 |
| Chicago | gultekin yucel,Biri İsmail,Gojayev Afig,Yilmaz Isikhan Selen,Portakal Oytun,Kilic Yusuf Alper Can omentin-1 be a prognostic marker in surgical intensive care patients?. Turkish Journal of Medical Sciences 51, no.5 (2021): 2485 - 2493. 10.3906/sag-2009-158 |
| MLA | gultekin yucel,Biri İsmail,Gojayev Afig,Yilmaz Isikhan Selen,Portakal Oytun,Kilic Yusuf Alper Can omentin-1 be a prognostic marker in surgical intensive care patients?. Turkish Journal of Medical Sciences, vol.51, no.5, 2021, ss.2485 - 2493. 10.3906/sag-2009-158 |
| AMA | gultekin y,Biri İ,Gojayev A,Yilmaz Isikhan S,Portakal O,Kilic Y Can omentin-1 be a prognostic marker in surgical intensive care patients?. Turkish Journal of Medical Sciences. 2021; 51(5): 2485 - 2493. 10.3906/sag-2009-158 |
| Vancouver | gultekin y,Biri İ,Gojayev A,Yilmaz Isikhan S,Portakal O,Kilic Y Can omentin-1 be a prognostic marker in surgical intensive care patients?. Turkish Journal of Medical Sciences. 2021; 51(5): 2485 - 2493. 10.3906/sag-2009-158 |
| IEEE | gultekin y,Biri İ,Gojayev A,Yilmaz Isikhan S,Portakal O,Kilic Y "Can omentin-1 be a prognostic marker in surgical intensive care patients?." Turkish Journal of Medical Sciences, 51, ss.2485 - 2493, 2021. 10.3906/sag-2009-158 |
| ISNAD | gultekin, yucel vd. "Can omentin-1 be a prognostic marker in surgical intensive care patients?". Turkish Journal of Medical Sciences 51/5 (2021), 2485-2493. https://doi.org/10.3906/sag-2009-158 |
