The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards

Kaynar, Leylagul; Temel, Şahin; Yüksel, Recep Civan; Sungur, Murat; Gündoğan, Kürşat; Eser, Bülent; Alptekinoğlu Mendil, Nilgün

doi:10.3906/sag-2007-228

The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards

Nilgün APLTEKİNOĞLU MENDİL, (Erciyes Üniversitesi, Tıp Fakültesi, Yoğun Bakım Anabilim Dalı, Kayseri, Türkiye)

Şahin TEMEL, (Erciyes Üniversitesi, Tıp Fakültesi, Yoğun Bakım Anabilim Dalı, Kayseri, Türkiye)

Recep YÜKSEL, (Erciyes Üniversitesi, Tıp Fakültesi, Yoğun Bakım Anabilim Dalı, Kayseri, Türkiye)

Kürşat GÜNDOĞAN, (Erciyes Üniversitesi, Tıp Fakültesi, Yoğun Bakım Anabilim Dalı, Kayseri, Türkiye)

Bülent ESER, (Erciyes Üniversitesi, Tıp Fakültesi, Hematoloji Anabilim Dalı, İç Hastalıkları Anabilim Dalı, Kayseri, Türkiye)

Leylagül KAYNAR, (Erciyes Üniversitesi, Tıp Fakültesi, Hematoloji Anabilim Dalı, İç Hastalıkları Anabilim Dalı, Kayseri, Türkiye)

Murat SUNGUR (Erciyes Üniversitesi, Tıp Fakültesi, Yoğun Bakım Anabilim Dalı, Kayseri, Türkiye)

Turkish Journal of Medical Sciences

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Yıl: 2021 Cilt: 51 Sayı: 4 Sayfa Aralığı: 1756 - 1763 Metin Dili: İngilizce DOI: 10.3906/sag-2007-228 İndeks Tarihi: 12-01-2022

The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards

Öz:

Background/aim: High flow nasal cannula (HFNC) was mostly used in intensive care units (ICUs) with few studies in other departments. We hypothesized that HFNC applied at wards is beneficial for acute respiratory failure in hematological malignancy patients. Materials and methods: The study is a single center, randomized controlled study. Inclusion criteria were hypoxemic respiratory failure and hematological malignancy. Patients were randomized to either venturi mask/nasal cannula oxygen treatment or HFNC. Results: One hundred patients were included in the study. Median age was 58.5 (18–86) years and APACHE II score was 17 (5–29). HFNC group was 51 patients and the oxygen treatment group 49 patients. P/F ratios were similar between the groups throughout the study period. Endotracheal intubation was required in 10 (20.0%) patients in oxygen group and 17 (33.0%) patients in HFNC group (p = 0.14). A total of 17 (35.0%) patients in oxygen group and 17 (33.0%) patients in HFNC group received noninvasive mechanical ventilation (p = 0.97). Median VAS comfort scores at the 2nd and 24th hours were not different between groups. The 28-day mortality rate was 36.7% (18 deaths) in the standard group and 45.0% (23 deaths) in the HFNC group (p = 0.39). Conclusion: HFNC applied in wards is not superior to standard oxygen treatment for acute respiratory failure in hematological malignancy patients.Key words: Acute respiratory failure, high flow nasal oxygen, hematological malignancy

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Alptekinoğlu Mendil N, Temel Ş, Yüksel R, Gündoğan K, Eser B, Kaynar L, Sungur M (2021). The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. , 1756 - 1763. 10.3906/sag-2007-228
Chicago	Alptekinoğlu Mendil Nilgün,Temel Şahin,Yüksel Recep Civan,Gündoğan Kürşat,Eser Bülent,Kaynar Leylagul,Sungur Murat The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. (2021): 1756 - 1763. 10.3906/sag-2007-228
MLA	Alptekinoğlu Mendil Nilgün,Temel Şahin,Yüksel Recep Civan,Gündoğan Kürşat,Eser Bülent,Kaynar Leylagul,Sungur Murat The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. , 2021, ss.1756 - 1763. 10.3906/sag-2007-228
AMA	Alptekinoğlu Mendil N,Temel Ş,Yüksel R,Gündoğan K,Eser B,Kaynar L,Sungur M The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. . 2021; 1756 - 1763. 10.3906/sag-2007-228
Vancouver	Alptekinoğlu Mendil N,Temel Ş,Yüksel R,Gündoğan K,Eser B,Kaynar L,Sungur M The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. . 2021; 1756 - 1763. 10.3906/sag-2007-228
IEEE	Alptekinoğlu Mendil N,Temel Ş,Yüksel R,Gündoğan K,Eser B,Kaynar L,Sungur M "The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards." , ss.1756 - 1763, 2021. 10.3906/sag-2007-228
ISNAD	Alptekinoğlu Mendil, Nilgün vd. "The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards". (2021), 1756-1763. https://doi.org/10.3906/sag-2007-228

APA	Alptekinoğlu Mendil N, Temel Ş, Yüksel R, Gündoğan K, Eser B, Kaynar L, Sungur M (2021). The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. Turkish Journal of Medical Sciences, 51(4), 1756 - 1763. 10.3906/sag-2007-228
Chicago	Alptekinoğlu Mendil Nilgün,Temel Şahin,Yüksel Recep Civan,Gündoğan Kürşat,Eser Bülent,Kaynar Leylagul,Sungur Murat The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. Turkish Journal of Medical Sciences 51, no.4 (2021): 1756 - 1763. 10.3906/sag-2007-228
MLA	Alptekinoğlu Mendil Nilgün,Temel Şahin,Yüksel Recep Civan,Gündoğan Kürşat,Eser Bülent,Kaynar Leylagul,Sungur Murat The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. Turkish Journal of Medical Sciences, vol.51, no.4, 2021, ss.1756 - 1763. 10.3906/sag-2007-228
AMA	Alptekinoğlu Mendil N,Temel Ş,Yüksel R,Gündoğan K,Eser B,Kaynar L,Sungur M The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. Turkish Journal of Medical Sciences. 2021; 51(4): 1756 - 1763. 10.3906/sag-2007-228
Vancouver	Alptekinoğlu Mendil N,Temel Ş,Yüksel R,Gündoğan K,Eser B,Kaynar L,Sungur M The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards. Turkish Journal of Medical Sciences. 2021; 51(4): 1756 - 1763. 10.3906/sag-2007-228
IEEE	Alptekinoğlu Mendil N,Temel Ş,Yüksel R,Gündoğan K,Eser B,Kaynar L,Sungur M "The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards." Turkish Journal of Medical Sciences, 51, ss.1756 - 1763, 2021. 10.3906/sag-2007-228
ISNAD	Alptekinoğlu Mendil, Nilgün vd. "The use of high-flow nasal oxygen vs. standard oxygen therapy in hematological malignancy patients with acute respiratory failure in hematology wards". Turkish Journal of Medical Sciences 51/4 (2021), 1756-1763. https://doi.org/10.3906/sag-2007-228