Yıl: 2021 Cilt: 51 Sayı: 3 Sayfa Aralığı: 1229 - 1233 Metin Dili: İngilizce DOI: 10.3906/sag-2008-18 İndeks Tarihi: 18-01-2022

Lack of awareness of Hepatitis B screening and vaccination in high-risk group

Öz:
Background/aim: Hepatitis B virus (HBV) vaccination rates are insufficient in high-risk patients worldwide. This study aimed to investigate the screening, immunization, and vaccination rates in three high-risk groups for HBV infection: allogeneic hematopoietic stem cell transplantation (AHSCT), renal transplantation (RT), and chronic hepatitis C (CHC) groups. Materials and methods: The serological data of consecutive patients between 2014 and 2019 were reviewed using the hospital database. Results: The HBV screening rates were 100.0%, 90.4%, and 82.4% in the AHSCT, CHC, and RT groups, respectively (p = 0.003). The immunization rates against HBV through either previous exposure or vaccination were 79.5%, 71.7%, and 46.5% in the AHSCT, RT, and CHC groups, respectively (p < 0.001). The HBV vaccination rate was significantly low in the CHC group (71.5%, 69.0%, 34.6% in the AHSCT, RT, and CHC groups, respectively, p < 0.001). If patients lost their immunity due to immunosuppressive therapy were accounted, the vaccination rates increased to 95.2% in the AHSCT group and 72.9% in the RT group. The rate of annual screening for HBV status was 97.9% in the AHSCT group, but it was only 23.9% in the RT group. Conclusion: HBV screening and vaccination rates were significantly lower in the RT and CHC groups than in the AHSCT group.Key words: Vaccination, Hepatitis B virus, immunity
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Salama, II, Sami SM, Said ZN, Salama SI, Rabah TM et al. Early and long term anamnestic response to HBV booster dose among fully vaccinated Egyptian children during infancy. Vaccine 2018; 36: 2005-2011. doi: 10.1016/j.vaccine.2018.02.103
  • 2. Akyıldız M, Ahıskalı E, Zeybel M, Yurdaydın C. Regional epidemiology, burden and management of hepatits B virus in the Middle East. Clinical Liver Disease 2019; 14: 212-214. doi: 10.1002/cld.887
  • 3. Gurol E, Saban C, Oral O, Cigdem A, Armagan A. Trends in hepatitis B and hepatitis C virus among blood donors over 16 years in Turkey. European Journal of Epidemiology 2006; 21: 299-305. doi: 10.1007/s10654-006-0001-2
  • 4. Üner A, Kırımi E, Tuncer İ, Ceylan A, Türkdoğan MK et al. Seroepidemiology of hepatitis B virus infection in children in the Eastern Anatolia. Eastern Journal of Medicine 2001; 6: 40- 42.
  • 5. Tozun N, Ozdogan O, Cakaloglu Y, Idilman R, Karasu Z et al. Seroprevalence of hepatitis B and C virus infections and risk factors in Turkey: a fieldwork TURHEP study. Clinical Microbiology and Infection 2015; 21: 1020-1026. doi: 10.1016/j. cmi.2015.06.028
  • 6. Schillie S, Vellozzi C, Reingold A, Harris A, Haber P et al. Prevention of hepatitis B virus infection in the United States: recommendation of the Advisory Committee on Immunization Practices. MMWR. Recommendations and Reports 2018; 67: 1-31. doi: 10.15585/mmwr.rr6701a1
  • 7. Burton CE, Doucette KE, Mabilangan CA, Plitt SS, Lee BE et al. Hepatitis B and C serologic profiles of Canadian organ donors and recipients: retrospective 10-year review at a single center. Transplant Infectious Disease 2016; 18: 520-528. doi: 10.1111/ tid.12558
  • 8. Williams WW, Lu PJ, O’Halloran A, Kim DK, Ghroskopf LA et al. Surveillance of vaccination coverage among adult populations—United States, 2015. MMWR CDC Surveillance Summaries 2017; 66: 1–28. doi: 10.15585/mmwr.ss6611a1
  • 9. Stroffolini T, Sagnelli E, Sagnelli C, Smedile A, Furlan C et al. The burden of HBV infection in HCV patients in Italy and the risk of reactivation under DAA therapy. Digestive and Liver Disease 2019; 51: 434-437. doi: 10.1016/j.dld.2018.09.010
  • 10. Launay O, Le Strat Y, Tosini W, Kara L, Quelet S et al. Impact of free on-site vaccine and/or healthcare workers training on hepatitis B vaccination acceptability in high-risk subjects: a pre-post cluster randomized study. Clinical Microbiology and Infection 2014; 20: 1033-1039. doi: 10.1111/1469-0691.12689
  • 11. Bini EJ, Perumalswami PV. Hepatitis B virus infection among American patients with chronic hepatitis C virus infection: prevalence, racial/ethnic differences, and viral interactions. Hepatology 2010; 51: 759-766. doi: 10.1002/hep.23461
  • 12. Urbini Dos Santos C, Sevá-Pereira T, Alves-Filho G, Lorena SL, Soares EC et al. Changes in serological markers of hepatitis B virus after renal transplantation. Transplantation Proceedings 2008; 40: 749-751. doi: 10.1016/j.transproceed.2008.02.066
  • 13. Çakar MK, Suyani E, Sucak GT, Altindal Ş, Aki SZ et al. HBV-related events after allogeneic hematopoetic stem cell transplantation in a center from Turkey. Annals of Hematology 2013; 92: 395-402. doi: 10.1007/s00277-012-1620-1
APA balaban h, Aslan A, Ayar Ş, Dag O, ALP A, Simsek C, vahabov j, YILDIRIM T, GOKKER H, Buyukasik Y, simsek h (2021). Lack of awareness of Hepatitis B screening and vaccination in high-risk group. , 1229 - 1233. 10.3906/sag-2008-18
Chicago balaban hatice yasemin,Aslan Abdullah Tarık,Ayar Şefika Nur,Dag Osman,ALP ALPASLAN,Simsek Cem,vahabov javanshir,YILDIRIM Tolga,GOKKER HAKAN,Buyukasik Yahya,simsek halis Lack of awareness of Hepatitis B screening and vaccination in high-risk group. (2021): 1229 - 1233. 10.3906/sag-2008-18
MLA balaban hatice yasemin,Aslan Abdullah Tarık,Ayar Şefika Nur,Dag Osman,ALP ALPASLAN,Simsek Cem,vahabov javanshir,YILDIRIM Tolga,GOKKER HAKAN,Buyukasik Yahya,simsek halis Lack of awareness of Hepatitis B screening and vaccination in high-risk group. , 2021, ss.1229 - 1233. 10.3906/sag-2008-18
AMA balaban h,Aslan A,Ayar Ş,Dag O,ALP A,Simsek C,vahabov j,YILDIRIM T,GOKKER H,Buyukasik Y,simsek h Lack of awareness of Hepatitis B screening and vaccination in high-risk group. . 2021; 1229 - 1233. 10.3906/sag-2008-18
Vancouver balaban h,Aslan A,Ayar Ş,Dag O,ALP A,Simsek C,vahabov j,YILDIRIM T,GOKKER H,Buyukasik Y,simsek h Lack of awareness of Hepatitis B screening and vaccination in high-risk group. . 2021; 1229 - 1233. 10.3906/sag-2008-18
IEEE balaban h,Aslan A,Ayar Ş,Dag O,ALP A,Simsek C,vahabov j,YILDIRIM T,GOKKER H,Buyukasik Y,simsek h "Lack of awareness of Hepatitis B screening and vaccination in high-risk group." , ss.1229 - 1233, 2021. 10.3906/sag-2008-18
ISNAD balaban, hatice yasemin vd. "Lack of awareness of Hepatitis B screening and vaccination in high-risk group". (2021), 1229-1233. https://doi.org/10.3906/sag-2008-18
APA balaban h, Aslan A, Ayar Ş, Dag O, ALP A, Simsek C, vahabov j, YILDIRIM T, GOKKER H, Buyukasik Y, simsek h (2021). Lack of awareness of Hepatitis B screening and vaccination in high-risk group. Turkish Journal of Medical Sciences, 51(3), 1229 - 1233. 10.3906/sag-2008-18
Chicago balaban hatice yasemin,Aslan Abdullah Tarık,Ayar Şefika Nur,Dag Osman,ALP ALPASLAN,Simsek Cem,vahabov javanshir,YILDIRIM Tolga,GOKKER HAKAN,Buyukasik Yahya,simsek halis Lack of awareness of Hepatitis B screening and vaccination in high-risk group. Turkish Journal of Medical Sciences 51, no.3 (2021): 1229 - 1233. 10.3906/sag-2008-18
MLA balaban hatice yasemin,Aslan Abdullah Tarık,Ayar Şefika Nur,Dag Osman,ALP ALPASLAN,Simsek Cem,vahabov javanshir,YILDIRIM Tolga,GOKKER HAKAN,Buyukasik Yahya,simsek halis Lack of awareness of Hepatitis B screening and vaccination in high-risk group. Turkish Journal of Medical Sciences, vol.51, no.3, 2021, ss.1229 - 1233. 10.3906/sag-2008-18
AMA balaban h,Aslan A,Ayar Ş,Dag O,ALP A,Simsek C,vahabov j,YILDIRIM T,GOKKER H,Buyukasik Y,simsek h Lack of awareness of Hepatitis B screening and vaccination in high-risk group. Turkish Journal of Medical Sciences. 2021; 51(3): 1229 - 1233. 10.3906/sag-2008-18
Vancouver balaban h,Aslan A,Ayar Ş,Dag O,ALP A,Simsek C,vahabov j,YILDIRIM T,GOKKER H,Buyukasik Y,simsek h Lack of awareness of Hepatitis B screening and vaccination in high-risk group. Turkish Journal of Medical Sciences. 2021; 51(3): 1229 - 1233. 10.3906/sag-2008-18
IEEE balaban h,Aslan A,Ayar Ş,Dag O,ALP A,Simsek C,vahabov j,YILDIRIM T,GOKKER H,Buyukasik Y,simsek h "Lack of awareness of Hepatitis B screening and vaccination in high-risk group." Turkish Journal of Medical Sciences, 51, ss.1229 - 1233, 2021. 10.3906/sag-2008-18
ISNAD balaban, hatice yasemin vd. "Lack of awareness of Hepatitis B screening and vaccination in high-risk group". Turkish Journal of Medical Sciences 51/3 (2021), 1229-1233. https://doi.org/10.3906/sag-2008-18