Yıl: 2021 Cilt: 28 Sayı: 11 Sayfa Aralığı: 2059 - 2064 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2021.02.189 İndeks Tarihi: 18-01-2022

Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy

Öz:
Aim: This study aimed to investigate the frequency at which physicians test hepatitis B virus (HBV) serology before treatment and the rate of hepatitis B virus reactivation (HBVr) after treatment in patients undergoing chemotherapy (CT) due to a solid organ malignancy (SOM) or hematological malignancy (HM). Materials and Methods: Baseline clinical feature, HBV serology, and liver function test data for 1275 patients ≥ 18 years of age who underwent CT for the first time due to various SOMs and HMs from 2015-2017 were obtained from the database and retrospectively analyzed. HBV serology was studied in 296 (201 HM, 95 SOM) of the 1275 patients retrieved from the database. Results: The prevalence of HBV was 9.5% (121 patients). Only 49 (40.4%) HBV-positive patients had HBV DNA. Of those, 72 (59.5%) underwent prophylactic antiviral therapy. HBVr was detected in only 3 patients (1.5%), and all of those patients had HMs and were recommended oral antiviral therapy but did not. Conclusion: In patients with SOMs, the screening rates of HBV serology, as well as prophylaxis and follow-up HMs were extremely low. Therefore, these patients should be screened for HBV serology and prophylactic treatment should be given when necessary for HBVr.
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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Cengiz M, Seckin Y, Cagin Y, Nuransoy Cengiz A (2021). Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. , 2059 - 2064. 10.5455/annalsmedres.2021.02.189
Chicago Cengiz Muhammet,Seckin Yuksel,Cagin Yasir Furkan,Nuransoy Cengiz Ayşe Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. (2021): 2059 - 2064. 10.5455/annalsmedres.2021.02.189
MLA Cengiz Muhammet,Seckin Yuksel,Cagin Yasir Furkan,Nuransoy Cengiz Ayşe Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. , 2021, ss.2059 - 2064. 10.5455/annalsmedres.2021.02.189
AMA Cengiz M,Seckin Y,Cagin Y,Nuransoy Cengiz A Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. . 2021; 2059 - 2064. 10.5455/annalsmedres.2021.02.189
Vancouver Cengiz M,Seckin Y,Cagin Y,Nuransoy Cengiz A Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. . 2021; 2059 - 2064. 10.5455/annalsmedres.2021.02.189
IEEE Cengiz M,Seckin Y,Cagin Y,Nuransoy Cengiz A "Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy." , ss.2059 - 2064, 2021. 10.5455/annalsmedres.2021.02.189
ISNAD Cengiz, Muhammet vd. "Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy". (2021), 2059-2064. https://doi.org/10.5455/annalsmedres.2021.02.189
APA Cengiz M, Seckin Y, Cagin Y, Nuransoy Cengiz A (2021). Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. Annals of Medical Research, 28(11), 2059 - 2064. 10.5455/annalsmedres.2021.02.189
Chicago Cengiz Muhammet,Seckin Yuksel,Cagin Yasir Furkan,Nuransoy Cengiz Ayşe Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. Annals of Medical Research 28, no.11 (2021): 2059 - 2064. 10.5455/annalsmedres.2021.02.189
MLA Cengiz Muhammet,Seckin Yuksel,Cagin Yasir Furkan,Nuransoy Cengiz Ayşe Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. Annals of Medical Research, vol.28, no.11, 2021, ss.2059 - 2064. 10.5455/annalsmedres.2021.02.189
AMA Cengiz M,Seckin Y,Cagin Y,Nuransoy Cengiz A Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. Annals of Medical Research. 2021; 28(11): 2059 - 2064. 10.5455/annalsmedres.2021.02.189
Vancouver Cengiz M,Seckin Y,Cagin Y,Nuransoy Cengiz A Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy. Annals of Medical Research. 2021; 28(11): 2059 - 2064. 10.5455/annalsmedres.2021.02.189
IEEE Cengiz M,Seckin Y,Cagin Y,Nuransoy Cengiz A "Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy." Annals of Medical Research, 28, ss.2059 - 2064, 2021. 10.5455/annalsmedres.2021.02.189
ISNAD Cengiz, Muhammet vd. "Investigation of hepatitis B virus prevalence and reactivation frequency in malignancy patients administering chemotherapy". Annals of Medical Research 28/11 (2021), 2059-2064. https://doi.org/10.5455/annalsmedres.2021.02.189