Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels

Balbaloglu, Ozlem; Göçer, Şemsinnur

doi:10.31067/acusaglik.948574

Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels

Şemsinnur Göçer, (Bozok Üniversitesi, Sarıkaya Fizik Terapi ve Rehabilitasyon Yüksek Okul, Yozgat, Türkiye)

Özlem Balbaloğlu (Bozok Üniversitesi, Tıp Fakültesi, Yozgat, Türkiye)

Acıbadem Üniversitesi Sağlık Bilimleri Dergisi

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Yıl: 2022 Cilt: 13 Sayı: 1 Sayfa Aralığı: 119 - 125 Metin Dili: İngilizce DOI: 10.31067/acusaglik.948574 İndeks Tarihi: 28-02-2022

Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels

Öz:

Objective: Studies investigating the effect of vitamin D and parathyroid hormone (PTH) in frailty syndrome are limited. Therefore, we aimed to evaluate the relationship between frailty and serum vitamin D and PTH levels. Material and Methods: This is a cross-sectional study conducted on individuals aged >65 years. In this cross-sectional study, data were collected using sociodemographic data sheet, Fatigue, Resistance, Ambulation, Illnesses, & Loss of Weight (FRAIL) scale and Study of Osteoporotic Fracture (SOF) index via face-to-face interview. The study included data from 513 subjects. Chi-square test was used in analyses. A p value<0.05 was considered as statistically significant. Results: The mean age was 71.9±6.4 years in the study population. The prevalence of frailty elder was found as 46.8% by FRAIL scale and 51.3% by SOF index while pre-fail elder prevalence was found as 45.2% by FRAIL scale and 33.3% by SOF index. Conclusion: In our study it was found that frail elder prevalence was increased by advancing age, female gender and presence of comorbidity and that low serum vitamin D and elevated PTH levels were closely associated with prevalence of frail elder.

Anahtar Kelime:

Kırılganlığın Serum D Vitamini Ve Paratiroid Hormon Düzeyleriyle İlişkisi

Öz:

Amaç: Kırılgan yaşlı sendromunun patobiyolojisi ile ilgili bilgiler kısıtlıdır. Kırılgan yaşlı sendromunun biyolojik yaşlanmaya bağlı oluşan hematolojik, immünolojik, endokrin ve metabolik sistemdeki değişiklikler ile birlikte çevresel faktörlerin sorumlu olabileceği düşünülmektedir. Bu araştırmanın amacı 65 yaş ve üzeri bireylerde kan bazlı biyobelirteçler ve kırılganlık arasındaki ilişkinin iki farklı kırılganlık indeksine göre değerlendirilmesidir. Gereç ve Yöntemler: Bu çalışma 65 yaş ve üzeri bireylerde kan bazlı biyobelirteçler ve kırılganlık arasındaki ilişkinin belirlenmesi amacıyla yapılmış kesitsel bir çalışmadır. Veriler; sosyodemografik anket formu, FRAİL Kırılganlık Ölçeği ve Osteoporotik Kırık Çalışma İndeksi kullanılarak toplanmıştır. Veriler yüz yüze görüşme yöntemiyle toplanmış ve 513 kişiye ait veriler değerlendirilmiştir. Analizlerde Pearson’s Ki kare testi kullanılmış olup, p<0.05 değeri anlamlı kabul edilmiştir. Bulgular: Araştırma grubumuzun yaş ortalaması 71.9 ± 6.4 yıl idi. Kırılgan yaşlı prevalansı FRAİL İndekse göre %46.8 iken SOF İndeksine göre %51.3; pre-frail olanların prevalansı ise FRAİL İndeksine göre %45.2 iken SOF İndeksine göre %33.3 bulundu. Sonuç: Çalışmamızda, kırılgan yaşlı prevalansının, yaşın ilerlemesi, kadın cinsiyet ve komorbidite ile artış gösterdiği, ayrıca serumda düşük D vit düzeyi ile yüksek PTH düzeylerinin de KYS ile yakından ilişkili olduğu bulunmuştur.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Göçer Ş, Balbaloglu O (2022). Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. , 119 - 125. 10.31067/acusaglik.948574
Chicago	Göçer Şemsinnur,Balbaloglu Ozlem Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. (2022): 119 - 125. 10.31067/acusaglik.948574
MLA	Göçer Şemsinnur,Balbaloglu Ozlem Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. , 2022, ss.119 - 125. 10.31067/acusaglik.948574
AMA	Göçer Ş,Balbaloglu O Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. . 2022; 119 - 125. 10.31067/acusaglik.948574
Vancouver	Göçer Ş,Balbaloglu O Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. . 2022; 119 - 125. 10.31067/acusaglik.948574
IEEE	Göçer Ş,Balbaloglu O "Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels." , ss.119 - 125, 2022. 10.31067/acusaglik.948574
ISNAD	Göçer, Şemsinnur - Balbaloglu, Ozlem. "Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels". (2022), 119-125. https://doi.org/10.31067/acusaglik.948574

APA	Göçer Ş, Balbaloglu O (2022). Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, 13(1), 119 - 125. 10.31067/acusaglik.948574
Chicago	Göçer Şemsinnur,Balbaloglu Ozlem Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 13, no.1 (2022): 119 - 125. 10.31067/acusaglik.948574
MLA	Göçer Şemsinnur,Balbaloglu Ozlem Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, vol.13, no.1, 2022, ss.119 - 125. 10.31067/acusaglik.948574
AMA	Göçer Ş,Balbaloglu O Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi. 2022; 13(1): 119 - 125. 10.31067/acusaglik.948574
Vancouver	Göçer Ş,Balbaloglu O Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels. Acıbadem Üniversitesi Sağlık Bilimleri Dergisi. 2022; 13(1): 119 - 125. 10.31067/acusaglik.948574
IEEE	Göçer Ş,Balbaloglu O "Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels." Acıbadem Üniversitesi Sağlık Bilimleri Dergisi, 13, ss.119 - 125, 2022. 10.31067/acusaglik.948574
ISNAD	Göçer, Şemsinnur - Balbaloglu, Ozlem. "Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels". Acıbadem Üniversitesi Sağlık Bilimleri Dergisi 13/1 (2022), 119-125. https://doi.org/10.31067/acusaglik.948574