Myalgia-arthralgia and Associated Factors in Patients with COVID-19

EREN, Fettah; Demir, Ayşegül; Bakdık, Bengü

doi:10.4274/tnd.2021.85453

Myalgia-arthralgia and Associated Factors in Patients with COVID-19

Fettah Eren, (Selçuk Üniversitesi, Tıp Fakültesi, Nöroloji Anabilim Dalı, Konya, Türkiye)

Bengü Özkan, (Sağlık Bilimleri Üniversitesi, Konya Şehir Hastanesi, Göğüs Hastalıkları Kliniği, Konya, Türkiye)

Ayşegül Demir (Sağlık Bilimleri Üniversitesi, Konya Şehir Hastanesi, Nöroloji Kliniği, Konya, Türkiye)

Türk Nöroloji Dergisi

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Yıl: 2021 Cilt: 27 Sayı: Özel Sayı 1 Sayfa Aralığı: 15 - 20 Metin Dili: İngilizce DOI: 10.4274/tnd.2021.85453 İndeks Tarihi: 20-01-2022

Myalgia-arthralgia and Associated Factors in Patients with COVID-19

Öz:

Objective: This study aimed to investigate the psychogenic impact of coronavirus disease-2019 (COVID-19) and its association with myalgia-arthralgia in patients who are hospitalized with COVID-19. Materials and Methods: This study includes patients who were hospitalized with COVID-19 and whose diagnoses were confirmed by thoracic computed tomography findings and positive polymerase chain reaction test. Characteristics of pain were evaluated using the pain quality assessment scale (PQAS). Posttraumatic stress disorder (PTSD) was evaluated with the impact of event scale-revised (IES-R). Scoring over 33 was considered a cut-off point for “probable PTSD”. These patients were named PTSD (+). PTSD (+) and PTSD (-) groups were compared in terms of PQAS and laboratory parameters. Results: Of the participants, 70 (42.9%) were females and 93 (57.1%) were males. The mean IES-R score was 36.89±11.76. The prevalence of PTSD was 47.9% (n=78). The most common pain was back pain (n=52, 50.5%). Patients with myalgia-arthralgia had higher total IES-R score and subgroup scores (p=0.008, p=0.010, p=0.006, and p=0.012, respectively). The patient group with PTSD had higher PQAS score (p=0.001). Additionally, this group had lower leukocyte (p=0.002) and lymphocyte counts (p=0.010) and higher serum creatine kinase level (p=0.02). Conclusion: Approximately half of the patients who were hospitalized with COVID-19 had PTSD, with a higher incidence and severity of myalgia-arthralgia. Therefore, myalgia-arthralgia was associated with PTSD in patients who were hospitalized with COVID-19.

Anahtar Kelime:

COVID-19’lu Hastalarda Kas Eklem Ağrıları ve İlişkili Faktörler

Öz:

Amaç: Çalışmanın amacı, hastanede yatan koronavirüs hastalığı-2019’lu (COVID-19) hastalarda COVID-19’un emosyonel etkisini ve miyalji-artralji ilişkisini araştırmaktır. Gereç ve Yöntem: Bu çalışmaya, toraks bilgisayarlı tomografi ve polimeraz zincir reaksiyonu sonucuna göre tanısı konulan hastanede yatan COVID-19’lu hastalar dahil edildi. Ağrının karakteristiği, ağrı kalitesi değerlendirme ölçeği (PQAS) kullanılarak değerlendirildi. Travma sonrası stres bozukluğu (TSSB), revize olayların etkisi ölçeği (OEÖ-R) ölçeği ile değerlendirildi. Otuz üç üzeri puan, “olası bir TSSB olgusu” için kesme noktası olarak kabul edildi. Bu olgulara TSSB (+) adı verildi. TSSB (+) ve TSSB (-) grupları PQAS ve laboratuvar parametreleri açısından karşılaştırıldı. Bulgular: Katılımcıların 70’i (%42,9) kadın, 93’ü (%57,1) erkekti. OEÖ-R puanı ortalaması 36,89±11,76 idi. TSSB prevalansı %47,9 (n=78) idi. En sık görülen ağrı sırt ağrısıydı (n=52, %50,5). Miyalji-artraljisi olan hastalarda OEÖ-R ve alt grup skoru daha yüksekti (sırasıyla; p=0,008, p=0,010, p=0,006 ve p=0,012). PTSB’si olan hasta grubunun PQAS skoru daha yüksekti (p=0,001). Ayrıca bu grupta lökosit (p=0,002), lenfosit (p=0,010) ve serum kreatinin kinaz seviyesi (p=0,02) daha düşüktü. Sonuç: Hastanede yatan COVID-19’lu hastaların yaklaşık yarısında TSSB vardır. Bu hastalarda miyalji-artralji insidansı ve şiddeti daha yüksektir. Miyaljiartralji, hastanede yatan COVID-19’lu hastalarda TSSB ile ilişkilidir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	EREN F, Bakdık B, Demir A (2021). Myalgia-arthralgia and Associated Factors in Patients with COVID-19. , 15 - 20. 10.4274/tnd.2021.85453
Chicago	EREN Fettah,Bakdık Bengü,Demir Ayşegül Myalgia-arthralgia and Associated Factors in Patients with COVID-19. (2021): 15 - 20. 10.4274/tnd.2021.85453
MLA	EREN Fettah,Bakdık Bengü,Demir Ayşegül Myalgia-arthralgia and Associated Factors in Patients with COVID-19. , 2021, ss.15 - 20. 10.4274/tnd.2021.85453
AMA	EREN F,Bakdık B,Demir A Myalgia-arthralgia and Associated Factors in Patients with COVID-19. . 2021; 15 - 20. 10.4274/tnd.2021.85453
Vancouver	EREN F,Bakdık B,Demir A Myalgia-arthralgia and Associated Factors in Patients with COVID-19. . 2021; 15 - 20. 10.4274/tnd.2021.85453
IEEE	EREN F,Bakdık B,Demir A "Myalgia-arthralgia and Associated Factors in Patients with COVID-19." , ss.15 - 20, 2021. 10.4274/tnd.2021.85453
ISNAD	EREN, Fettah vd. "Myalgia-arthralgia and Associated Factors in Patients with COVID-19". (2021), 15-20. https://doi.org/10.4274/tnd.2021.85453

APA	EREN F, Bakdık B, Demir A (2021). Myalgia-arthralgia and Associated Factors in Patients with COVID-19. Türk Nöroloji Dergisi, 27(Özel Sayı 1), 15 - 20. 10.4274/tnd.2021.85453
Chicago	EREN Fettah,Bakdık Bengü,Demir Ayşegül Myalgia-arthralgia and Associated Factors in Patients with COVID-19. Türk Nöroloji Dergisi 27, no.Özel Sayı 1 (2021): 15 - 20. 10.4274/tnd.2021.85453
MLA	EREN Fettah,Bakdık Bengü,Demir Ayşegül Myalgia-arthralgia and Associated Factors in Patients with COVID-19. Türk Nöroloji Dergisi, vol.27, no.Özel Sayı 1, 2021, ss.15 - 20. 10.4274/tnd.2021.85453
AMA	EREN F,Bakdık B,Demir A Myalgia-arthralgia and Associated Factors in Patients with COVID-19. Türk Nöroloji Dergisi. 2021; 27(Özel Sayı 1): 15 - 20. 10.4274/tnd.2021.85453
Vancouver	EREN F,Bakdık B,Demir A Myalgia-arthralgia and Associated Factors in Patients with COVID-19. Türk Nöroloji Dergisi. 2021; 27(Özel Sayı 1): 15 - 20. 10.4274/tnd.2021.85453
IEEE	EREN F,Bakdık B,Demir A "Myalgia-arthralgia and Associated Factors in Patients with COVID-19." Türk Nöroloji Dergisi, 27, ss.15 - 20, 2021. 10.4274/tnd.2021.85453
ISNAD	EREN, Fettah vd. "Myalgia-arthralgia and Associated Factors in Patients with COVID-19". Türk Nöroloji Dergisi 27/Özel Sayı 1 (2021), 15-20. https://doi.org/10.4274/tnd.2021.85453