Yıl: 2021 Cilt: 51 Sayı: 2 Sayfa Aralığı: 393 - 399 Metin Dili: İngilizce DOI: 10.3906/sag-2005-315 İndeks Tarihi: 20-01-2022

Vertebral compression fractures: Still an unpredictable aspect of osteoporosis

Öz:
Abstract: Vertebral compression fracture is a hallmark of osteoporosis (OP) and by far the most prevalent fragility fracture. It is well proven that patients who develop a vertebral compression fracture are at substantial risk for additional fractures. Diagnosis is based on adequate clinical evaluation, imaging, and laboratory tests. The imaging of OP and fragility fractures includes conventional radiology to evaluate spinal fractures, bone mineral density (BMD) testing by dual energy x-ray densitometry, quantitative computerized tomography, magnetic resonance imaging, bone scintigraphy (if necessary), and ultrasound. Screening and treatment of individuals with high risk of osteoporotic fracture are cost-effective, but approximately two-thirds of the vertebral compression fractures (VCF) that occur each year are not accurately diagnosed and, therefore, not treated. Evaluation of VCFs, even though they may be asymptomatic, seems essential to health-related and/or clinical research on OP.Key words: Osteoporosis, spine, spinal fractures, bone density
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Pisani P, Renna MD, Conversano F, Casciaro E, Di Paola M. et al. Major osteoporotic fragility fractures: Risk factor updates and societal impact. World Journal of Orthopaedics 2016 Mar 18; 7 (3): 171-181. doi: 10.5312/wjo.v7.i3.171
  • 2. Griffith J F. Identifying osteoporotic vertebral fracture. Quantitative Imaging in Medicine and Surgery 2015; 5 (4). doi: 10.3978/j.issn.2223-4292.2015.08.01
  • 3. Kamimura, M, Nakamura Y , Sugino N, Uchiyama S, , Komatsu M. et al. Associations of self-reported height loss and kyphosis with vertebral fractures in Japanese women 60 years and older: a cross-sectional survey. Scientific Reports 2016; 6: 29199. doi: 10.1038/srep29199
  • 4. Lewiecki EM, Jaster AJ. Clinical review: Clinical applications of vertebral fracture assessment by dual-energy x-ray absorptiometry. The Journal of Clinical Endocrinology and Metabolism 2006; 91 (11): 4215-4222. doi: 10.1210/jc.2006- 1178
  • 5. Malgo F, Hamdy NAT, Ticheler CHJM. Smit F, Kroon HM et al. Value and potential limitations of vertebral fracture assessment (VFA) compared to conventional spine radiography: experience from a fracture liaison service (FLS) and a metaanalysis. Osteoporosis International 2017; 28, 2955-2965. doi: 10.1007/s00198-017-4137-6.
  • 6.. Dionyssiotis Y. Management of osteoporotic vertebral fractures. International Journal of General Medicine 2010; 3: 167-171. doi: 10.2147/ijgm.s11751
  • 7. Jager PL, Jonkman, S, Koolhaas, W, Stiekema A, Wolffenbuttel BHR et al. Combined vertebral fracture assessment and bone mineral density measurement: a new standard in the diagnosis of osteoporosis in academic populations. Osteoporosis International 2011; 22, 1059-1068. doi: 10.1007/s00198-010- 1293-3
  • 8. Ong T, Kantachuvesiri P, Sahota O, Gladman JRF. Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review. Age and Ageing 2018; 47 (1): 17-25. doi: 10.1093/ageing/afx079.
  • 9. Li Y, Yan L, Cai S, Wang P, Zhuang H, Yu H. The prevalence and under-diagnosis of vertebral fractures on chest radiograph. BMC Musculoskeletal Disorders 2018; 19: 235. doi: 10.1186/ s12891-018-2171-y
  • 10. Odabası E, Turan M, Tekbaş F, Kutlu M. Evaluation of osteoporotic fractures in a group of Turkish women.Turkish Journal of Medical Sciences 2009; 39 (1): 21-28. doi:10.3906/ sag-0801-6
  • 11. Küçükler FK, Simsek Y, Turk AÇ, Arduc A, Guler S. Osteoporosis and silent vertebral fractures in nursing home resident elderly men in Turkey. Journal of Clinical Densitometry 2017; 20 (2): 188-195. doi: 10.1016/j.jocd.2015.05.064
  • 12. Nuti R, Brandi ML, Checchia G, Di Munno O, Dominguez L et al. Guidelines for the management of osteoporosis and fragility fractures. Internal and Emergency Medicine 2019;14, 85-102. doi: 10.1007/s11739-018-1874-2
  • 13. Gokce Kutsal Y, Ozdemir O, Karahan S, Akyol Y, Borman P et al. Musculoskeletal pain in osteoporotic elderly patients: a multicenter study. Turkish Journal of Physical Medicine and Rehabilitation 2012; 58: 263-266. doi: 10.4274/ tftr .04706
  • 14. Hopman WM, Berger C, Joseph L, Morin SN, Towheed T et al. Longitudinal assessment of health-related quality of life in osteoporosis: data from the population-based Canadian Multicentre Osteoporosis Study. Osteoporosis International 2019; 30 (8): 1635-1644. doi: 10.1007/s00198-019-05000-y.
  • 15. Gokce Kutsal Y. Still a major concern: osteoporosis has a serious ımpact on quality of life. Turkish Journal of Osteoporosis 2020; 26:1-5. doi: 10.4274/tod.galenos.2020.17136
  • 16. Papaioannou A, Kennedy CC, Ioannidis G, Sawka A, Hopman WM et al. The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian multicentre osteoporosis study. Osteoporosis International 2009; 20 (5): 703-714. doi: 10.1007/s00198-008-0743-7
  • 17. Guillemin F, Martinez L, Calvert M, Cooper C, Ganiats T et al. Fear of falling, fracture history, and comorbidities are associated with health-related quality of life among European and US women with osteoporosis in a large international study. Osteoporosis International 2013; 24 (12): 3001-3010. doi: 10.1007/s00198-013-2408-4
  • 18. Lips P, van Schoor NM. Quality of life in patients with osteoporosis. Osteoporosis International 2005; 16 (5): 447-455. doi: 10.1007/s00198-004-1762-7
  • 19. Peasgood T, Hermann K, Kanis JA, Brazier JE. An updated systematic review of Health State Utility Values for osteoporosis related conditions. Osteoporosis International 2009; 20 (6): 853-868. doi: 10.1007/s00198-009-0844-y
  • 20. Thompson DR, Yu CM. Quality of life in patients with coronary heart disease-I: assessment tools. Health and Quality of Life Outcomes 2003; 1: 42. doi: 10.1186/1477-7525-1-42
  • 21. Waterloo S, Søgaard AJ, Ahmed LA, Damsgård E, Morseth B et al. Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007–08. BMC Geriatrics 2013 13:102. doi: 10.1186/1471-2318-13-102.
  • 22. Salaffi F, Cimmino MA, Malavolta N, Carotti M, Di Matteo L et al. The burden of prevalent fractures on health-related quality of life in postmenopausal women with osteoporosis: the IMOF study. The Journal of Rheumatology 2007; 34:1551-1560. PMID: 17516618
  • 23. El Maghraoui A , Mounach A, Rezqi A, Achemlal L, Bezza A et al. Vertebral fracture assessment in asymptomatic men and its impact on management, Bone 2012; 50 (4): 853-857. doi: 10.1016/j.bone.2011.12.018
  • 24. Kanis JA, Hans D, Cooper C, Baim S, Bilezikian JP et al. Interpretation and use of FRAX in clinical practice. Osteoporosis International 2011; 22: 2395-2411. doi: 10.1007/ s00198-011-1713-z.
  • 25. Delmas PD, van de Langerijt L, Watts NB, Eastell R, Genant H et al. Underdiagnosis of vertebral fractures is a worldwide problem: the IMPACT study. Journal of Bone & Mineral Research 2005; 20: 557-563. doi: 10.1359/JBMR.041214
  • 26- Gehlbach SH, Bigelow C, Heimisdottir M, May S, Walker M et al. Recognition of vertebral fracture in a clinical setting. Osteoporosis International 2000; 11:577-582. doi: 10.1007/ s001980070078
  • 27. Camacho PM, Petak SM, Binkley N, Clarke BL, Harris AT et al. American Association of Clinical Endocrinologists/American College of Endocrinology Clinical Practice Guidelines for the diagnosis and treatment of pstmenopausal osteoporosis. Endocrine Practice 2016; 22 (9): 1111-1118. doi: 10.4158/ EP161435.
  • 28. Lenski M, Büser N, Scherer S. Concomitant and previous osteoporotic vertebral fractures. Acta Orthopaedica 2017; 88: 2, 192-197. doi: 10.1080/17453674.2016.1273644.
  • 29. Lems WF, Raterman HG. Critical issues and current challenges in osteoporosis and fracture prevention. An overview of unmet needs. Therapeutic Advances in Musculoskeletal Disease 2017; 9 (12): 299-316. doi: 10.1177/1759720X17732562.
  • 30. Kammerlander C, Zegg M, Schmid R, Gosch M, Luger TJ, Blauth M. Fragility fractures requiring special consideration: vertebral fractures. Clinics in Geriatric Medicine 2014; 30 (2): 361-372. doi: 10.1016/j.cger.2014.01.011.
  • 31. Kanis JA, Harvey NC, McCloskey E, Bruyère O, Veronese N et al. Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures. Osteoporosis International 2020; 31:1-12. doi: 10.1007/s00198-019-05176-3.
  • 32. Eastell R, Rosen CJ, Black DM, Cheung AM, Murad HM et al. Pharmacological management of osteoporosis in postmenopausal women: an endocrine society* clinical practice guideline. The Journal of Clinical Endocrinololgy and Metabolism 2019, 104 (5): 1595-1622. doi: 10.1210/jc.2019- 00221.
  • 33. Hirsch JA, Beall DP, Chambers MR, Andreshak TG, Brook AL et al. Management of vertebral fragility fractures: a clinical care pathway developed by a multispecialty panel using the RAND/UCLA appropriateness method. The Spine Journal 2018; 18: 2152-2161. doi: 10.1016/j.spinee.2018.07.025
  • 34. Longo UG, Loppini M, Denaro L, Maffulli N, Denaro V. Conservative management of patients with an osteoporotic vertebral fracture: a review of the literature. The Journal of Bone and Joint Surgery 2012; 94 (2): 152-157. doi: 10.1302/0301-620X.94B2.26894
  • 35. Curtis EM, Moon RJ, Harvey NC, Cooper C. The impact of fragility fracture and approaches to osteoporosis risk assessment worldwide. Bone 2017; 104:29-38. doi: 10.1016/j. bone.2017.01.024
  • 36. Sànchez-Riera L, Wilson N. Fragility fractures & their impact on older people. Best Practice and Research Clinal Rheumatology 2017; 31 (2): 169-191. doi: 10.1016/j.berh.2017.10.001.
  • 37. Gates M, Pillay J, Thériault G, Limburg H, Grad R. et al. Screening to prevent fragility fractures among adults 40 years and older in primary care: protocol for a systematic review. Systematic Reviews 2019; 8: 216. doi:10.1186/s13643-019- 1094-5
APA Gokce Kutsal F, Korkmaz G (2021). Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. , 393 - 399. 10.3906/sag-2005-315
Chicago Gokce Kutsal F. Yesim,Korkmaz Gizem Olgu Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. (2021): 393 - 399. 10.3906/sag-2005-315
MLA Gokce Kutsal F. Yesim,Korkmaz Gizem Olgu Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. , 2021, ss.393 - 399. 10.3906/sag-2005-315
AMA Gokce Kutsal F,Korkmaz G Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. . 2021; 393 - 399. 10.3906/sag-2005-315
Vancouver Gokce Kutsal F,Korkmaz G Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. . 2021; 393 - 399. 10.3906/sag-2005-315
IEEE Gokce Kutsal F,Korkmaz G "Vertebral compression fractures: Still an unpredictable aspect of osteoporosis." , ss.393 - 399, 2021. 10.3906/sag-2005-315
ISNAD Gokce Kutsal, F. Yesim - Korkmaz, Gizem Olgu. "Vertebral compression fractures: Still an unpredictable aspect of osteoporosis". (2021), 393-399. https://doi.org/10.3906/sag-2005-315
APA Gokce Kutsal F, Korkmaz G (2021). Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. Turkish Journal of Medical Sciences, 51(2), 393 - 399. 10.3906/sag-2005-315
Chicago Gokce Kutsal F. Yesim,Korkmaz Gizem Olgu Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. Turkish Journal of Medical Sciences 51, no.2 (2021): 393 - 399. 10.3906/sag-2005-315
MLA Gokce Kutsal F. Yesim,Korkmaz Gizem Olgu Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. Turkish Journal of Medical Sciences, vol.51, no.2, 2021, ss.393 - 399. 10.3906/sag-2005-315
AMA Gokce Kutsal F,Korkmaz G Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. Turkish Journal of Medical Sciences. 2021; 51(2): 393 - 399. 10.3906/sag-2005-315
Vancouver Gokce Kutsal F,Korkmaz G Vertebral compression fractures: Still an unpredictable aspect of osteoporosis. Turkish Journal of Medical Sciences. 2021; 51(2): 393 - 399. 10.3906/sag-2005-315
IEEE Gokce Kutsal F,Korkmaz G "Vertebral compression fractures: Still an unpredictable aspect of osteoporosis." Turkish Journal of Medical Sciences, 51, ss.393 - 399, 2021. 10.3906/sag-2005-315
ISNAD Gokce Kutsal, F. Yesim - Korkmaz, Gizem Olgu. "Vertebral compression fractures: Still an unpredictable aspect of osteoporosis". Turkish Journal of Medical Sciences 51/2 (2021), 393-399. https://doi.org/10.3906/sag-2005-315