Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension

TURAN, Oguzhan Ekrem; Kınık, Mustafa; Yilmaz, Ahmet Seyda; Özyıldız, Ali Gökhan; Çetin, Mustafa; OZER, SAVAS; Aslan, Mehmet Gökhan; Yücekul, Burcu

doi:10.14744/nci.2020.23334

Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension

Savaş ÖZER, (Recep Tayyip Erdoğan Üniversitesi Eğitim ve Araştırma Hastanesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Burcu Yucekul, (Sağlık Bilimleri Üniversitesi Haseki Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Ahmet Seyda YILMAZ, (Recep Tayyip Erdoğan Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Ali Gökhan ÖZYILDIZ, (Recep Tayyip Erdoğan Üniversitesi Eğitim ve Araştırma Hastanesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Mustafa Kinik, (Recep Tayyip Erdoğan Üniversitesi Eğitim ve Araştırma Hastanesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Oğuzhan Ekrem TURAN, (Karadeniz Teknik Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Trabzon, Türkiye)

Mehmet Gökhan ASLAN, (Recep Tayyip Erdoğan Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, Rize, Türkiye)

Mustafa ÇETİN (Recep Tayyip Erdoğan Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

İstanbul Kuzey Klinikleri

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Yıl: 2021 Cilt: 8 Sayı: 4 Sayfa Aralığı: 365 - 370 Metin Dili: İngilizce DOI: 10.14744/nci.2020.23334 İndeks Tarihi: 21-01-2022

Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension

Öz:

OBJECTIVE: Hypertensive retinopathy develops based on endothelial dysfunction, inflammation, and atherosclerosis. Epicardial fat secretes various cytokines associated with endothelial dysfunction, oxidative stress, inflammation, and atherosclerosis. We aimed to evaluate whether epicardial adipose tissue (EAT) thickness is a marker for retinopathy in newly diagnosed hypertensive patients. METHODS: A total of 73 newly diagnosed hypertension (HT) patients were included in the study. Transthoracic echocardiography (TTE) was used to measure EAT thickness. To evaluate the presence of retinopathy in HT patients, hypertensive retinopathy staging was performed by ophthalmologists, according to Scheie classification. RESULTS: Retinopathy was detected in 27 (37.0%) of 73 patients. EAT thickness in HT patients with retinopathy was higher than the group without retinopathy (5.07±1.45 mm vs. 4.19±1.20 mm, p=0.007). Low-density lipoprotein cholesterol (LDL-C) levels in HT patients with retinopathy were higher than the group without retinopathy (162.4±41.2 mg/dl vs. 138.1±35.6 mg/dl, p=0.010). As a result of the regression analysis, LDL-C (OR=1.016, 95% CI 1.001–1.031, p=0.043) and EAT thickness (OR=1.674, 95% CI 1.069–2.626, p=0.043) were the independent predictors of retinopathy. CONCLUSION: Increased EAT thickness is associated with the presence of retinopathy in hypertensive patients.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	OZER S, Yücekul B, Yilmaz A, Özyıldız A, Kınık M, TURAN O, Aslan M, Çetin M (2021). Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. , 365 - 370. 10.14744/nci.2020.23334
Chicago	OZER SAVAS,Yücekul Burcu,Yilmaz Ahmet Seyda,Özyıldız Ali Gökhan,Kınık Mustafa,TURAN Oguzhan Ekrem,Aslan Mehmet Gökhan,Çetin Mustafa Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. (2021): 365 - 370. 10.14744/nci.2020.23334
MLA	OZER SAVAS,Yücekul Burcu,Yilmaz Ahmet Seyda,Özyıldız Ali Gökhan,Kınık Mustafa,TURAN Oguzhan Ekrem,Aslan Mehmet Gökhan,Çetin Mustafa Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. , 2021, ss.365 - 370. 10.14744/nci.2020.23334
AMA	OZER S,Yücekul B,Yilmaz A,Özyıldız A,Kınık M,TURAN O,Aslan M,Çetin M Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. . 2021; 365 - 370. 10.14744/nci.2020.23334
Vancouver	OZER S,Yücekul B,Yilmaz A,Özyıldız A,Kınık M,TURAN O,Aslan M,Çetin M Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. . 2021; 365 - 370. 10.14744/nci.2020.23334
IEEE	OZER S,Yücekul B,Yilmaz A,Özyıldız A,Kınık M,TURAN O,Aslan M,Çetin M "Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension." , ss.365 - 370, 2021. 10.14744/nci.2020.23334
ISNAD	OZER, SAVAS vd. "Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension". (2021), 365-370. https://doi.org/10.14744/nci.2020.23334

APA	OZER S, Yücekul B, Yilmaz A, Özyıldız A, Kınık M, TURAN O, Aslan M, Çetin M (2021). Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. İstanbul Kuzey Klinikleri, 8(4), 365 - 370. 10.14744/nci.2020.23334
Chicago	OZER SAVAS,Yücekul Burcu,Yilmaz Ahmet Seyda,Özyıldız Ali Gökhan,Kınık Mustafa,TURAN Oguzhan Ekrem,Aslan Mehmet Gökhan,Çetin Mustafa Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. İstanbul Kuzey Klinikleri 8, no.4 (2021): 365 - 370. 10.14744/nci.2020.23334
MLA	OZER SAVAS,Yücekul Burcu,Yilmaz Ahmet Seyda,Özyıldız Ali Gökhan,Kınık Mustafa,TURAN Oguzhan Ekrem,Aslan Mehmet Gökhan,Çetin Mustafa Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. İstanbul Kuzey Klinikleri, vol.8, no.4, 2021, ss.365 - 370. 10.14744/nci.2020.23334
AMA	OZER S,Yücekul B,Yilmaz A,Özyıldız A,Kınık M,TURAN O,Aslan M,Çetin M Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. İstanbul Kuzey Klinikleri. 2021; 8(4): 365 - 370. 10.14744/nci.2020.23334
Vancouver	OZER S,Yücekul B,Yilmaz A,Özyıldız A,Kınık M,TURAN O,Aslan M,Çetin M Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension. İstanbul Kuzey Klinikleri. 2021; 8(4): 365 - 370. 10.14744/nci.2020.23334
IEEE	OZER S,Yücekul B,Yilmaz A,Özyıldız A,Kınık M,TURAN O,Aslan M,Çetin M "Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension." İstanbul Kuzey Klinikleri, 8, ss.365 - 370, 2021. 10.14744/nci.2020.23334
ISNAD	OZER, SAVAS vd. "Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension". İstanbul Kuzey Klinikleri 8/4 (2021), 365-370. https://doi.org/10.14744/nci.2020.23334