TY  - JOUR
TI  - Epicardial fat thickness is associated with retinopathy in patients with newly diagnosed hypertension
AB  - OBJECTIVE: Hypertensive retinopathy develops based on endothelial dysfunction, inflammation, and atherosclerosis. Epicardial fat secretes various cytokines associated with endothelial dysfunction, oxidative stress, inflammation, and atherosclerosis. We aimed to evaluate whether epicardial adipose tissue (EAT) thickness is a marker for retinopathy in newly diagnosed hypertensive patients. METHODS: A total of 73 newly diagnosed hypertension (HT) patients were included in the study. Transthoracic echocardiography (TTE) was used to measure EAT thickness. To evaluate the presence of retinopathy in HT patients, hypertensive retinopathy staging was performed by ophthalmologists, according to Scheie classification. RESULTS: Retinopathy was detected in 27 (37.0%) of 73 patients. EAT thickness in HT patients with retinopathy was higher than the group without retinopathy (5.07±1.45 mm vs. 4.19±1.20 mm, p=0.007). Low-density lipoprotein cholesterol (LDL-C) levels in HT patients with retinopathy were higher than the group without retinopathy (162.4±41.2 mg/dl vs. 138.1±35.6 mg/dl, p=0.010). As a result of the regression analysis, LDL-C (OR=1.016, 95% CI 1.001–1.031, p=0.043) and EAT thickness (OR=1.674, 95% CI 1.069–2.626, p=0.043) were the independent predictors of retinopathy. CONCLUSION: Increased EAT thickness is associated with the presence of retinopathy in hypertensive patients.
AU  - TURAN, Oguzhan Ekrem
AU  - Kınık, Mustafa
AU  - Yilmaz, Ahmet Seyda
AU  - Özyıldız, Ali Gökhan
AU  - Çetin, Mustafa
AU  - OZER, SAVAS
AU  - Aslan, Mehmet Gökhan
AU  - Yücekul, Burcu
DO  - 10.14744/nci.2020.23334
PY  - 2021
JO  - İstanbul Kuzey Klinikleri
VL  - 8
IS  - 4
SN  - 2148-4902
SP  - 365
EP  - 370
DB  - TRDizin
UR  - http://search/yayin/detay/484134
ER  -