Perspectives for immune plasma treatment of COVID-19
Yıl: 2021 Cilt: 51 Sayı: 1 Sayfa Aralığı: 1 - 9 Metin Dili: İngilizce DOI: 10.3906/sag-2005-410 İndeks Tarihi: 25-01-2022
Perspectives for immune plasma treatment of COVID-19
Öz: Background/aim: The SARS-CoV-2 infection was declared as a pandemic by the World Health Organization (WHO) on March 11, 2020, and the death toll from COVID-19, which is the disease caused by SARS-CoV-2, has already surpassed that of many previous epidemics. A wide variety of treatment options are being considered for COVID-19, but there is still no definitive treatment or vaccine. This study aims to explain the background of convalescent plasma (CP) treatment and its relations with COVID-19 immunity, to define ideal treatment procedures, and to reveal present and future perspectives in the light of the rapidly growing data. Immunological basis of COVID-19-associated immune response and convalescent plasma as a treatment option: Since it has been shown that the impaired immune response of the host is one of the most important factors that increase the severity of the infection, treatment strategies to suppress aberrant immune activation are currently being considered. CP, which is derived from recently recovered patients and contains neutralizing antibodies and many other immunemodulatory substances, seems to be the most convenient strategy to restore normal immune function considering the fast spreading nature of the ongoing pandemic. Conclusion: Even though mechanisms of action of plasma therapy are not fully delineated, it was shown that it could lead to a reduction in mortality since other alternatives such as monoclonal antibodies or SARS-CoV-2 hyperimmunoglobulin require much more time and effort to be developed.Key words: COVID-19, pandemic, convalescent plasma
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Sayınalp B, Çınar O, Haznedaroglu I (2021). Perspectives for immune plasma treatment of COVID-19. , 1 - 9. 10.3906/sag-2005-410 |
| Chicago | Sayınalp Başak,Çınar Olgu Erkin,Haznedaroglu Ibrahim C. Perspectives for immune plasma treatment of COVID-19. (2021): 1 - 9. 10.3906/sag-2005-410 |
| MLA | Sayınalp Başak,Çınar Olgu Erkin,Haznedaroglu Ibrahim C. Perspectives for immune plasma treatment of COVID-19. , 2021, ss.1 - 9. 10.3906/sag-2005-410 |
| AMA | Sayınalp B,Çınar O,Haznedaroglu I Perspectives for immune plasma treatment of COVID-19. . 2021; 1 - 9. 10.3906/sag-2005-410 |
| Vancouver | Sayınalp B,Çınar O,Haznedaroglu I Perspectives for immune plasma treatment of COVID-19. . 2021; 1 - 9. 10.3906/sag-2005-410 |
| IEEE | Sayınalp B,Çınar O,Haznedaroglu I "Perspectives for immune plasma treatment of COVID-19." , ss.1 - 9, 2021. 10.3906/sag-2005-410 |
| ISNAD | Sayınalp, Başak vd. "Perspectives for immune plasma treatment of COVID-19". (2021), 1-9. https://doi.org/10.3906/sag-2005-410 |
| APA | Sayınalp B, Çınar O, Haznedaroglu I (2021). Perspectives for immune plasma treatment of COVID-19. Turkish Journal of Medical Sciences, 51(1), 1 - 9. 10.3906/sag-2005-410 |
| Chicago | Sayınalp Başak,Çınar Olgu Erkin,Haznedaroglu Ibrahim C. Perspectives for immune plasma treatment of COVID-19. Turkish Journal of Medical Sciences 51, no.1 (2021): 1 - 9. 10.3906/sag-2005-410 |
| MLA | Sayınalp Başak,Çınar Olgu Erkin,Haznedaroglu Ibrahim C. Perspectives for immune plasma treatment of COVID-19. Turkish Journal of Medical Sciences, vol.51, no.1, 2021, ss.1 - 9. 10.3906/sag-2005-410 |
| AMA | Sayınalp B,Çınar O,Haznedaroglu I Perspectives for immune plasma treatment of COVID-19. Turkish Journal of Medical Sciences. 2021; 51(1): 1 - 9. 10.3906/sag-2005-410 |
| Vancouver | Sayınalp B,Çınar O,Haznedaroglu I Perspectives for immune plasma treatment of COVID-19. Turkish Journal of Medical Sciences. 2021; 51(1): 1 - 9. 10.3906/sag-2005-410 |
| IEEE | Sayınalp B,Çınar O,Haznedaroglu I "Perspectives for immune plasma treatment of COVID-19." Turkish Journal of Medical Sciences, 51, ss.1 - 9, 2021. 10.3906/sag-2005-410 |
| ISNAD | Sayınalp, Başak vd. "Perspectives for immune plasma treatment of COVID-19". Turkish Journal of Medical Sciences 51/1 (2021), 1-9. https://doi.org/10.3906/sag-2005-410 |
