Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation
Yıl: 2021 Cilt: 25 Sayı: 11 Sayfa Aralığı: 789 - 795 Metin Dili: İngilizce DOI: 10.5152/AnatolJCardiol.2021.03982 İndeks Tarihi: 06-02-2022
Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation
Öz: Objective: To evaluate the prognostic value of preprocedural CHA2DS2-VASc [congestive heart failure, hypertension, age ≥75 years (doubled), diabetes mellitus, previous stroke or transient ischemic attack (TIA) (doubled), vascular disease, age 65-74 years, female gender] score in predicting high SYNTAX (Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery) score and in-hospital mortality for non-atrial fibrillation (AF) patients presenting with non-ST elevation myocardial infarction (NSTEMI). The CHA2DS2-VASc score used to determine thromboembolic risks in AF was recently reported to predict major adverse clinical outcomes in patients with the acute coronary syndrome, irrespective of AF. Methods: A total of 906 patients with a diagnosis of NSTEMI who underwent coronary angiography were retrospectively enrolled and divided into three groups according to their SYNTAX scores (low, intermediate, and high). The CHA2DS2-VASc score of each patient was calculated. Results: SYNTAX score had a significant positive correlation with the CHA2DS2-VASc score (r=0.320; p<0.001) in the Spearman correlation analysis. The CHA2DS2-VASc score [Odds ratio, 1.445; 95% confidence interval (CI), 1.268-1.648, p<0.001], left ventricular ejection fraction, creatinine, C-reactive protein, and high-density and low-density lipoprotein cholesterol levels were demonstrated to be independent predictors of high SYNTAX score. The CHA2DS2-VASc score [Hazard ratio (HR), 1.867; 95% CI: 1.462-2.384; p<0.001], the SYNTAX score (HR, 1.049; p=0.003), and age (HR, 1.057; p=0.002) were independently associated with higher risk of in-hospital mortality in a multiple Cox-regression model. Kaplan-Meier survival curves stratified by the CHA2DS2-VASc score (<4 vs. ≥4) also showed that higher CHA2DS2-VASc scores were associated with higher in-hospital mortality. Conclusions: In non-AF patients with NSTEMI, CHA2DS2-VASc and SYNTAX scores are useful for prognosis assessment and can be used to identify patients at higher risk for in-hospital mortality.
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| APA | Akboga M, Yilmaz S, YALÇIN M (2021). Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. , 789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| Chicago | Akboga Mehmet Kadri,Yilmaz Samet,YALÇIN MEHMET RIDVAN Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. (2021): 789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| MLA | Akboga Mehmet Kadri,Yilmaz Samet,YALÇIN MEHMET RIDVAN Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. , 2021, ss.789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| AMA | Akboga M,Yilmaz S,YALÇIN M Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. . 2021; 789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| Vancouver | Akboga M,Yilmaz S,YALÇIN M Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. . 2021; 789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| IEEE | Akboga M,Yilmaz S,YALÇIN M "Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation." , ss.789 - 795, 2021. 10.5152/AnatolJCardiol.2021.03982 |
| ISNAD | Akboga, Mehmet Kadri vd. "Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation". (2021), 789-795. https://doi.org/10.5152/AnatolJCardiol.2021.03982 |
| APA | Akboga M, Yilmaz S, YALÇIN M (2021). Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. The Anatolian Journal of Cardiology, 25(11), 789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| Chicago | Akboga Mehmet Kadri,Yilmaz Samet,YALÇIN MEHMET RIDVAN Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. The Anatolian Journal of Cardiology 25, no.11 (2021): 789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| MLA | Akboga Mehmet Kadri,Yilmaz Samet,YALÇIN MEHMET RIDVAN Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. The Anatolian Journal of Cardiology, vol.25, no.11, 2021, ss.789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| AMA | Akboga M,Yilmaz S,YALÇIN M Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. The Anatolian Journal of Cardiology. 2021; 25(11): 789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| Vancouver | Akboga M,Yilmaz S,YALÇIN M Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation. The Anatolian Journal of Cardiology. 2021; 25(11): 789 - 795. 10.5152/AnatolJCardiol.2021.03982 |
| IEEE | Akboga M,Yilmaz S,YALÇIN M "Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation." The Anatolian Journal of Cardiology, 25, ss.789 - 795, 2021. 10.5152/AnatolJCardiol.2021.03982 |
| ISNAD | Akboga, Mehmet Kadri vd. "Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation". The Anatolian Journal of Cardiology 25/11 (2021), 789-795. https://doi.org/10.5152/AnatolJCardiol.2021.03982 |
