Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer
Yıl: 2021 Cilt: 13 Sayı: 2 Sayfa Aralığı: 116 - 122 Metin Dili: İngilizce DOI: 10.4274/iksstd.2021.71224 İndeks Tarihi: 06-02-2022
Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer
Öz: Objective: Gastric cancer is the fourth most common cause of death worldwide and the second most common cause of cancer-related deaths. Minimally invasive surgery now offers many advantages to both patients and surgeons all over the world. In our study, we presented our laparoscopic experiences in locally advanced gastric cancer (LAGC) surgery. Method: Data of patients who underwent gastrectomy for LAGC in our clinic between January 2010 and January 2020 were retrospectively analyzed. Results: Gastrectomy was performed on 288 patients with LAGC. Although laparoscopic surgery was conducted on 96 patients (33.3%), open surgery was performed on 192 (66.7%) patients. The mean operation time was 122.96 ± 44.06 (60-300) min. There was no statistically significant difference between the two groups in terms of anastomotic leakage (p = 0.724). The mean length of stay was 12.54 days in patients undergoing open surgery and 9.36 days in those undergoing laparoscopic surgery, with a statistically significant difference between the two groups (p < 0.001). Conclusion: Although the learning curve is long and requires experience, we think that laparoscopic surgery is feasible in LAGC, as in early-stage gastric cancer.
Anahtar Kelime: Lokal İleri Mide kanserinde Laparoskopik Gastrektomi Kısa ve Uzun Dönem Sonuçlarımız
Öz: Amaç: Mide kanseri tüm dünyada en sık görülen dördüncü, kansere bağlı ölümlerin en sık ikinci nedenidir. Tüm dünyada artık minimal invaziv cerrahi hem hastalara hem de cerrahlara birçok avantaj sunmaktadır. Çalışmamızda lokal ileri mide kanseri (LİMK) cerrahisinde laparoskopik deneyimlerimizi sunduk. Yöntem: Ocak 2010 - Ocak 2020 tarihleri arasında kliniğimizde LİMK nedeniyle gastrektomi yapılan hastaların verileri retrospektif olarak incelendi. Bulgular: LİMK nedeniyle 288 hastaya gastrektomi yapıldı. Hastaların 92’si (%31,9) kadın 196’sı (%68,1) erkekti. Hastaların 96’sına (%33,3) laparoskopik cerrahi yapılırken 192’sine (%66,7) ise açık cerrahi uygulanmıştır. Operasyon süresi ortalama 122,96 ± 44,06 (60-300) dakikaydı. Anastomoz kaçağı açısından iki grup arasında istatistiksel anlamlı fark bulunmamıştır (p=0,724). Yatış süresi bakımından açık cerrahide ortalama 12,54 gün iken laparoskopik cerrahide 9,36 gün olup iki grup arasında istatistiksel anlamlı fark gösterilmiştir (p<0,001). Sonuç: Sonuç olarak öğrenme eğrisi uzun ve deneyim gerektirse de erken evre mide kanserinde olduğu gibi LİMK’de laparoskopik cerrahinin uygulanabilir olduğunu düşünüyoruz.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. Kamangar F, Dores GM, Anderson WF. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. Journal of clinical oncology. 2006;24(14):2137-50.
- 2. Mukherjee S, Hurt CN, Bridgewater J, Falk S, Cummins S, Wasan H, et al. Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial. The lancet oncology. 2013;14(4):317-26.
- 3. Sasako M, Sano T, Yamamoto S, Kurokawa Y, Nashimoto A, Kurita A, et al. D2 lymphadenectomy alone or with para-aortic nodal dissection for gastric cancer. New England Journal of Medicine. 2008;359(5):453-62.
- 4. Songun I, Putter H, Kranenbarg EM-K, Sasako M, van de Velde CJ. Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial. The lancet oncology. 2010;11(5):439-49.
- 5. Kitano S, Iso Y, Moriyama M, Sugimachi K. Laparoscopy-assisted Billroth I gastrectomy. Surgical Laparoscopy Endoscopy & Percutaneous Techniques. 1994;4(2):146-8.
- 6. Bracale U, Pignata G, Lirici MM, Hüscher CG, Pugliese R, Sgroi G, et al. Laparoscopic gastrectomies for cancer: The ACOI-IHTSC national guidelines. Minimally Invasive Therapy & Allied Technologies. 2012;21(5):313-9.
- 7. Chen X-Z, Hu J-K, Yang K, Wang L, Lu Q-C. Short-term evaluation of laparoscopy-assisted distal gastrectomy for predictive early gastric cancer: a meta-analysis of randomized controlled trials. Surgical Laparoscopy Endoscopy & Percutaneous Techniques. 2009;19(4):277- 84.
- 8. Yasunaga H, Horiguchi H, Kuwabara K, Matsuda S, Fushimi K, Hashimoto H, et al. Outcomes after laparoscopic or open distal gastrectomy for early-stage gastric cancer: a propensity-matched analysis. Annals of surgery. 2013;257(4):640-6.
- 9. Best LM, Mughal M, Gurusamy KS. Laparoscopic versus open gastrectomy for gastric cancer. Cochrane Database of Systematic Reviews. 2016(3).
- 10. Nam BH, Kim Y-W, Reim D, Eom BW, Yu WS, Park YK, et al. Laparoscopy assisted versus open distal gastrectomy with D2 lymph node dissection for advanced gastric cancer: design and rationale of a phase II randomized controlled multicenter trial (COACT 1001). Journal of gastric cancer. 2013;13(3):164-71.
- 11. Association JGC. Japanese gastric cancer treatment guidelines 2010 (ver. 3). Gastric cancer. 2011;14(2):113-23.
- 12. Barreto SG, Sirohi B. Why should we perform a D2 lymphadenectomy in gastric cancer? : Future Medicine; 2017.
- 13. Kim W, Kim H, Han S, Kim M, Hyung W, Ryu S, et al. Korean Laparoendoscopic Gastrointestinal Surgery Study (KLASS) Group. Decreased morbidity of laparoscopic distal gastrectomy compared with open distal gastrectomy for stage I gastric cancer: short-term outcomes from a multicenter randomized controlled trial (KLASS-01). Ann Surg. 2016;263(1):28-35.
- 14. Kitano S, Shiraishi N, Uyama I, Sugihara K, Tanigawa N, Group JLSS. A multicenter study on oncologic outcome of laparoscopic gastrectomy for early cancer in Japan. Annals of surgery. 2007;245(1):68.
- 15. Sasako M. Is there role for laparoscopic gastrectomy for advanced gastric cancer. European Journal of Surgical Oncology. 2017;43(6):965- 7.
- 16. Ure B, Niewold T, Bax N, Ham M, Van Der Zee D, Essen G. Peritoneal, systemic, and distant organ inflammatory responses are reduced by a laparoscopic approach and carbon dioxide vs air. Surgical Endoscopy and Other Interventional Techniques. 2002;16(5):836-42.
- 17. Park YK, Yoon Ã, Kim Y-w, Park Y, Ryu KW, Lee Y-j, et al. Laparoscopyassisted versus Open D2 Distal Gastrectomy for.
- 18. Nakauchi M, Suda K, Nakamura K, Shibasaki S, Kikuchi K, Nakamura T, et al. Laparoscopic subtotal gastrectomy for advanced gastric cancer: technical aspects and surgical, nutritional and oncological outcomes. Surgical Endoscopy. 2017;31(11):4631-40.
- 19. Memon MA, Khan S, Yunus RM, Barr R, Memon B. Meta-analysis of laparoscopic and open distal gastrectomy for gastric carcinoma. Surgical endoscopy. 2008;22(8):1781-9.
- 20. Tokunaga M, Hiki N, Fukunaga T, Nohara K, Katayama H, Akashi Y, et al. Laparoscopy-assisted distal gastrectomy with D2 lymph node dissection following standardization—a preliminary study. Journal of Gastrointestinal Surgery. 2009;13(6):1058-63.
- 21. Sato H, Shimada M, Kurita N, Iwata T, Nishioka M, Morimoto S, et al. Comparison of long-term prognosis of laparoscopy-assisted gastrectomy and conventional open gastrectomy with special reference to D2 lymph node dissection. Surgical endoscopy. 2012;26(8):2240-6.
- 22. Nakauchi M, Suda K, Kadoya S, Inaba K, Ishida Y, Uyama I. Technical aspects and short-and long-term outcomes of totally laparoscopic total gastrectomy for advanced gastric cancer: a single-institution retrospective study. Surgical endoscopy. 2016;30(10):4632-9.
- 23. Qiu J, Pankaj P, Jiang H, Zeng Y, Wu H. Laparoscopy versus open distal gastrectomy for advanced gastric cancer: a systematic review and metaanalysis. Surgical Laparoscopy Endoscopy & Percutaneous Techniques. 2013;23(1):1-7.
- 24. Choi YY, Bae JM, An JY, Hyung WJ, Noh SH. Laparoscopic gastrectomy for advanced gastric cancer: Are the long-term results comparable with conventional open gastrectomy? A systematic review and metaanalysis. Journal of surgical oncology. 2013;108(8):550-6.
- 25. Quan Y, Huang A, Ye M, Xu M, Zhuang B, Zhang P, et al. Comparison of laparoscopic versus open gastrectomy for advanced gastric cancer: an updated meta-analysis. Gastric Cancer. 2016;19(3):939-50.
| APA | Culcu S, Yüksel C, Demirci S, Ünal A, Bayar S, Gojayev A (2021). Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. , 116 - 122. 10.4274/iksstd.2021.71224 |
| Chicago | Culcu Serdar,Yüksel Cemil,Demirci Salim,Ünal Ali Ekrem,Bayar Sancar,Gojayev Afig Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. (2021): 116 - 122. 10.4274/iksstd.2021.71224 |
| MLA | Culcu Serdar,Yüksel Cemil,Demirci Salim,Ünal Ali Ekrem,Bayar Sancar,Gojayev Afig Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. , 2021, ss.116 - 122. 10.4274/iksstd.2021.71224 |
| AMA | Culcu S,Yüksel C,Demirci S,Ünal A,Bayar S,Gojayev A Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. . 2021; 116 - 122. 10.4274/iksstd.2021.71224 |
| Vancouver | Culcu S,Yüksel C,Demirci S,Ünal A,Bayar S,Gojayev A Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. . 2021; 116 - 122. 10.4274/iksstd.2021.71224 |
| IEEE | Culcu S,Yüksel C,Demirci S,Ünal A,Bayar S,Gojayev A "Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer." , ss.116 - 122, 2021. 10.4274/iksstd.2021.71224 |
| ISNAD | Culcu, Serdar vd. "Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer". (2021), 116-122. https://doi.org/10.4274/iksstd.2021.71224 |
| APA | Culcu S, Yüksel C, Demirci S, Ünal A, Bayar S, Gojayev A (2021). Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. İstanbul Kanuni Sultan Süleyman Tıp Dergisi, 13(2), 116 - 122. 10.4274/iksstd.2021.71224 |
| Chicago | Culcu Serdar,Yüksel Cemil,Demirci Salim,Ünal Ali Ekrem,Bayar Sancar,Gojayev Afig Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. İstanbul Kanuni Sultan Süleyman Tıp Dergisi 13, no.2 (2021): 116 - 122. 10.4274/iksstd.2021.71224 |
| MLA | Culcu Serdar,Yüksel Cemil,Demirci Salim,Ünal Ali Ekrem,Bayar Sancar,Gojayev Afig Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. İstanbul Kanuni Sultan Süleyman Tıp Dergisi, vol.13, no.2, 2021, ss.116 - 122. 10.4274/iksstd.2021.71224 |
| AMA | Culcu S,Yüksel C,Demirci S,Ünal A,Bayar S,Gojayev A Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. İstanbul Kanuni Sultan Süleyman Tıp Dergisi. 2021; 13(2): 116 - 122. 10.4274/iksstd.2021.71224 |
| Vancouver | Culcu S,Yüksel C,Demirci S,Ünal A,Bayar S,Gojayev A Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer. İstanbul Kanuni Sultan Süleyman Tıp Dergisi. 2021; 13(2): 116 - 122. 10.4274/iksstd.2021.71224 |
| IEEE | Culcu S,Yüksel C,Demirci S,Ünal A,Bayar S,Gojayev A "Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer." İstanbul Kanuni Sultan Süleyman Tıp Dergisi, 13, ss.116 - 122, 2021. 10.4274/iksstd.2021.71224 |
| ISNAD | Culcu, Serdar vd. "Our Short- and Long-Term Results of Laparoscopic Gastrectomy in Locally Advanced Gastric Cancer". İstanbul Kanuni Sultan Süleyman Tıp Dergisi 13/2 (2021), 116-122. https://doi.org/10.4274/iksstd.2021.71224 |
