TY  - JOUR
TI  - Electrochemical Detection of Antioxidant Activities of 1,4-Dihydropyridine Derivatives
AB  - Antioxidant is a molecule which retards the autooxidation of fats and oils. Antioxidants block the oxidation process which can cause damage to many cells in body helping to prevent diseases. Therefore, the importance of antioxidant is in increasing demand. So far many attempts have been carried out for developing to detect antioxidant activities. Among various analytical techniques, electrochemistry has been a more appropriate way to determine antioxidant activity due to its ease of use and short-lasting application. In this study, it was aimed to determine antioxidant activities of recently synthesized condensed 1,4-dihydropyridine derivatives using disposable pencil graphite electrode. Cyclic voltammetry technique was used to determine oxidation potential value, and also differential pulse voltammetry technique was used to determine reduction potential values of the derivatives. To verify our results, nifedipine was used as a reference drug and conventional antioxidant activities were also used as a basis for comparison.
AU  - ŞİMŞEK, Rahime
AU  - GÜNDÜZ, Miyase Gözde
AU  - BOLAT, Gülçin
AU  - SÜRÜCÜ, Özge
AU  - Kuralay, Filiz
AU  - KHOULY, Ahmad El
AU  - safak, cihat
AU  - ABACI, Serdar
DO  - 10.15671/HJBC.2016.134
PY  - 2016
JO  - Hacettepe Journal of Biology and Chemistry
VL  - 44
IS  - 4
SN  - 1303-5002
SP  - 535
EP  - 548
DB  - TRDizin
UR  - http://search/yayin/detay/488531
ER  -