Introduction: The aim of this study is to examine the story, clinical findings, initial computed tomography (CT) findings, and reverse transcription–polymerase chain reaction (RT-PCR) results and to evaluate the consistency of this data. Methods: This is a multi-center retrospective study and out of patients aged 18 and over who were evaluated for Corona- virus disease 2019 (COVID-19) in the emergency department between April 01, 2020 and May 01, 2020. Data regarding the patients such as age, gender, comorbidity, COVID-19 contact, symptoms, vital findings, laboratory parameters, CT findings, hospitalization status, and case fatality rate (CFR) were examined. Results: About 62.4% of 687 patients were male, the mean age was 49.7. About 49.9% of patients had at least one comorbid- ity. The most common symptoms were fever (61.6%), cough (56.5%), and dyspnea (33.2%). About 33.9% of patients had RT- PCR positivity, 69.9% had CT positivity, and 72.5% had both RT-PCR and CT positivity. Sensitivity of CT was 72.5, its specificity was 31.5%, and its accuracy was 45.5%. Most common CT pattern was pure GGO (47.9%). CFR was 6% and it was significantly higher in both RT-PCR and CT positive patients (p=0.01). According to logistic regression analysis, male gender [p=0.037; odds ratio (OR): 0.385; 95% confidence interval (CI), 0.157–0.943], higher age (p=0.000; OR: 1.068; 95% CI, 1.031–1.106), and comorbidity presence (p=0.008; OR: 5.374; 95% CI, 1.539–7.618) were found to be associated with mortality. Discussion and Conclusion: In our study, we found that using RT-PCR and CT together and supporting them with clinical data were the strongest approach in the diagnosis of COVID-19 cases.