Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis
Yıl: 2021 Cilt: 37 Sayı: 1 Sayfa Aralığı: 1 - 8 Metin Dili: İngilizce DOI: 10.15312/EurasianJVetSci.2021.319 İndeks Tarihi: 10-02-2022
Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis
Öz: Aim: The aim of the present study was to comparison of blood gases, hematological and monitorization parameters in hypotensive and non-hypotensive calves with sepsis and also, determine the probably prognostic variables to prediction mortality. Materials and Methods: Twenty-two calves were met the criteria of sepsis were enrolled in the study. Hypotension was defined as presence of systolic blood pressure (SBP) <90 mmHg and/or mean arterial pressure (MAP) <65mmHg. Results: During study 7 (58%) hypotensive and 4 (40%) non-hypotensive calves died. Clinical findings showed that hypotensive calves had a lower body temperature, SBP and MAP than hypotensive calves. Glucose levels were significantly lower, and RBC and HCT levels were higher in hypotensive calves than non-hypotension calves. Venous pO2 and SO2 were lower and lactate was higher in non-survivor calves than survivor calves. The findings of receiver operating characteristic curve (ROC) showed the area under the curve (AUC) of 0.991 (p=0.000, 95% CI=0.962-1.000), sensitivity of 100% and a specificity of 99% for prediction of mortality at optimum cut off point of 6.7 mmol/L propound the lactate as best prognostic indicator. Conclusion: Mortality rate in hypotensive calves is higher than nonhypotensive calves. Our findings indicated that tissue hypoxia is the strongest determinant of mortality in septic calves. Blood lactate levels with sensitivity of 100% and specificity of %99 at cut-off point of 6.7 mmol/L is the best prognostic indicator to differentiate between survivor and non-survivor calves with sepsis.
Anahtar Kelime: Hipotansif ve hipotansif olmayan sepsisli buzağılarda kan gazları, hemotolojik ve monitarizasyon parametrelerinin karşılaştırılması ve seçilmiş değişkenlerin prognostik öneminin belirlenmesi
Öz: Amaç: Sunulan çalışmada hipotansif ve hipotansif olmayan sepsisli buzağılarda kan gaz, hemogram ve monitorizasyon parametrelerini karşılaştırmak ve mortalite tahmininde olası prognostik değişkenleri belirlemek amaçlanmıştır. Gereç ve Yöntem: Araştırmaya sepsis kriterlerini taşıyan 22 adet buzağı dahil edildi. Hipotansiyon için sistolik kan basıncının (SBP) <90 mmHg ve / veya ortalama arteriyel kan basıncının (MAP) <65 mmHg kriterleri göz önünde bulunduruldu. Bulgular: Çalışma sırasında 7 (%58) hipotansif ve 4 (%40) hipotansif olmayan buzağı öldü. Klinik olarak hipotansif buzağıların vücut ısısı, SBP ve MAP düzeyleri hipotansif olmayanlara göre daha düşüktü. Hipotansif buzağıların glikoz düzeyleri hipotansif olmayan buzağılara göre önemli oranda düşük, RBC ve HCT düzeyleri yüksekti. Ölen buzağıların venöz pO2 ve SO2 düzeyleri hayatta kalan buzağılara göre daha düşük, laktat düzeyleri daha yüksekti. ROC analizi sonucunda; eğri altında kalan alan (AUC) 0,991 (% 95 güven aralığı (Cl): 0.962-1.000; p=0,000), % 100 sensitivite ve % 99 spesifite ile laktat düzeyinin 6,7 mmol/L Cut-off değeri mortalite tahmini açısından en iyi prognostik gösterge olarak bulundu. Öneri: Sonuç olarak, mortalite oranı hipotansif buzağılarda hipotansif olmayan buzağılara göre daha yüksektir. Bulgularımız, septik buzağılarda mortalitenin en güçlü belirleyicisinin doku hipoksisi olduğunu gösterdi. % 100 sensitivite ve % 99 spesifite ile 6.7 mmol/L Cut-off değerinde laktat düzeyleri sepsisli ölen ve hayattta kalan buzağıları ayırt etmede en iyi prognostik göstergedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | NASERI A, İDER M (2021). Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. , 1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| Chicago | NASERI AMIR,İDER Merve Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. (2021): 1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| MLA | NASERI AMIR,İDER Merve Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. , 2021, ss.1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| AMA | NASERI A,İDER M Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. . 2021; 1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| Vancouver | NASERI A,İDER M Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. . 2021; 1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| IEEE | NASERI A,İDER M "Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis." , ss.1 - 8, 2021. 10.15312/EurasianJVetSci.2021.319 |
| ISNAD | NASERI, AMIR - İDER, Merve. "Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis". (2021), 1-8. https://doi.org/10.15312/EurasianJVetSci.2021.319 |
| APA | NASERI A, İDER M (2021). Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. Eurasian Journal of Veterinary Sciences, 37(1), 1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| Chicago | NASERI AMIR,İDER Merve Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. Eurasian Journal of Veterinary Sciences 37, no.1 (2021): 1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| MLA | NASERI AMIR,İDER Merve Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. Eurasian Journal of Veterinary Sciences, vol.37, no.1, 2021, ss.1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| AMA | NASERI A,İDER M Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. Eurasian Journal of Veterinary Sciences. 2021; 37(1): 1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| Vancouver | NASERI A,İDER M Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis. Eurasian Journal of Veterinary Sciences. 2021; 37(1): 1 - 8. 10.15312/EurasianJVetSci.2021.319 |
| IEEE | NASERI A,İDER M "Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis." Eurasian Journal of Veterinary Sciences, 37, ss.1 - 8, 2021. 10.15312/EurasianJVetSci.2021.319 |
| ISNAD | NASERI, AMIR - İDER, Merve. "Comparison of blood gases, hematological and monitorization parameters and determine prognostic importance of selected variables in hypotensive and non-hypotensive calves with sepsis". Eurasian Journal of Veterinary Sciences 37/1 (2021), 1-8. https://doi.org/10.15312/EurasianJVetSci.2021.319 |
