Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender
Yıl: 2021 Cilt: 11 Sayı: 3 Sayfa Aralığı: 277 - 285 Metin Dili: İngilizce DOI: 10.5222/buchd.2021.93709 İndeks Tarihi: 15-02-2022
Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender
Öz: Objective: Corpus Callosum (CC) is a dynamic organ that undergoes morphological modifications throughout life which must be taken into account for appropriate evaluation of CC. The objectives of this study were to provide normative data about the morphological modifications in CC during childhood and to evaluate possible differences related to age and sex. Methods: In this retrospective study, cranial MRI studies of 320 children (160 boys, and 160 girls) between 2 to 17 years old with normal neurologic examination findings were reviewed. We divided the age groups as increments of 1 year, and included 10 girls and 10 boys, in each age group. The following parameters were measured on midsagittal T1-weighted images: area of CC (CCA), supracallosal area (SCA), length of CC (LCC), genu thickness (GT), body thickness (BT), splenium thickness (ST), ratio of genu thickness to splenium thickness (GT/ST) and a novel parameter termed callosal index (CCA/SCA). These parameters were correlated with age and sex. Results: All parameter values increased with age. After age 10, there was no evident age or genderrelated changes between groups, except for the 15-year-old group. When we appraised all age groups, we determined that CCA and SCA were larger in boys but the callosal index did not differ between genders. Conclusion: This is the first study which used the modified callosal index in the pediatric age group. Callosal index gives the opportunity to make brain size corrections according to the individual and allows a more accurate and personal measurement in the follow-up of the same individual. This study offers an objective assessment measure.
Anahtar Kelime: Çocuklarda Korpus Kallozumun Manyetik Rezonans Görüntüleme ile Morfometrik Analizi; Yaş ve Cinsiyetle Korelasyon
Öz: Amaç: Korpus Kallozum (KK), yaşam boyu morfolojik değişiklikler gösteren dinamik bir organdır. Günlük pratikte KK değerlendirmesi subjektif yapılsa da daha doğru değerlendirme yapabilmek yaş ve cinsiyete göre hazırlanmış referans değerlere ihtiyaç vardır. Bu çalışmanın amacı, çocuklarda yaş grubuna göre referans değerleri sağlamanın yanı sıra ve yaş ve cinsiyet farklılıklarını değerlendirmektir. Ek olarak kişinin kendi KK’si ile beyin alanını oranlayarak kişiselleştirilmiş ölçüm yapılmasına imkan veren Modifiye Kallozal İndeksi çocuklarda değerlendirmeyi amaçladık. Yöntem: Retrospektif dizayn edilmiş çalışmamızda, nörolojik muayene bulguları normal olan 2-17 yaş arası 320 çocuğun (160 erkek, 160 kız) kraniyal MRG’leri incelendi. Midsagittal planda T1 görüntülerde: KK alanı (CCA), suprakallozal alan (SCA), KK uzunluğu (LCC), genu kalınlığı (GT), gövde kalınlığı (BT), splenium kalınlığı (ST), genu kalınlığının splenium kalınlığına oranı (GT / ST) ve callosal indeksi (CCA / SCA) olarak adlandırılan yeni bir parametre değerlendirildi. Bu parametrelerin yaş ve cinsiyet ile ilişkisi değerlendirildi. Bulgular: Değerlendirilen tüm parametreler yaşla artış göstermiştir. 10 yaşından sonra 15 yaşındaki grup dışında, gruplar arasında yaş veya cinsiyetle ilgili istatistiksel olarak anlamlı farklılık saptanmadı. Tüm yaş gruplarını değerlendirdiğimizde, erkek çocuklarda CCA ve SCA’nın daha büyük olduğunu ancak kallozal indeksin cinsiyetler arasında istatistiksel olarak anlamlı farklılık göstermediğini belirledik. Sonuç: Çalışmamız, KK değerlendirilirken yaşa ve cinsiyete göre gösterdiği değişikliği göz önünde bulundurarak objektif ölçüme olanak sağlayan bir referans değer belirlemesi açısından önemlidir. Ayrıca kantitatif modifiye kallozal indeksi çocuklarda kullanan ilk çalışmadır
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Arioz Habibi H, Gül O, ÖZTÜRK M, Caliskan E (2021). Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. , 277 - 285. 10.5222/buchd.2021.93709 |
| Chicago | Arioz Habibi Hatice,Gül Ozan Berk,ÖZTÜRK MEHMET,Caliskan Emine Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. (2021): 277 - 285. 10.5222/buchd.2021.93709 |
| MLA | Arioz Habibi Hatice,Gül Ozan Berk,ÖZTÜRK MEHMET,Caliskan Emine Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. , 2021, ss.277 - 285. 10.5222/buchd.2021.93709 |
| AMA | Arioz Habibi H,Gül O,ÖZTÜRK M,Caliskan E Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. . 2021; 277 - 285. 10.5222/buchd.2021.93709 |
| Vancouver | Arioz Habibi H,Gül O,ÖZTÜRK M,Caliskan E Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. . 2021; 277 - 285. 10.5222/buchd.2021.93709 |
| IEEE | Arioz Habibi H,Gül O,ÖZTÜRK M,Caliskan E "Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender." , ss.277 - 285, 2021. 10.5222/buchd.2021.93709 |
| ISNAD | Arioz Habibi, Hatice vd. "Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender". (2021), 277-285. https://doi.org/10.5222/buchd.2021.93709 |
| APA | Arioz Habibi H, Gül O, ÖZTÜRK M, Caliskan E (2021). Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, 11(3), 277 - 285. 10.5222/buchd.2021.93709 |
| Chicago | Arioz Habibi Hatice,Gül Ozan Berk,ÖZTÜRK MEHMET,Caliskan Emine Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi 11, no.3 (2021): 277 - 285. 10.5222/buchd.2021.93709 |
| MLA | Arioz Habibi Hatice,Gül Ozan Berk,ÖZTÜRK MEHMET,Caliskan Emine Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, vol.11, no.3, 2021, ss.277 - 285. 10.5222/buchd.2021.93709 |
| AMA | Arioz Habibi H,Gül O,ÖZTÜRK M,Caliskan E Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi. 2021; 11(3): 277 - 285. 10.5222/buchd.2021.93709 |
| Vancouver | Arioz Habibi H,Gül O,ÖZTÜRK M,Caliskan E Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi. 2021; 11(3): 277 - 285. 10.5222/buchd.2021.93709 |
| IEEE | Arioz Habibi H,Gül O,ÖZTÜRK M,Caliskan E "Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender." İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, 11, ss.277 - 285, 2021. 10.5222/buchd.2021.93709 |
| ISNAD | Arioz Habibi, Hatice vd. "Morphometric Analysis of Corpus Callosum with ID Magnetic Resonance Imaging in Children; Correlation with Age and Gender". İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi 11/3 (2021), 277-285. https://doi.org/10.5222/buchd.2021.93709 |
