Yıl: 2021 Cilt: 11 Sayı: 3 Sayfa Aralığı: 309 - 313 Metin Dili: İngilizce DOI: 10.5222/buchd.2021.93284 İndeks Tarihi: 15-02-2022

Long-Term Follow-up Results of Children Undergoing Achalasia Surgery

Öz:
Objective: Achalasia is a disease characterized by lower esophageal sphincter motility disorder. Whereas there is no clear algorithm in treating achalasia in children, Heller myotomy is known to be as the most effective method. Gastroesophageal reflux after myotomy is a frequently reported complication. Therefore, the fundoplication procedure should be added to the myotomy simultaneously. Our study aimed to present the results of patients who underwent Heller myotomy and fundoplication for achalasia. Materails and Methods: Twelve patients who underwent laparoscopic Heller myotomy with the diagnosis of achalasia between the 2006 and 2019 have been included in the study. Results: There were 12 children. 75% of them were male, and 25% were female. Laparoscopic Heller myotomy and antireflux procedure were applied to all patients. The average nasogastric withdrawal time was 1.75 days, the average time to start feeding was 2.25 days. The average hospital stay was 6.75 days. Dysphagia persisted in 3 patients who underwent Dor fundoplication and in 1 patient who underwent Toupet fundoplication at postoperative 3rd-week controls. It was observed that the symptoms improved after the one-time endoscopic dilatation procedure. Conclusion: Heller myotomy is gold standard method in the treatment of achalasia in children.We believe that partial fundoplication added to myotomy reduces the risk of GER.
Anahtar Kelime:

Akalazya Nedeniyle Ameliyat Edilen Çocukların Uzun Dönem Sonuçları

Öz:
Amaç: Akalazya, alt özofagus sfinkterinde motilite bozukluğuyla karaterize bir hastalıktır. Çocuklarda akalazya tedavisinde net bir algoritma olamamakla birlikte Heller miyotomisi en etkili yöntem olarak kabul edilmektedir. Miyotomi sonrası gastroözofageal reflü sık bildirilen bir komplikasyondur. Bu nedenle miyotomiye eş zamanlı olarak fundoplikasyon prosedürü eklenebilir. Çalışmamızda akalazya nedeniyle Heller myotomi ve fundoplikasyon yapılan hastaların sonuçlarının sunulması amaçlanmıştır. Yöntem: Kliniğimizde 2006-2019 yılları arasında akalazya tanısı ile laparoskopik Heller miyotomisi uygulanan 12 hasta çalışmaya dahil edildi. Bulgular: Olguların %75’i erkek, %25’i kızdı. Hastalara laparoskopik Heller miyotomisi ve antireflü prosedürü uygulandı. Ortalama nazogastrik çekilme süresi 1,75 gün, ortalama beslenmeye başlama zamanı 2,25 gündü. Ortalama hastane yatış süresi 6,75 gündü. Dor fundoplikasyonu uygulanan 3 hastada ve Toupet fundoplikasyonu uygulanan 1 hastada postoperatif 3. hafta kontrollerinde disfajinin devam ettiği görüldü. Tek seferlik endoskopik dilatasyon işlemi sonrası semptomların düzeldiği izlendi. Sonuç: Heller miyotomi çocuklarda akalazya tedavisinde altın standart yöntemdir. Miyotomiye eklenen parsiyel fundoplikasyonun GÖR riskini azalttığını düşünüyoruz.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Bloomston M, Boyce W, Mamel J, Albrink M, Murr M, Durkin A, Rosemurgy A. Videoscopic Heller myotomy for achalasia - Results beyond short-term follow-up. J Surg Res. 2000;92(2):150-6. https://doi.org/10.1006/jsre.2000.5886
  • 2. Lee CW, Kays DW, Chen MK, Islam S. Outcomes of treatment of childhood achalasia. J Pediatr Surg. 2010;332(4):927-32. https://doi.org/10.1016/j.jpedsurg.2010.02.086
  • 3. Franklin AL. Childhood achalasia: A comprehensive review of disease, diagnosis and therapeutic management. World J Gastrointest Endosc. 2014;6(4):105. https://doi.org/10.4253/wjge.v6.i4.105
  • 4. van Lennep M, van Wijk MP, Omari TIM, Benninga MA, Singendonk MMJ. Clinical management of pediatric achalasia. Expert Rev of Gastroenterol and Hepatol. 2018;12(4):391- 404. https://doi.org/10.1080/17474124.2018.1441023. Epub 2018 Feb 26.
  • 5. Meyer A, Catto-Smith A, Crameri J, Simpson D, Alex G, Hardikar W, Cameron D, Oliver M. Achalasia: Outcome in children. J Gastroenterol Hepatol. 2017;32(2):395-400. https://doi.org/10.1111/jgh.13484
  • 6. Litle VR. Laparoscopic Heller Myotomy for Achalasia: A Review of the Controversies. Ann Thorac Surg. 2008;85(2):743-6. https://doi.org/10.1016/j.athoracsur.2007.12.004
  • 7. Nabi Z, Ramchandani M, Chavan R, Darisetty S, Kalapala R, Shava U, Tandan M, Kotla R, Reddy N. Outcome of peroral endoscopic myotomy in children with achalasia. Surg Endosc. 2019;33(11):3656-64. https://doi.org/10.1007/s00464-018-06654-1. Epub 2019 Jan 22.
  • 8. Divarci E. Esophageal Functional Disorders in Children. Turkiye Klin J Pediatr Surg-Special Top. 2015;5(2):47-53. Avaible From: https://www.researchgate.net/ publication/281632867_Cocuklarda_Ozofagus_Fonksiyon_ Bozukluklari
  • 9. Imperiale TF, O’Connor JB, Vaezi MF, Richter JE. A costminimization analysis of alternative treatment strategies for achalasia. Am J Gastroenterol. 2000;95(10):2737-45. https://doi.org/10.1111/j.1572-0241.2000.03181.x
  • 10. Guvenc H, Avtan L, Ekingen G, Sozubir S, Günaltay N, Senel U. Laparoscopic Heller Esophagomyotomy Without Fundoplicatin in Pediatric Achalasia Patients. End Lap ve Minimal İnvaziv Cerrahi Derg. 2002;9(3):171-4. Avaible from: https://www.researchgate.net/ publication/290169161_Laparoscopic_Heller_ esophagomyotomy_in_pediatric_achalasia_disease
  • 11. Di Nardo G, Rossi P, Oliva S, Aloi M, Cozzi D, Frediani S, Redler A, Mallardo S, Ferrari F, Cucchiara S. Pneumatic balloon dilation in pediatric achalasia: Efficacy and factors predicting outcome at a single tertiary pediatric gastroenterology center. Gastrointest Endosc. 2012;76(5):927-32. https://doi.org/10.1016/j.gie.2012.06.035. Epub 2012 Aug 21.
  • 12. Zaheed Hussain S, Thomas R, Tolia V. A review of achalasia in 33 children. Dig Dis Sci. 2002;47(11):2538-43. https://doi.org/10.1023/A:1020572328777
  • 13. Patti MG, Pellegrini CA, Horgan S, Arcerito M, Omelanczuk P, Tamburini A, Diener U, Eubanks TR, Way LW. Minimally invasive surgery for achalasia: An 8-year experience with 168 patients. Ann Surg. 1999;230(4):587-93. https://doi.org/10.1097/00000658-199910000-00014
  • 14. Di Corpo M, Farrell TM, Patti MG. Laparoscopic Heller Myotomy: A Fundoplication Is Necessary to Control Gastroesophageal Reflux. J Laparoendosc Adv Surg Tech. 2019;29(6):721-5. https://doi.org/10.1089/lap.2019.0155. Epub 2019 Apr 19.
  • 15. Diamantis T, Pikoulis E, Felekouras E. Tsigris C, Arvelakis A, Karavokyros I, Bastounis E. Laparoscopic esophagomyotomy for achalasia without a complementary antireflux procedure. J Laparoendosc Adv Surg Tech. 2006;16(4):345-9. https://doi.org/10.1089/lap.2006.16.345
  • 16. Topart P, Deschamps C, Taillefer R, Duranceau A. Long-term effect of total fundoplication on the myotomized esophagus. Ann Thorac Surg. 1992;54(6):1046-51. https://doi.org/10.1016/0003-4975(92)90068-F
  • 17. Rebecchi F, Giaccone C, Farinella E, Campaci R, Morino M. Randomized controlled trial of laparoscopic heller myotomy plus dor fundoplication versus nissen fundoplication for achalasia long-term results. Ann Surg. 2008; 248(6):1023- 30. https://doi.org/10.1097/SLA.0b013e318190a776
APA Bahadır K, ergun e, Jafarov A, Bülbül M, Gollu G, bingöl-koloğlu m, yagmurlu a, cakmak a, Ates U (2021). Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. , 309 - 313. 10.5222/buchd.2021.93284
Chicago Bahadır Kutay,ergun ergun,Jafarov Anar,Bülbül Merve,Gollu Gulnur,bingöl-koloğlu meltem,yagmurlu aydin,cakmak ahmet murat,Ates Ufuk Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. (2021): 309 - 313. 10.5222/buchd.2021.93284
MLA Bahadır Kutay,ergun ergun,Jafarov Anar,Bülbül Merve,Gollu Gulnur,bingöl-koloğlu meltem,yagmurlu aydin,cakmak ahmet murat,Ates Ufuk Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. , 2021, ss.309 - 313. 10.5222/buchd.2021.93284
AMA Bahadır K,ergun e,Jafarov A,Bülbül M,Gollu G,bingöl-koloğlu m,yagmurlu a,cakmak a,Ates U Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. . 2021; 309 - 313. 10.5222/buchd.2021.93284
Vancouver Bahadır K,ergun e,Jafarov A,Bülbül M,Gollu G,bingöl-koloğlu m,yagmurlu a,cakmak a,Ates U Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. . 2021; 309 - 313. 10.5222/buchd.2021.93284
IEEE Bahadır K,ergun e,Jafarov A,Bülbül M,Gollu G,bingöl-koloğlu m,yagmurlu a,cakmak a,Ates U "Long-Term Follow-up Results of Children Undergoing Achalasia Surgery." , ss.309 - 313, 2021. 10.5222/buchd.2021.93284
ISNAD Bahadır, Kutay vd. "Long-Term Follow-up Results of Children Undergoing Achalasia Surgery". (2021), 309-313. https://doi.org/10.5222/buchd.2021.93284
APA Bahadır K, ergun e, Jafarov A, Bülbül M, Gollu G, bingöl-koloğlu m, yagmurlu a, cakmak a, Ates U (2021). Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, 11(3), 309 - 313. 10.5222/buchd.2021.93284
Chicago Bahadır Kutay,ergun ergun,Jafarov Anar,Bülbül Merve,Gollu Gulnur,bingöl-koloğlu meltem,yagmurlu aydin,cakmak ahmet murat,Ates Ufuk Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi 11, no.3 (2021): 309 - 313. 10.5222/buchd.2021.93284
MLA Bahadır Kutay,ergun ergun,Jafarov Anar,Bülbül Merve,Gollu Gulnur,bingöl-koloğlu meltem,yagmurlu aydin,cakmak ahmet murat,Ates Ufuk Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, vol.11, no.3, 2021, ss.309 - 313. 10.5222/buchd.2021.93284
AMA Bahadır K,ergun e,Jafarov A,Bülbül M,Gollu G,bingöl-koloğlu m,yagmurlu a,cakmak a,Ates U Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi. 2021; 11(3): 309 - 313. 10.5222/buchd.2021.93284
Vancouver Bahadır K,ergun e,Jafarov A,Bülbül M,Gollu G,bingöl-koloğlu m,yagmurlu a,cakmak a,Ates U Long-Term Follow-up Results of Children Undergoing Achalasia Surgery. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi. 2021; 11(3): 309 - 313. 10.5222/buchd.2021.93284
IEEE Bahadır K,ergun e,Jafarov A,Bülbül M,Gollu G,bingöl-koloğlu m,yagmurlu a,cakmak a,Ates U "Long-Term Follow-up Results of Children Undergoing Achalasia Surgery." İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, 11, ss.309 - 313, 2021. 10.5222/buchd.2021.93284
ISNAD Bahadır, Kutay vd. "Long-Term Follow-up Results of Children Undergoing Achalasia Surgery". İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi 11/3 (2021), 309-313. https://doi.org/10.5222/buchd.2021.93284