Objective: Coronavirus disease 2019 (COVID-19) has been declared a pandemic by the World Health Organization. Many studies have examined their psychological effects. However, during these periods when the new case of COVID-19 patients decreased, their psychological effects were not sufficiently reported. Our aim was to investigate the anxiety and depressive symptom levels of healthcare workers (HCW) during the periods when the increase in the number of cases slowed down in the COVID-19 epidemic. Materials and Methods: A cross-sectional a questionnaire consisted of Beck Depression Inventory and Beck Anxiety Inventory was applied to 143 people working in a university hospital. General information such as age, gender, marital status, study history in the COVID-19 pandemic, history of chronic disease, and whether there are other HCW at home was collected and compared. Results: The median value of beck anxiety score was 6. The median value of Beck depression score varies by gender (p=0.015). Median value of Beck depression score varies according to marital status (p=0.011). The median value of Beck anxiety score varies according to gender (p=0.008). The median value of Beck anxiety score varies according to occupational groups (p=0.003). A significant link was obtained between Beck depression groups and marital status (p<0.001). Conclusion: COVID-19 shows that it emphasizes ways to reduce mental health risks and adjust interventions under pandemic conditions.