TY  - JOUR
TI  - The use of laboratory parameters and computed tomography score to determine intensive care unit requirement in COVID-19
AB  - Objectives: It is vital to determine the intensive care unit (ICU) requirement at an early stage to reduce the mortality rate in COVID-19 patients. The aim of the study was to find reliable predictive markers to determine the ICU requirement. Methods: We retrospectively reviewed the clinical and laboratory records of 151 COVID-19 patients. The predictive abilities of biochemical parameters and computed tomog raphy (CT) score were evaluated to determine of ICU requirement. Results: The area under curve (AUC) values for procalci tonin, D-Dimer, C reactive protein (CRP), glucose, lactate dehydrogenase (LDH) and CT score were found higher than those for other parameters in the prediction of ICU requi rement. The negative predictive values of these markers were higher than their positive predictive values. CT score was found to be highly correlated with fibrinogen and CRP. The glucose levels [odd ratio (OR): 95% CI; 1.07, p-value: 0.014] and CT score [OR: 95% CI; 1.05, p-value: 0.022] were associated with ICU requirement in COVID-19 patients. Conclusions: CT score, procalcitonin, D-Dimer, CRP, glucose, and LDH are potential predictors to rule out ICU requirement on hospital admission. Fibrinogen and CRP can be used to follow up and predict lung damages in patients with COVID-19.
AU  - hasbek, mürşit
AU  - BOLAT, Serkan
AU  - DOĞAN, Kübra
AU  - ÇAYLAK, HALİL
AU  - DOĞAN, Halef Okan
AU  - ÇETİNKAYA, NAZIM
AU  - Sarıismailoğlu, Rağıp
AU  - BÜYÜKTUNA, Seyit Ali
DO  - 10.1515/tjb-2020-0359
PY  - 2021
JO  - Türk Biyokimya Dergisi
VL  - 46
IS  - 2
SN  - 1303-829X
SP  - 157
EP  - 166
DB  - TRDizin
UR  - http://search/yayin/detay/492678
ER  -