Yıl: 2021 Cilt: 9 Sayı: 4 Sayfa Aralığı: 490 - 497 Metin Dili: İngilizce DOI: 10.14235/bas.galenos.2021.5375 İndeks Tarihi: 23-02-2022

Probiotics and Relationship Between Probiotics and Cancer Types

Öz:
Cancer is a disease with a high mortality rate worldwide. Moreover, this rate is increasing day by day. It is expected to rise to first place by 2030, leaving cardiovascular diseases behind, which is the most common cause of death in the world. Today, it is known that cancer is the second most common cause of death. The process of cancer and its treatment reducethe quality of life. To improve this process, the effects of probiotics on some types of cancer, especially colorectal cancer, are examined in studies conducted today. Studies are showing that probiotics provide positive results in cancer prevention and treatment. However, some studies argue that they should not be used, putting forward the fact they may cause infection in patients with very weak immunity. The mechanisms for the antitumor properties of probiotics have not been fully explained yet. It is associated with some pathways which mainly focus on the gut microbiota. The opinion that the effects of probiotics on cancer are dependent on dose, strain, and species is accepted as a general conclusion. Besides, probiotics must be consumed regularly and the consumed product must contain the minimum number of microorganisms (approximately 100 g/day) to provide the intended effect. In this review, the effects of probiotics, of which positive and negative effects on individuals with cancer are still being discussed, on different types of cancer are presented in the light of current literature.
Anahtar Kelime:

Probiyotikler ve Probiyotiklerin Kanser Türleriyle İlişkisi

Öz:
Kanser, dünya genelinde ölüm oranı oldukça yüksek olan bir hastalıktır. Üstelik bu oran her geçen gün yükselmektedir. Öyle ki, 2030 yılına kadar dünyada görülen en yaygın ölüm nedeni olan kardiyovasküler hastalıkları geride bırakarak birinci sıraya yükselmesi beklenmektedir. Günümüzde kanserin ikinci en yaygın ölüm nedeni olduğu bilinmektedir. Kanser süreci ve tedavisi hayat kalitesini düşürmektedir. Bu süreci iyileştirmek adına, günümüzde yapılan çalışmalarda, kolorektal kanser başta olmak üzere bazı kanser türlerinde probiyotiklerin etkisi incelenmektedir. Probiyotiklerin kanseri önlemede ve kanser tedavisinde olumlu sonuçlar verdiğine dair çalışmalar bulunmaktadır. Ancak, bağışıklığı çok zayıf olan hastalarda infeksiyona neden olabileceği gibi sebepler öne sürülerek kullanılmaması gerektiğini savunan çalışmalar da mevcuttur. Probiyotiklerin antitümör özelliklerine dair mekanizmalar, henüz tam anlamıyla açıklanamamıştır. Merkezinde barsak mikrobiyotasının bulunduğu bazı yolaklarla ilişkilendirilmektedir. Probiyotiklerin kanser üzerine olan etkilerinin doza, suşa ve türe bağlı olduğu görüşü, genel bir sonuç olarak kabul edilmektedir. Ayrıca, probiyotiklerin istenilen etkiyi sağlayabilmeleri için düzenli bir şekilde tüketilmesi ve tüketilen ürünün minimum mikroorganizma sayısını (yaklaşık olarak 100 g/gün) içermesi gerekmektedir. Bu derlemede, kanserli bireyler üzerindeki olumlu ve olumsuz etkileri hala tartışılmakta olan probiyotiklerin farklı kanser türleri üzerine etkileri güncel literatür ışığında sunulmaktır.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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APA Şener D, BULUT H, GÜNEŞ BAYIR A (2021). Probiotics and Relationship Between Probiotics and Cancer Types. , 490 - 497. 10.14235/bas.galenos.2021.5375
Chicago Şener Dilruba,BULUT Hafsa Nur,GÜNEŞ BAYIR AYŞE Probiotics and Relationship Between Probiotics and Cancer Types. (2021): 490 - 497. 10.14235/bas.galenos.2021.5375
MLA Şener Dilruba,BULUT Hafsa Nur,GÜNEŞ BAYIR AYŞE Probiotics and Relationship Between Probiotics and Cancer Types. , 2021, ss.490 - 497. 10.14235/bas.galenos.2021.5375
AMA Şener D,BULUT H,GÜNEŞ BAYIR A Probiotics and Relationship Between Probiotics and Cancer Types. . 2021; 490 - 497. 10.14235/bas.galenos.2021.5375
Vancouver Şener D,BULUT H,GÜNEŞ BAYIR A Probiotics and Relationship Between Probiotics and Cancer Types. . 2021; 490 - 497. 10.14235/bas.galenos.2021.5375
IEEE Şener D,BULUT H,GÜNEŞ BAYIR A "Probiotics and Relationship Between Probiotics and Cancer Types." , ss.490 - 497, 2021. 10.14235/bas.galenos.2021.5375
ISNAD Şener, Dilruba vd. "Probiotics and Relationship Between Probiotics and Cancer Types". (2021), 490-497. https://doi.org/10.14235/bas.galenos.2021.5375
APA Şener D, BULUT H, GÜNEŞ BAYIR A (2021). Probiotics and Relationship Between Probiotics and Cancer Types. Bezmiâlem Science, 9(4), 490 - 497. 10.14235/bas.galenos.2021.5375
Chicago Şener Dilruba,BULUT Hafsa Nur,GÜNEŞ BAYIR AYŞE Probiotics and Relationship Between Probiotics and Cancer Types. Bezmiâlem Science 9, no.4 (2021): 490 - 497. 10.14235/bas.galenos.2021.5375
MLA Şener Dilruba,BULUT Hafsa Nur,GÜNEŞ BAYIR AYŞE Probiotics and Relationship Between Probiotics and Cancer Types. Bezmiâlem Science, vol.9, no.4, 2021, ss.490 - 497. 10.14235/bas.galenos.2021.5375
AMA Şener D,BULUT H,GÜNEŞ BAYIR A Probiotics and Relationship Between Probiotics and Cancer Types. Bezmiâlem Science. 2021; 9(4): 490 - 497. 10.14235/bas.galenos.2021.5375
Vancouver Şener D,BULUT H,GÜNEŞ BAYIR A Probiotics and Relationship Between Probiotics and Cancer Types. Bezmiâlem Science. 2021; 9(4): 490 - 497. 10.14235/bas.galenos.2021.5375
IEEE Şener D,BULUT H,GÜNEŞ BAYIR A "Probiotics and Relationship Between Probiotics and Cancer Types." Bezmiâlem Science, 9, ss.490 - 497, 2021. 10.14235/bas.galenos.2021.5375
ISNAD Şener, Dilruba vd. "Probiotics and Relationship Between Probiotics and Cancer Types". Bezmiâlem Science 9/4 (2021), 490-497. https://doi.org/10.14235/bas.galenos.2021.5375