Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives

Duygu BAYRAMOĞLU, (Ankara Üniversitesi, Fen Fakültesi, Kimya Bölümü, Ankara, Türkiye)
Mehtap YAKUT (Ankara Üniversitesi, Fen Fakültesi, Kimya Bölümü, Ankara, Türkiye)
Düzce Üniversitesi Bilim ve Teknoloji Dergisi
11 2
Yıl: 2021 Cilt: 9 Sayı: 5 Sayfa Aralığı: 1610 - 1620 Metin Dili: İngilizce DOI: 10.29130/dubited.926881 İndeks Tarihi: 31-03-2022

Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives

Öz:
An efficient green approach for the synthesis of 9-heteroaryl-acridine-1,8-dione derivatives (3a-f) was accomplished via reactions of dimedone (1) with various heteroaromatic aldehydes (2a-f) and ammonium acetate through one-pot multicomponent reactions in water under mild conditions using ultrasound irradiation in excellent yields. Of the synthesized compounds, 3d-f were novel and this process presents the advantages of high yields and easy work-up procedures. Spectral analyses were accomplished by FTIR, 1H NMR, 13C NMR and LC-MS TOF analyses.
Anahtar Kelime:

Ultrases Destekli 9-(Substitue heteroaril) akridindion Türevlerinin Tek Basamakta Sentezi

Öz:
Bu çalışma ile 9-heteroaril akridin-1,8-dion türevlerinin (3a-f) sentezi için yeşil kimya yaklaşımını benimseyen etkili bir yöntem geliştirilmiştir. Dimedon’un (1), çeşitli heteroaromatik aldehitlerle (2a-f) amonyum asetat kullanılarak sulu ortamda ve tek kapta ultrases dalgaları ile reaksiyonları gerçekleştirilmiştir. Bu yöntem ile ılıman koşullar altında, hedeflenen moleküller yüksek verimle elde edilmiştir. Ayrıca yöntemin kolay uygulanabilir olması ve deney sonrası işlemlerinin son derece basit olması en önemli çalışma avantajlarındandır. Sentezlenen bileşiklerden 3d-f orijinal moleküller olup, elde edilen tüm ürünlerin karakterizasyonları FTIR, 1H NMR, 13C NMR ve LC-MS TOF analizleri kullanılarak gerçekleştirilmiştir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA bayramoğlu d, Özgür (nee Yakut) M (2021). Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . , 1610 - 1620. 10.29130/dubited.926881
Chicago bayramoğlu duygu,Özgür (nee Yakut) Mehtap Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . (2021): 1610 - 1620. 10.29130/dubited.926881
MLA bayramoğlu duygu,Özgür (nee Yakut) Mehtap Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . , 2021, ss.1610 - 1620. 10.29130/dubited.926881
AMA bayramoğlu d,Özgür (nee Yakut) M Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . . 2021; 1610 - 1620. 10.29130/dubited.926881
Vancouver bayramoğlu d,Özgür (nee Yakut) M Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . . 2021; 1610 - 1620. 10.29130/dubited.926881
IEEE bayramoğlu d,Özgür (nee Yakut) M "Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives ." , ss.1610 - 1620, 2021. 10.29130/dubited.926881
ISNAD bayramoğlu, duygu - Özgür (nee Yakut), Mehtap. "Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives ". (2021), 1610-1620. https://doi.org/10.29130/dubited.926881
APA bayramoğlu d, Özgür (nee Yakut) M (2021). Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 9(5), 1610 - 1620. 10.29130/dubited.926881
Chicago bayramoğlu duygu,Özgür (nee Yakut) Mehtap Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . Düzce Üniversitesi Bilim ve Teknoloji Dergisi 9, no.5 (2021): 1610 - 1620. 10.29130/dubited.926881
MLA bayramoğlu duygu,Özgür (nee Yakut) Mehtap Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . Düzce Üniversitesi Bilim ve Teknoloji Dergisi, vol.9, no.5, 2021, ss.1610 - 1620. 10.29130/dubited.926881
AMA bayramoğlu d,Özgür (nee Yakut) M Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . Düzce Üniversitesi Bilim ve Teknoloji Dergisi. 2021; 9(5): 1610 - 1620. 10.29130/dubited.926881
Vancouver bayramoğlu d,Özgür (nee Yakut) M Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives . Düzce Üniversitesi Bilim ve Teknoloji Dergisi. 2021; 9(5): 1610 - 1620. 10.29130/dubited.926881
IEEE bayramoğlu d,Özgür (nee Yakut) M "Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives ." Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 9, ss.1610 - 1620, 2021. 10.29130/dubited.926881
ISNAD bayramoğlu, duygu - Özgür (nee Yakut), Mehtap. "Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives ". Düzce Üniversitesi Bilim ve Teknoloji Dergisi 9/5 (2021), 1610-1620. https://doi.org/10.29130/dubited.926881
Sayfa Oluşturulma Tarihi
24-04-2024 22:42

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