TY  - JOUR
TI  - Diversity of Lactococcus garvieae by Genomic Approaches
AB  - Lactococcus garvieae is the Gram-positive cocci bacteria known as the causative agent of infectious systemic disease. It causes fatal hemorrhagic septicemia in mainly cultured fish species, animals, and humans worldwide. Comparative genome analyses provide valuable information about genome identification and unique genomic features. In this study, the available L. garvieae genomes are evaluated by comparative genomics approaches. The results indicated that there are four distinct genetic groups of L. garvieae based on the Average Nucleotide Identity (ANI) value. The phylogenetic tree was produced using 16S rRNA sequence has similar genetic variances with the publicly available L. garvieae genome data on NCBI and supports the ANI value. In silico analysis of antimicrobial resistance revealed that each L. garvieae genome groups have unique antimicrobial resistance class genes, even though, all genomes have a common antibiotic-resistant class. Analyzing results of the antimicrobial resistance supports the L. garvieae genetic variations. This extensively comparative approach will provide new insights into the understanding of L. garvieae genomic diversity and antimicrobial resistance.
AU  - Kumru, Salih
DO  - 10.35229/jaes.894280
PY  - 2021
JO  - JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES
VL  - 6
IS  - 4
SN  - 2548-0006
SP  - 506
EP  - 513
DB  - TRDizin
UR  - http://search/yayin/detay/502758
ER  -