Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi

Didem PEKMEZCİ, (Ondokuz Mayıs Üniversitesi, Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı, Samsun, Türkiye)
Zeynep Nurselin COLAK (Ondokuz Mayıs Üniversitesi, Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı, Samsun, Türkiye)
JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES
18 0
Yıl: 2021 Cilt: 6 Sayı: 4 Sayfa Aralığı: 585 - 591 Metin Dili: Türkçe DOI: 10.35229/jaes.993377 İndeks Tarihi: 29-07-2022

Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi

Öz:
Nötrofil/lenfosit oranı (NEU/LYM), monosit/lenfosit oranı (MONO/LYM), ve platelet/lenfosit oranı (PLT/LYM) inflamasyonun ucuz, tekrar kullanılabilen biyobelirteçlerini oluşturmaktadır. Bu çalışma ilk defa parvovirus enfeksiyonu (PVE) şekillenmiş köpeklerde NEU/LYM, MONO/LYM ve PLT/LYM değerlerini ortaya koymaktadır. Çalışmanın amacını ise tedavi öncesi PVE ile pozitif köpeklerin NEU/LYM, MONO/LYM ve PLT/LYM değerlerinin, sağlıklı kontrollere göre karşılaştırılması oluşturmuştur. On sekiz sahipli, 2-6 aylık, PVE pozitif köpek, çalışma grubunu oluşturmuştur. Yedi sahipli, 8-10 aylık yaş aralığında sağlıklı köpek ise kontrol grubunu oluşturmuştur. Gruplar arasında tedavi öncesi NEU/LYM, MONO/LYM karşılaştırılmasında PVE pozitif grubu NEU (P<0,001), LYM (P<0,05) değerleri kontrol grubuna göre istatistiksel olarak düşük bulunmuştur. Bununla birlikte, PVE pozitif grubunda tedavi öncesi PLT/LYM seviyeleri kontrol grubuna göre istatistiksel olarak yüksek (P<0,001) tespit edilmiştir. PVE pozitif ve kontrol gruplarında PLT/LYM düzeyleri ise sırasıyla 1120,94 ve 135,26 olarak bulunmuştur. Sonuç olarak, bu ön çalışma PLT/LYM oranın, PVE ile doğal olarak enfekte köpeklerde kolay, uygun maliyetli, objektif ve invazif olmayan yeni bir prognostik belirteç adayı olabileceğini göstermektedir. NEU/LYM, MONO/LYM, PLT/LYM ile ilgili çalışmaların kısıtlı varlığına rağmen, özellikle veteriner hekimlikte enfeksiyöz hastalıklarda daha ileri çalışmalara ihtiyaç duyulmaktadır.
Anahtar Kelime: Nötrofil/lenfosit oranı Köpek Platelet/lenfosit oranı Parvovirus Monosit/lenfosit oranı

Determination of Neutrophil/Lymphocyte, Monocyte/Lymphocyte and Platelet/Lymphocyte Ratios in Dogs with Occurring Parvovirus Infection

Öz:
Neutrophil/lymphocyte ratio (NEU/LYM), monocyte/lymphocyte ratio (MONO/LYM), and platelet/lymphocyte ratio (PLT/LYM) are inexpensive and reproducible biomarkers of inflammation. This is the first study that explores NEU/LYM, MONO/LYM, and PLT/LYM in dogs with Parvovirus infection (PVI). This study aims to determine whether the pretreatment NEU/LYM, MONO/LYM, and PLT/LYM differs in dogs with PVI against healthy controls. Eighteen client-owned dogs aged 2-6 months that were found positive with PVI were enrolled as the study group. Seven client-owned, healthy dogs of the 8-10 months formed the control group. Pretreatment NEU/LYM, MONO/LYM, and PLT/LYM were compared between groups. The pretreatment NEU (P< 0.001) and LYM (P<0.05) levels were found to be significantly lower in the study group when compared to the control group. However, pretreatment PLT/LYM levels in the PVI positive group was significantly higher (P<0.001) than in the control group. PLT/LYM levels in the PVI and control groups were found as 1120.94 and 135.26, respectively. In summary, this preliminary study demonstrates that pretreatment PLT/LYM in dogs with PVI is an easy, cost-effective, objective, and non-invasive biomarker that could be the new prognostic marker candidates in dogs naturally infected with PVI. Although limited studies on NEU/LYM, MONO/LYM, PLT/LYM are existed, especially further studies in veterinary medicine with infectious diseases are needed.
Anahtar Kelime: Parvovirus

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA PEKMEZCİ D, KOT Z (2021). Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. , 585 - 591. 10.35229/jaes.993377
Chicago PEKMEZCİ Didem,KOT ZEYNEP NURSELİN Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. (2021): 585 - 591. 10.35229/jaes.993377
MLA PEKMEZCİ Didem,KOT ZEYNEP NURSELİN Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. , 2021, ss.585 - 591. 10.35229/jaes.993377
AMA PEKMEZCİ D,KOT Z Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. . 2021; 585 - 591. 10.35229/jaes.993377
Vancouver PEKMEZCİ D,KOT Z Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. . 2021; 585 - 591. 10.35229/jaes.993377
IEEE PEKMEZCİ D,KOT Z "Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi." , ss.585 - 591, 2021. 10.35229/jaes.993377
ISNAD PEKMEZCİ, Didem - KOT, ZEYNEP NURSELİN. "Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi". (2021), 585-591. https://doi.org/10.35229/jaes.993377
APA PEKMEZCİ D, KOT Z (2021). Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES, 6(4), 585 - 591. 10.35229/jaes.993377
Chicago PEKMEZCİ Didem,KOT ZEYNEP NURSELİN Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES 6, no.4 (2021): 585 - 591. 10.35229/jaes.993377
MLA PEKMEZCİ Didem,KOT ZEYNEP NURSELİN Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES, vol.6, no.4, 2021, ss.585 - 591. 10.35229/jaes.993377
AMA PEKMEZCİ D,KOT Z Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES. 2021; 6(4): 585 - 591. 10.35229/jaes.993377
Vancouver PEKMEZCİ D,KOT Z Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi. JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES. 2021; 6(4): 585 - 591. 10.35229/jaes.993377
IEEE PEKMEZCİ D,KOT Z "Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi." JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES, 6, ss.585 - 591, 2021. 10.35229/jaes.993377
ISNAD PEKMEZCİ, Didem - KOT, ZEYNEP NURSELİN. "Parvovirus ile Enfekte Köpeklerde Nötrofil/Lenfosit, Monosit/Lenfosit ve Platelet/Lenfosit Oranlarının Belirlenmesi". JOURNAL OF ANATOLIAN ENVIRONMENTAL AND ANIMAL SCIENCES 6/4 (2021), 585-591. https://doi.org/10.35229/jaes.993377
Sayfa Oluşturulma Tarihi
23-04-2024 22:5

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