TY  - JOUR
TI  - Is there any contribution of bronchial washing to biopsy in the diagnosis of patients with endobronchial pathology in the era of personalized medicine?
AB  - Introduction: Bronchoscopic biopsies and bronchial washings (BW) are commonly used together for the diagnosis of centrally located tumors. This study aimed to investigate the clinical relevance of routinely collecting BWs in patients who simultaneously had biopsies for visible endobronchial lesions in the current molecular analysis-driven personalized medicine era. Materials and Methods: We retrospectively reviewed the patients who underwent fiberoptic bronchoscopy (FOB) between October 2011 and December 2016. Patients who had both BW and biopsy specimens (EBB: endobronchial forceps biopsy and/or EBNA: endobronchial needle aspiration biopsy) for visible endobronchial lesions were included in this study. Demographic and clinical data, macroscopic findings during FOB, pathology results, and final diagnoses were collected from the hospital database. Results: The study included 269 patients (220 males/49 females) with a mean age of 61.6 ± 10.6 years. While the overall diagnostic yield of FOB was 71.4%, the diagnostic yields of bronchoscopic procedures were 68.2% for EBB, 83.3% for EBNA, and 19.7% for BW. Only three patients (1.1%) with undiagnostic biopsies had positive BW cytology revealing merely malignant epithelial cells. Conclusion: BW provided a negligible diagnostic contribution in 1.1% (n= 3) of the patients. These three patients had undergone further diagnostic procedures for making a proper therapeutic management plan. In the era of personalized therapy, it is logical to obtain more biopsy in the time spent for BWs.
AU  - karcıoğlu, oğuz
AU  - ONDER, SEVGEN ÇELIK
AU  - SARINC ULASLI, SEVINC
AU  - Sertçelik, Ümran
AU  - Keles, Emine
AU  - babaoglu, elif
AU  - Koksal, Deniz
DO  - 10.5578/tt.20219702
PY  - 2021
JO  - Tüberküloz ve Toraks
VL  - 69
IS  - 3
SN  - 0494-1373
SP  - 307
EP  - 313
DB  - TRDizin
UR  - http://search/yayin/detay/503990
ER  -