Hypocalcemia is a common and significant complication that may develop after a total thyroidectomy operation. In our study, the effects of neuromonitoring on the development of hypocalcemia in total thyroidectomy operations were retrospectively investigated. Patients who underwent only total thyroidectomy in our clinic between 2013 and 2020 and had no history of operation or radiation treatment in their neck region were retrospectively evaluated and divided into two groups. A total of 96 patients, 42 patients in Group 1 on whom neuromonitoring was used and 54 patients in Group 2 without neuromonitoring, were examined. Transient hypocalcemia was manifest in 12 (28.5%) of the 42 patients in Group 1 and 16 (29.6%) of the 54 patients in Group 2, while the difference between the two groups was not statistically significant (p=0.910). In total thyroidectomy operations, the proven benefits of using intraoperative neuromonitoring are still controversial. In our study, it was observed that intraoperative neuromonitoring did not make a significant difference in transient hypocalcemia development after total thyroidectomy operations.