TY - JOUR TI - Experience of ibrutinib in a patient with recurrent mantle cell lymphoma with orbital involvement AB - Mantle cell lymphoma is a subtype of B cell non-Hodgkin's lymphoma with different clinical and molecular features. Extranodal involvement is common in MCL. Bone marrow, liver, spleen, waldeyer ring and gastrointestinal involvement are most common. Lymphomatosis polyposis can be seen in some patients. Central nervous system involvement is rare. Here, we aimed to present a blastoid variant MCL patient who developed orbital recurrence after four lines of systemic therapy and responded to ibrutinib (560 mg/day) monotherapy. The mass disappeared completely in the bilateral orbital MRI taken after the 5th month of the ibrutinib treatment. AU - ERKURT, MEHMET ALI AU - BERBER, Ilhami AU - SARICI, AHMET AU - Biçim, Soykan AU - KUKU, IRFAN AU - BAHÇECİOĞLU, ÖMER FARUK AU - ER ULUBABA, HİLAL AU - Kaya, Emin DO - 10.5455/medscience.2021.04.139 PY - 2021 JO - Medicine Science VL - 10 IS - 4 SN - 2147-0634 SP - 1542 EP - 1545 DB - TRDizin UR - http://search/yayin/detay/504869 ER -