Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature

SERRANO, ALVARO; Jerónimo, Barrera; Valladares Diez, Luis; CORTÉS TORO, JOSÉ ANTONIO; Gonzalez-Peramato Gutierrez, Maria Del Pilar; MORENO, Jes s; HERMİDA, Juan; de la Parra, Irene; Gómez Moreno, Angel; Vives, Roser

Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature

Irene De La Parra, (Department of Urology, Health Research Institute, Clínico San Carlos Hospital, Complutense University, Madrid, Spain)

lvaro SERRANO, (Department of Urology, Health Research Institute, Clínico San Carlos Hospital, Complutense University, Madrid, Spain)

Roser Vives, (Department of Urology, Health Research Institute, Clínico San Carlos Hospital, Complutense University, Madrid, Spain)

Juan Hermida, (Department of Urology, Health Research Institute, Clínico San Carlos Hospital, Complutense University, Madrid, Spain)

Luis Ignacio Diez-Valladares, (Department of General Surgery, Clínico San Carlos Hospital, Madrid, Spain)

Jer nimo BARRERA, (Department of Radiology, Clínico San Carlos Hospital, Madrid, Spain)

Jos Antonio CORT S, (Department of Pathology, Clínico San Carlos Hospital, Madrid, Spain)

Pilar GONZ LEZ-PERAMATO, (Department of Pathology, University Hospital La Paz, Autónoma University, Madrid, Spain)

ngel G MEZ, (Department of Urology, Health Research Institute, Clínico San Carlos Hospital, Complutense University, Madrid, Spain)

Jes s MORENO (Department of Urology, Health Research Institute, Clínico San Carlos Hospital, Complutense University, Madrid, Spain)

Eurasian Journal of Medicine and Oncology

8 2

Yıl: 2021 Cilt: 5 Sayı: 4 Sayfa Aralığı: 361 - 367 Metin Dili: İngilizce İndeks Tarihi: 17-05-2022

Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature

Öz:

Chromophobe renal cell carcinoma (ChRCC) accounts for 4-6% of RCC1. Most of ChRCC have good prognosis, but sarcomatoid transformation implies poor prognosis factor2. Although sarcomatoid RCC was initially described as an own histological entity3, despite the fact that its transformation mechanism is not known, it is nowadays recognized that this histology represents a transformation or dedifferentiation of a high-grade malignant neoplasia originating from any other histological subtype of RCC2. ChRCC with sarcomatoid differentiation is very rare, with a few reported cases and there is no consensus about the treatment of patients affected by this variant of RCC in the guidelines. Therefore, we consider appropriate to present these two cases and review the literature, focusing on the incidence and the current therapeutic options.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	de la Parra I, SERRANO A, Vives R, HERMİDA J, Valladares Diez L, Jerónimo B, CORTÉS TORO J, Gonzalez-Peramato Gutierrez M, Gómez Moreno A, MORENO J (2021). Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. , 361 - 367.
Chicago	de la Parra Irene,SERRANO ALVARO,Vives Roser,HERMİDA Juan,Valladares Diez Luis,Jerónimo Barrera,CORTÉS TORO JOSÉ ANTONIO,Gonzalez-Peramato Gutierrez Maria Del Pilar,Gómez Moreno Angel,MORENO Jes s Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. (2021): 361 - 367.
MLA	de la Parra Irene,SERRANO ALVARO,Vives Roser,HERMİDA Juan,Valladares Diez Luis,Jerónimo Barrera,CORTÉS TORO JOSÉ ANTONIO,Gonzalez-Peramato Gutierrez Maria Del Pilar,Gómez Moreno Angel,MORENO Jes s Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. , 2021, ss.361 - 367.
AMA	de la Parra I,SERRANO A,Vives R,HERMİDA J,Valladares Diez L,Jerónimo B,CORTÉS TORO J,Gonzalez-Peramato Gutierrez M,Gómez Moreno A,MORENO J Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. . 2021; 361 - 367.
Vancouver	de la Parra I,SERRANO A,Vives R,HERMİDA J,Valladares Diez L,Jerónimo B,CORTÉS TORO J,Gonzalez-Peramato Gutierrez M,Gómez Moreno A,MORENO J Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. . 2021; 361 - 367.
IEEE	de la Parra I,SERRANO A,Vives R,HERMİDA J,Valladares Diez L,Jerónimo B,CORTÉS TORO J,Gonzalez-Peramato Gutierrez M,Gómez Moreno A,MORENO J "Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature." , ss.361 - 367, 2021.
ISNAD	de la Parra, Irene vd. "Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature". (2021), 361-367.

APA	de la Parra I, SERRANO A, Vives R, HERMİDA J, Valladares Diez L, Jerónimo B, CORTÉS TORO J, Gonzalez-Peramato Gutierrez M, Gómez Moreno A, MORENO J (2021). Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. Eurasian Journal of Medicine and Oncology, 5(4), 361 - 367.
Chicago	de la Parra Irene,SERRANO ALVARO,Vives Roser,HERMİDA Juan,Valladares Diez Luis,Jerónimo Barrera,CORTÉS TORO JOSÉ ANTONIO,Gonzalez-Peramato Gutierrez Maria Del Pilar,Gómez Moreno Angel,MORENO Jes s Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. Eurasian Journal of Medicine and Oncology 5, no.4 (2021): 361 - 367.
MLA	de la Parra Irene,SERRANO ALVARO,Vives Roser,HERMİDA Juan,Valladares Diez Luis,Jerónimo Barrera,CORTÉS TORO JOSÉ ANTONIO,Gonzalez-Peramato Gutierrez Maria Del Pilar,Gómez Moreno Angel,MORENO Jes s Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. Eurasian Journal of Medicine and Oncology, vol.5, no.4, 2021, ss.361 - 367.
AMA	de la Parra I,SERRANO A,Vives R,HERMİDA J,Valladares Diez L,Jerónimo B,CORTÉS TORO J,Gonzalez-Peramato Gutierrez M,Gómez Moreno A,MORENO J Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. Eurasian Journal of Medicine and Oncology. 2021; 5(4): 361 - 367.
Vancouver	de la Parra I,SERRANO A,Vives R,HERMİDA J,Valladares Diez L,Jerónimo B,CORTÉS TORO J,Gonzalez-Peramato Gutierrez M,Gómez Moreno A,MORENO J Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature. Eurasian Journal of Medicine and Oncology. 2021; 5(4): 361 - 367.
IEEE	de la Parra I,SERRANO A,Vives R,HERMİDA J,Valladares Diez L,Jerónimo B,CORTÉS TORO J,Gonzalez-Peramato Gutierrez M,Gómez Moreno A,MORENO J "Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature." Eurasian Journal of Medicine and Oncology, 5, ss.361 - 367, 2021.
ISNAD	de la Parra, Irene vd. "Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature". Eurasian Journal of Medicine and Oncology 5/4 (2021), 361-367.