TY  - JOUR
TI  - Sarcomatoid Transformation of Cromophobe Renal Cell Carcinoma: An Unusual Pathology. Our Experience, Definition of Therapeutic Guidelines and Review of Literature
AB  - Chromophobe renal cell carcinoma (ChRCC) accounts for 4-6% of RCC1. Most of ChRCC have good prognosis, but sarcomatoid transformation implies poor prognosis factor2. Although sarcomatoid RCC was initially described as an own histological entity3, despite the fact that its transformation mechanism is not known, it is nowadays recognized that this histology represents a transformation or dedifferentiation of a high-grade malignant neoplasia originating from any other histological subtype of RCC2. ChRCC with sarcomatoid differentiation is very rare, with a few reported cases and there is no consensus about the treatment of patients affected by this variant of RCC in the guidelines. Therefore, we consider appropriate to present these two cases and review the literature, focusing on the incidence and the current therapeutic options.
AU  - SERRANO, ALVARO
AU  - Jerónimo, Barrera
AU  - Valladares Diez, Luis
AU  - CORTÉS TORO, JOSÉ ANTONIO
AU  - Gonzalez-Peramato Gutierrez, Maria Del Pilar
AU  - MORENO, Jes s
AU  - HERMİDA, Juan
AU  - de la Parra, Irene
AU  - Gómez Moreno, Angel
AU  - Vives, Roser
PY  - 2021
JO  - Eurasian Journal of Medicine and Oncology
VL  - 5
IS  - 4
SN  - 2587-2400
SP  - 361
EP  - 367
DB  - TRDizin
UR  - http://search/yayin/detay/505242
ER  -