Objective: The aim of this study was to examine the relationship between depressive symptoms and physical activity level in Parkinson's disease. Methods: A total of 69 patients, including 25 females (36.2%) and 44 males (63.8%), aged between 58-89 years were included in this prospective study. The Hamilton Depression Rating Scale was used to determine the severity of depressive symptoms, and the International Physical Activity Questionnaire (Short form) was used to determine the physical activity level in patients with Parkinson's disease. Results: While a moderate negative significant correlation was observed between the International Physical Activity Questionnaire and Hamilton Depression Rating Scale in all patients and males, there was no statistically significant correlation in females. A moderate negative significant correlation was observed between age and the International Physical Activity Questionnaire in all patients, females and males. While a moderate positive significant correlation was found between the hamilton depression rating scale and age in all patients and females, a highly positive significant correlation was found in males. Whereas a moderate positive significant correlation was observed between body mass ındex and the hamilton depression rating scale in all patients and females, a weak positive correlation was observed in males. Conclusion: İt was found that the level of depression decreased as the level of physical activity increased in patients with Parkinson's disease. It was observed that physical activity decreased and the level of depressive symptoms increased as the age increased. Furthermore, it was observed that the level of depressive symptoms increased among those with a high body mass ındex. we think that the application of changes in body mass ındex and physical activity level together with the treatments for depressive symptoms will provide positive outcomes.