Yıl: 2005 Cilt: 12 Sayı: 2 Sayfa Aralığı: 133 - 138 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Metabolik sendrom: Önemi ve tedavisi

Öz:
Her biri koroner kalp hastalığı (KKH) riskini artıran abdominal obezite, aterojenik dislipidemi, artmış kan basıncı ve insülin direncinden meydana gelen metabolik sendrom (MS), tüm dünyada giderek artan bir halk sağlığı sorunudur. NCEP kılavuzunun ATP III revizyonuna uygun bir şekilde beş unsurdan üçünün varlığı ile tanı konan MS, toplumumuzda 30 yaş üzerindeki erkek bireylerin %31'inde ve kadın bireylerin %43'ünde olmak üzere toplam 9.2 milyon erişkinimizde mevcuttur. Her 8 erişkinimizin 3'ünde MS var olup, her 6 erişkinimizin 1'i KKH için yüksek riske sahiptir. TEKHARF çalışması veritabanına göre KKH gelişiminin %53'ünden sorumlu tutulan MS, Türk toplumu için de oldukça önemli bir problemdir. Bu derlemede MS fizyopatolojisine kısaca değinilmiş, MS unsurlarının ve tedavi seçeneklerinin koroner kalp hastalığına olan etkileri klinik çalışmalar ışığında gözden geçirilmiştir.
Anahtar Kelime: Metabolik sendrom X Koroner hastalık

Konular: Endokrinoloji ve Metabolizma Kalp ve Kalp Damar Sistemi

Metabolic syndrome: Importance and treatment

Öz:
Metabolic syndrome (MS) is a public health problem which is becoming increasingly common worldwide. Factors characteristic of the MS are abdominal obesity, atherogenic dyslipidemia, high blood pressure and insulin resistance. Each factor is associated with increased risk for coronary heart disease (CHD). MS was defined in conformity with that proposed in the NCEP ATP III guidelines, namely in the presence of 3 out of 5 relevant components. This syndrome was identified in Turkish population in 31% of men and 43% of women with a total of 9.2 million adults. MS existed in 3 out of each 8 adults and 1 out of 6 adults have high risk for CHD. According to TEKHARF study, metabolic syndrome was present in 53% of patients with established CHD so metabolic syndrome is an important public health problem in Turkish people. In this review, the pathophysiology of the MS is summarized and effects of both the components and the treatment options of MS on coronary heart disease are reviewed with reference to clinical trials.
Anahtar Kelime: Metabolic Syndrome X Coronary Disease

Konular: Endokrinoloji ve Metabolizma Kalp ve Kalp Damar Sistemi
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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APA ÇAKMAK N, ÇAM N (2005). Metabolik sendrom: Önemi ve tedavisi. , 133 - 138.
Chicago ÇAKMAK Nazmiye,ÇAM NEŞE Metabolik sendrom: Önemi ve tedavisi. (2005): 133 - 138.
MLA ÇAKMAK Nazmiye,ÇAM NEŞE Metabolik sendrom: Önemi ve tedavisi. , 2005, ss.133 - 138.
AMA ÇAKMAK N,ÇAM N Metabolik sendrom: Önemi ve tedavisi. . 2005; 133 - 138.
Vancouver ÇAKMAK N,ÇAM N Metabolik sendrom: Önemi ve tedavisi. . 2005; 133 - 138.
IEEE ÇAKMAK N,ÇAM N "Metabolik sendrom: Önemi ve tedavisi." , ss.133 - 138, 2005.
ISNAD ÇAKMAK, Nazmiye - ÇAM, NEŞE. "Metabolik sendrom: Önemi ve tedavisi". (2005), 133-138.
APA ÇAKMAK N, ÇAM N (2005). Metabolik sendrom: Önemi ve tedavisi. MN Kardiyoloji, 12(2), 133 - 138.
Chicago ÇAKMAK Nazmiye,ÇAM NEŞE Metabolik sendrom: Önemi ve tedavisi. MN Kardiyoloji 12, no.2 (2005): 133 - 138.
MLA ÇAKMAK Nazmiye,ÇAM NEŞE Metabolik sendrom: Önemi ve tedavisi. MN Kardiyoloji, vol.12, no.2, 2005, ss.133 - 138.
AMA ÇAKMAK N,ÇAM N Metabolik sendrom: Önemi ve tedavisi. MN Kardiyoloji. 2005; 12(2): 133 - 138.
Vancouver ÇAKMAK N,ÇAM N Metabolik sendrom: Önemi ve tedavisi. MN Kardiyoloji. 2005; 12(2): 133 - 138.
IEEE ÇAKMAK N,ÇAM N "Metabolik sendrom: Önemi ve tedavisi." MN Kardiyoloji, 12, ss.133 - 138, 2005.
ISNAD ÇAKMAK, Nazmiye - ÇAM, NEŞE. "Metabolik sendrom: Önemi ve tedavisi". MN Kardiyoloji 12/2 (2005), 133-138.