TY  - JOUR
TI  - Comparison of four different non-invasive respiratorysupport techniques as primary respiratory support inpreterm infants
AB  - Background. The use of non-invasive ventilation methods in neonatal intensive care units has been increasingin recent years. Non-invasive ventilation techniques are lung preserving methods and they reduce the risk ofvolutrauma, barotrauma, and atelectotrauma. Methods. The effect of heated humidified high-flow nasal cannula (HHHFNC), continuous positive airwaypressure (CPAP), nasal intermittent positive-pressure ventilation (NIPPV), and nasal high-frequency oscillationventilation (NHFOV) were compared in preterm infants with respiratory distress.Results. Between December 2015 and February 2017, a total of 76 preterm infants (gestational age <32 weeks)with respiratory distress were enrolled in this study. Of the patients, 20 received HHHFNC, while 20 receivednasal CPAP (NCPAP), 19 received NIPPV, and 17 received NHFOV for respiratory support. The primaryoutcome was intubation requirement during non-invasive respiratory support. The secondary outcome includedduration of non-invasive ventilation, air leak syndrome, abdominal distension, intraventricular hemorrhage,necrotizing enterocolitis (NEC), nasal injury, increased secretions, agitation, and mortality rate. The intubationratio was higher in the NCPAP (40%) and NHFOV (29.4%) groups when compared with the NIPPV (10.5%)and HHHFNC (11.8%) groups. More nasal injury had developed in the NIPPV (78.9%) and NHFOV (82.4%)groups when compared with the NCPAP (40%) and HHHFNC (35%) groups. Moreover, the viscous secretionthat blocked the cannulas was higher in NIPPV (78.9%) and NHFOV (76.5%) groups than NCPAP (25%) andHHHFNC (40%) groups. There were no significant differences in the duration of non-invasive ventilationmethods, abdominal distension, NEC, air leak syndrome or mortality in the 4 groups.Conclusions. The NIPPV and HHHFNC methods can be useful as a primary mode of respiratory support forrespiratory distress. However, doctors need to be careful with regard to the complications that may develop.
AU  - yigit, sule
AU  - CELIK, HASAN TOLGA
AU  - Yurdakok, Murat
AU  - Öktem, Ahmet
DO  - 10.24953/turkjped.2021.01.003
PY  - 2021
JO  - Turkish Journal of Pediatrics
VL  - 63
IS  - 1
SN  - 0041-4301
SP  - 23
EP  - 30
DB  - TRDizin
UR  - http://search/yayin/detay/506767
ER  -