The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results
Yıl: 2021 Cilt: 11 Sayı: 3 Sayfa Aralığı: 241 - 248 Metin Dili: İngilizce DOI: 10.4274/jarem.galenos.2021.82473 İndeks Tarihi: 21-05-2022
The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results
Öz: Objective: It is crucial to identify the high-risk group in acute coronary syndrome (ACS) patients who underwent percutaneous coronary intervention (PCI). To date, various stratification tools have been developed to predict adverse events. However, the PR interval is a readily available parameter in routine clinical practice. This study aimed to investigate the role of the PR interval in predicting major adverse cardiovascular events (MACE) in patients with ACS who were performed PCI. Methods: Patients diagnosed with ACS and who underwent PCI between January 2015 and July 2018 were included in the study. Patients were followed up for an average of 3.2 years. Electrocardiogram was obtained from all patients on admission to the hospital. The PR interval was measured by the semi-automatic application tool. The primary outcome was all-cause mortality, new-onset decompensated heart failure, cerebrovascular event, and recurrent revascularization. Results: The mean age of total 177 ACS patients was 58.7±10.3 years and 150 (84.7%) of them were male. MACE developed in 38 patients (21.4%) who were older (p<0.001) with a male preponderance (p=0.032). The PR interval was shorter in the MACE (+) group than the MACE (-) group (154.2±21.2 vs 164.1±18.1 ms, p=0.004). Backward multivariable Cox regression analysis revealed that male gender [hazard ratio (HR)=3.667, 95% confidence interval (CI): 1.501-8.961, p=0.004], PR interval [HR=0.981, 95% CI:0.961-0.996, p=0.019], and left ventricular ejection fraction [HR=0.906, 95% CI:0.873-0.941, p<0.001] were independent predictors of MACE during long-term follow-up. Conclusion: The PR interval and male gender were independent predictors of long-term MACE in patients with ACS without atrioventricular conduction defect.
Anahtar Kelime: Primer Perkütan Koroner Girişim Uygulanan Akut Koroner Sendrom Hastalarında PR Mesafesi Majör İstenmeyen Olayları Öngörmüştür: 3 Yıllık Takip SonuçlarıPrimer Perkütan Koroner Girişim Uygulanan Akut Koroner Sendrom Hastalarında PR Mesafesi Majör İsten
Öz: Amaç: Akut koroner sendrom (AKS) hastalarında yüksek riskli grupları belirlemek önemlidir. Şimdiye kadar çeşitli sınıflandırma araçları geliştirilmiştir. PR intervali rutin günlük pratikte kolay elde edilebilir bir parametredir. Bu çalışmada perkütanöz koroner girişim (PCI) yapılmış AKS hastalarında PR mesafesinin uzun dönem majör istenmeyen advers olayları (MACE) öngörmedeki etkisini araştırmayı amaçladık. Yöntemler: Ocak 2017 ile Temmuz 2017 tarihleri arasında PCI uygulanan toplamda 177 AKS hastası çalışmaya dahil edildi. Ortalama 3,2 yıl boyunca hastalar takip edildi. Elektrokardiyografi verileri tüm hastalardan başvuru anında elde edildi ve yarı otomatik uygulama aracılığıyla PR aralıkları ölçüldü. Primer sonlanım noktası tüm sebeplere bağlı ölüm, yeni başlayan dekompanse kalp yetmezliği, serebrovasküler olay ve tekrarlayan revaskülarizasyon olarak belirlendi. Bulgular: Çalışmaya dahil edilen toplam 177 hastanın yaş ortalaması 58,7±10,3 yıl ve 150 (%84,7) kişi erkekti. Hastaların 38 tanesinde (%21,4) MACE gelişti ve bu grupta erkek cinsiyeti hakimiyeti olmakla beraber (p=0,032) daha yaşlı olduğu görüldü (p<0,001). PR intervali MACE (+) grubunda MACE (-) grubuna göre daha kısaydı (154,2±21,2 vs 164,1±18,1, p=0,004). Cox regresyon analizinde erkek cinsiyet [risk oranı (RO)=3,667, %95 güven aralığı (GA): 1,501-8,961, p=0,004], PR mesafesi [RO=0,981, 95% GA:0,961-0,996, p=0,019] ve sol ventrikül ejeksiyon fraksiyonu [RO=0,906, %95 GA: 0,873- 0,941, p<0,001] bağımsız MACE öngördürücüsüydü. Sonuç: Atriyoventriküler ileti kusuru olmayan AKS hastalarında PR mesafesi ve erkek cinsiyet uzun dönem istenmeyen olayların bağımsız öngördürücüsüdür.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Yilmaz A, Çinier G, Kahraman F, Çetin M, Çırakoğlu Ö (2021). The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. , 241 - 248. 10.4274/jarem.galenos.2021.82473 |
| Chicago | Yilmaz Ahmet Seyda,Çinier Göksel,Kahraman Fatih,Çetin Mustafa,Çırakoğlu Ömer Faruk The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. (2021): 241 - 248. 10.4274/jarem.galenos.2021.82473 |
| MLA | Yilmaz Ahmet Seyda,Çinier Göksel,Kahraman Fatih,Çetin Mustafa,Çırakoğlu Ömer Faruk The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. , 2021, ss.241 - 248. 10.4274/jarem.galenos.2021.82473 |
| AMA | Yilmaz A,Çinier G,Kahraman F,Çetin M,Çırakoğlu Ö The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. . 2021; 241 - 248. 10.4274/jarem.galenos.2021.82473 |
| Vancouver | Yilmaz A,Çinier G,Kahraman F,Çetin M,Çırakoğlu Ö The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. . 2021; 241 - 248. 10.4274/jarem.galenos.2021.82473 |
| IEEE | Yilmaz A,Çinier G,Kahraman F,Çetin M,Çırakoğlu Ö "The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results." , ss.241 - 248, 2021. 10.4274/jarem.galenos.2021.82473 |
| ISNAD | Yilmaz, Ahmet Seyda vd. "The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results". (2021), 241-248. https://doi.org/10.4274/jarem.galenos.2021.82473 |
| APA | Yilmaz A, Çinier G, Kahraman F, Çetin M, Çırakoğlu Ö (2021). The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. JAREM, 11(3), 241 - 248. 10.4274/jarem.galenos.2021.82473 |
| Chicago | Yilmaz Ahmet Seyda,Çinier Göksel,Kahraman Fatih,Çetin Mustafa,Çırakoğlu Ömer Faruk The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. JAREM 11, no.3 (2021): 241 - 248. 10.4274/jarem.galenos.2021.82473 |
| MLA | Yilmaz Ahmet Seyda,Çinier Göksel,Kahraman Fatih,Çetin Mustafa,Çırakoğlu Ömer Faruk The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. JAREM, vol.11, no.3, 2021, ss.241 - 248. 10.4274/jarem.galenos.2021.82473 |
| AMA | Yilmaz A,Çinier G,Kahraman F,Çetin M,Çırakoğlu Ö The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. JAREM. 2021; 11(3): 241 - 248. 10.4274/jarem.galenos.2021.82473 |
| Vancouver | Yilmaz A,Çinier G,Kahraman F,Çetin M,Çırakoğlu Ö The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results. JAREM. 2021; 11(3): 241 - 248. 10.4274/jarem.galenos.2021.82473 |
| IEEE | Yilmaz A,Çinier G,Kahraman F,Çetin M,Çırakoğlu Ö "The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results." JAREM, 11, ss.241 - 248, 2021. 10.4274/jarem.galenos.2021.82473 |
| ISNAD | Yilmaz, Ahmet Seyda vd. "The PR Interval Predicted Major Adverse Cardiovascular Events in Patients with Acute Coronary Syndrome Who Underwent Percutaneous Coronary Intervention: 3 Years Follow-up Results". JAREM 11/3 (2021), 241-248. https://doi.org/10.4274/jarem.galenos.2021.82473 |
