Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer
Yıl: 2021 Cilt: 20 Sayı: 2 Sayfa Aralığı: 111 - 116 Metin Dili: İngilizce DOI: 10.4274/uob.galenos.2020.1885 İndeks Tarihi: 21-05-2022
Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer
Öz: Objective: Estimating surgical complications is crucial to assess the benefit-harm balance of partial nephrectomy (PN), a complex surgical option compared to radical nephrectomy. This study aimed to assess the factors affecting the occurrence of modified Clavien-Dindo grade 2 or higher complications after PN. Materials and Methods: Data of patients who underwent PN due to renal cancer from January 2015 to June 2018 were prospectively collected. Database was analysed retrospectively by dividing into two groups with Clavien-Dindo grade 0-1 complications (group 1) and with grade 2 or higher complications (group 2). The resection technique was classified by the surgeon as enucleation, enucleo-resection or resection according to the Surface-Intermediate-Base (SIB) margin scores of 0, 1 and 2, respectively. Factors affecting the occurrence of grade 2 or higher complications were evaluated by univariate and multivariate regression analysis. Results: A total of 161 patients were included in the study. The overall rate of perioperative complications was 18.6%. Twenty-four patients (14.9%) had grade 2 or higher complications and 11 patients (6.8%) had serious complications (grade 3 or higher). SIB-score was 0 in 103 (63.9%) patients, 1 in 36 (22.4%) patients and 2 in 22 (13.7%) patients. Multivariate binary logistic regression analysis revealed that the C-index [odds ratio (OR): 0.224, 95% confidence interval (CI): 0.092- 0.493, p=0.001], laparoscopic surgical technique (OR: 12.668, 95% CI: 2.825-59.326, p=0.001), and SIB-score 1-2 (OR: 2.852, 95% CI: 1.416-9.826, p=0.002) are independent factors in predicting complications of Clavien-Dindo grade 2 or higher. Conclusion: C-index, laparoscopic approach and resection techniques (SIB-score 1-2) are independent factors in predicting perioperative complications of ClavienDindo grade 2 or higher following PN.
Anahtar Kelime: Perioperatif Anlamlı Öngörü Faktörleri Böbrek İçin Kısmi Nefrektomi Sonrası Komplikasyonlar Hücre Kanseri
Öz: Amaç: Radikal cerrahiye kıyasla karmaşık bir cerrahi seçenek olan parsiyel nefrektominin (PN) yarar-zarar dengesini değerlendirmek için cerrahi komplikasyonları tahmin etmek çok önemlidir. nefrektomi. Bu çalışma, PN sonrası modifiye Clavien-Dindo derece 2 veya daha yüksek komplikasyonların oluşumunu etkileyen faktörleri değerlendirmeyi amaçladı. Gereç ve Yöntem: Ocak 2015 ile Haziran 2018 tarihleri arasında böbrek kanseri nedeniyle PN uygulanan hastaların verileri prospektif olarak toplandı. Veritabanı (önceki değeri) Clavien-Dindo derece 0-1 komplikasyonları olan (grup 1) ve derece 2 veya daha yüksek komplikasyonları olan (grup 2) iki gruba ayrılarak retrospektif olarak analiz edildi. bu rezeksiyon tekniği, cerrah tarafından Yüzey-Orta-Taban (SIB) marj skorlarına göre enükleasyon, enükleo-rezeksiyon veya rezeksiyon olarak sınıflandırıldı. sırasıyla 0, 1 ve 2'dir. Derece 2 veya daha yüksek komplikasyonların oluşumunu etkileyen faktörler, tek değişkenli ve çok değişkenli regresyon analizi ile değerlendirildi. Bulgular: Çalışmaya toplam 161 hasta dahil edildi. Genel perioperatif komplikasyon oranı %18,6 idi. Yirmi dört hastada (%14.9) derece 2 vardı. veya daha yüksek komplikasyonlar ve 11 hastada (%6,8) ciddi komplikasyonlar (grade 3 veya üstü) vardı. SIB skoru 103 (%63.9) hastada 0, 36 (%22.4) hastada 1 idi. ve 22 hastada 2 (%13,7). Çok değişkenli ikili lojistik regresyon analizi, C-endeksi [olasılık oranı (OR): 0.224, %95 güven aralığı (GA): 0.092- 0.493, p=0.001], laparoskopik cerrahi teknik (OR: 12.668, %95 GA: 2.825-59.326, p=0.001) ve SIB skoru 1-2 (OR: 2.852, %95 GA: 1.416-9.826, p= 0.002) Clavien-Dindo derece 2 veya daha yüksek komplikasyonları öngörmede bağımsız faktörler. Sonuç: C-index, laparoskopik yaklaşım ve rezeksiyon teknikleri (SIB skoru 1-2), PN sonrası ClavienDindo derece 2 veya daha yüksek perioperatif komplikasyonları öngörmede bağımsız faktörlerdir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Çakıcı M, Karakoyunlu N, Kokurcan A, ÖZENÇ G, SARI S, Hepşen E, yalcinkaya f (2021). Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. , 111 - 116. 10.4274/uob.galenos.2020.1885 |
| Chicago | Çakıcı Mehmet Çağlar,Karakoyunlu Nihat,Kokurcan Alihan,ÖZENÇ GÖRKEM,SARI SERCAN,Hepşen Emre,yalcinkaya fatih Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. (2021): 111 - 116. 10.4274/uob.galenos.2020.1885 |
| MLA | Çakıcı Mehmet Çağlar,Karakoyunlu Nihat,Kokurcan Alihan,ÖZENÇ GÖRKEM,SARI SERCAN,Hepşen Emre,yalcinkaya fatih Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. , 2021, ss.111 - 116. 10.4274/uob.galenos.2020.1885 |
| AMA | Çakıcı M,Karakoyunlu N,Kokurcan A,ÖZENÇ G,SARI S,Hepşen E,yalcinkaya f Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. . 2021; 111 - 116. 10.4274/uob.galenos.2020.1885 |
| Vancouver | Çakıcı M,Karakoyunlu N,Kokurcan A,ÖZENÇ G,SARI S,Hepşen E,yalcinkaya f Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. . 2021; 111 - 116. 10.4274/uob.galenos.2020.1885 |
| IEEE | Çakıcı M,Karakoyunlu N,Kokurcan A,ÖZENÇ G,SARI S,Hepşen E,yalcinkaya f "Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer." , ss.111 - 116, 2021. 10.4274/uob.galenos.2020.1885 |
| ISNAD | Çakıcı, Mehmet Çağlar vd. "Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer". (2021), 111-116. https://doi.org/10.4274/uob.galenos.2020.1885 |
| APA | Çakıcı M, Karakoyunlu N, Kokurcan A, ÖZENÇ G, SARI S, Hepşen E, yalcinkaya f (2021). Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. Üroonkoloji Bülteni, 20(2), 111 - 116. 10.4274/uob.galenos.2020.1885 |
| Chicago | Çakıcı Mehmet Çağlar,Karakoyunlu Nihat,Kokurcan Alihan,ÖZENÇ GÖRKEM,SARI SERCAN,Hepşen Emre,yalcinkaya fatih Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. Üroonkoloji Bülteni 20, no.2 (2021): 111 - 116. 10.4274/uob.galenos.2020.1885 |
| MLA | Çakıcı Mehmet Çağlar,Karakoyunlu Nihat,Kokurcan Alihan,ÖZENÇ GÖRKEM,SARI SERCAN,Hepşen Emre,yalcinkaya fatih Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. Üroonkoloji Bülteni, vol.20, no.2, 2021, ss.111 - 116. 10.4274/uob.galenos.2020.1885 |
| AMA | Çakıcı M,Karakoyunlu N,Kokurcan A,ÖZENÇ G,SARI S,Hepşen E,yalcinkaya f Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. Üroonkoloji Bülteni. 2021; 20(2): 111 - 116. 10.4274/uob.galenos.2020.1885 |
| Vancouver | Çakıcı M,Karakoyunlu N,Kokurcan A,ÖZENÇ G,SARI S,Hepşen E,yalcinkaya f Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer. Üroonkoloji Bülteni. 2021; 20(2): 111 - 116. 10.4274/uob.galenos.2020.1885 |
| IEEE | Çakıcı M,Karakoyunlu N,Kokurcan A,ÖZENÇ G,SARI S,Hepşen E,yalcinkaya f "Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer." Üroonkoloji Bülteni, 20, ss.111 - 116, 2021. 10.4274/uob.galenos.2020.1885 |
| ISNAD | Çakıcı, Mehmet Çağlar vd. "Predictive Factors of Perioperative Significant Complications Following Partial Nephrectomy for Renal Cell Cancer". Üroonkoloji Bülteni 20/2 (2021), 111-116. https://doi.org/10.4274/uob.galenos.2020.1885 |
