Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial

Öz:

Objectives: To describe the prevalence of risk factors in patients infected with hepatitis C virus (HCV). Materials and Methods: Patients who were aged >18 years visiting outpatient clinics and diagnosed as having HCV infection were enrolled in this cross-sectional, multicenter study conducted in 71 cities. Patient data on socio-demographic and clinical characteristics and pre-defined risk factors were collected. Results: Among 1,018 patients, 53.0% were women. The mean age was 57.2±14.3 years and 34.8% had been diagnosed as having HCV infection >10 years before enrollment. Almost half of the patients (45.5%) were diagnosed during their regular check-up visits, and only 16.8% were diagnosed because of signs or symptoms of HCV. Genotype 1 and sub-genotype 1 b were detected in 87.9% and 73.7% of the patients, respectively. At least one risk factor was present in 94.8% of the patients. The most frequently reported risk factor was major dental procedures (79.2%), followed by major surgical operations (56.9%) and minor surgical interventions (42.3%). Conclusion: Our results revealed that most of the patients with HCV infection underwent major dental procedures

Anahtar Kelime:

Türkiye’de Hepatit C Hastalarının Demografik Karakteristikleri ve Bulaşma Risk Faktörleri: Çok Merkezli ve Kesitsel EPI-C Çalışması

Öz:

Amaç: Bu çalışmanın amacı hepatit C virüsü (HCV) ile enfekte hastalarda risk faktörlerinin prevalansını belirlemektir. Gereç ve Yöntemler: Poliklinik ziyaretlerinde HCV tanısı almış, 18 yaşından büyük hastalar, 71 farklı ilde yürütülmüş olan bu çok merkezli, kesitsel çalışmaya dahil edilmiştir. Hastaların sosyodemografik ve klinik karakteristikleri ile önceden belirlenmiş olan risk faktörleri ile ilgili veriler toplanmıştır. Bulgular: Bu çalışmaya dahil edilen toplam 1.018 hastanın %53,0’ı kadındı. Ortalama yaş 57,2±14,3 yıl idi ve hastaların %34,8’i için HCV enfeksiyonu tanı süresi >10 yıl idi. Hastaların neredeyse yarısı (%45,5) rutin check-up sırasında teşhis edildi ve sadece %16,8’i HCV ile ilişkili bir belirti veya semptom nedeniyle teşhis edildi. Olguların %87,9 ve %73,7’sinde sırasıyla genotip 1 ve alt genotip 1-b tespit edildi. Hastaların %94,8’inde en az bir risk faktörü mevcuttu. En sık bildirilen risk faktörü majör dental işlemler (%79,2) idi, bunu %56,9’luk oranla majör cerrahi operasyonlar ve %42,3’lük oranla minör cerrahi müdahaleler izledi. Sonuç: Sonuçlarımız, HCV enfeksiyonu olan hastaların çoğunun majör dental işlemler gördüğünü göstermektedir

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Tabak F, Sirin G, DEMIR M, Aladag M, Sumer S, Kurtaran B, Tosun S, YAMAZHAN T, bozkurt i, Gürbüz Y, Batirel A, Şenateş E, KANDEMİR F, TOPAL F, DOGANAY H, Sezgin O, mıstık r, köse ş, Yilmaz Y, İNAN D, Koksal I, PARLAK E, Akdogan M, GÜNER R (2021). Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. , 109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
Chicago	Tabak Fehmi,Sirin Goktug,DEMIR MEHMET,Aladag Murat,Sumer Sua,Kurtaran Behice,Tosun Selma,YAMAZHAN Tansu,bozkurt ilkay,Gürbüz Yunus,Batirel Ayse,Şenateş Ebubekir,KANDEMİR Fatma Özlem,TOPAL FIRDEVS,DOGANAY HAMDI LEVENT,Sezgin Orhan,mıstık reşit,köse şükran,Yilmaz Yusuf,İNAN DİLARA,Koksal Iftihar,PARLAK EMINE,Akdogan Meral,GÜNER RAHMET Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. (2021): 109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
MLA	Tabak Fehmi,Sirin Goktug,DEMIR MEHMET,Aladag Murat,Sumer Sua,Kurtaran Behice,Tosun Selma,YAMAZHAN Tansu,bozkurt ilkay,Gürbüz Yunus,Batirel Ayse,Şenateş Ebubekir,KANDEMİR Fatma Özlem,TOPAL FIRDEVS,DOGANAY HAMDI LEVENT,Sezgin Orhan,mıstık reşit,köse şükran,Yilmaz Yusuf,İNAN DİLARA,Koksal Iftihar,PARLAK EMINE,Akdogan Meral,GÜNER RAHMET Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. , 2021, ss.109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
AMA	Tabak F,Sirin G,DEMIR M,Aladag M,Sumer S,Kurtaran B,Tosun S,YAMAZHAN T,bozkurt i,Gürbüz Y,Batirel A,Şenateş E,KANDEMİR F,TOPAL F,DOGANAY H,Sezgin O,mıstık r,köse ş,Yilmaz Y,İNAN D,Koksal I,PARLAK E,Akdogan M,GÜNER R Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. . 2021; 109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
Vancouver	Tabak F,Sirin G,DEMIR M,Aladag M,Sumer S,Kurtaran B,Tosun S,YAMAZHAN T,bozkurt i,Gürbüz Y,Batirel A,Şenateş E,KANDEMİR F,TOPAL F,DOGANAY H,Sezgin O,mıstık r,köse ş,Yilmaz Y,İNAN D,Koksal I,PARLAK E,Akdogan M,GÜNER R Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. . 2021; 109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
IEEE	Tabak F,Sirin G,DEMIR M,Aladag M,Sumer S,Kurtaran B,Tosun S,YAMAZHAN T,bozkurt i,Gürbüz Y,Batirel A,Şenateş E,KANDEMİR F,TOPAL F,DOGANAY H,Sezgin O,mıstık r,köse ş,Yilmaz Y,İNAN D,Koksal I,PARLAK E,Akdogan M,GÜNER R "Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial." , ss.109 - 117, 2021. 10.4274/vhd.galenos.2021.2021-1-3
ISNAD	Tabak, Fehmi vd. "Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial". (2021), 109-117. https://doi.org/10.4274/vhd.galenos.2021.2021-1-3

APA	Tabak F, Sirin G, DEMIR M, Aladag M, Sumer S, Kurtaran B, Tosun S, YAMAZHAN T, bozkurt i, Gürbüz Y, Batirel A, Şenateş E, KANDEMİR F, TOPAL F, DOGANAY H, Sezgin O, mıstık r, köse ş, Yilmaz Y, İNAN D, Koksal I, PARLAK E, Akdogan M, GÜNER R (2021). Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. Viral Hepatitis Journal, 27(3), 109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
Chicago	Tabak Fehmi,Sirin Goktug,DEMIR MEHMET,Aladag Murat,Sumer Sua,Kurtaran Behice,Tosun Selma,YAMAZHAN Tansu,bozkurt ilkay,Gürbüz Yunus,Batirel Ayse,Şenateş Ebubekir,KANDEMİR Fatma Özlem,TOPAL FIRDEVS,DOGANAY HAMDI LEVENT,Sezgin Orhan,mıstık reşit,köse şükran,Yilmaz Yusuf,İNAN DİLARA,Koksal Iftihar,PARLAK EMINE,Akdogan Meral,GÜNER RAHMET Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. Viral Hepatitis Journal 27, no.3 (2021): 109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
MLA	Tabak Fehmi,Sirin Goktug,DEMIR MEHMET,Aladag Murat,Sumer Sua,Kurtaran Behice,Tosun Selma,YAMAZHAN Tansu,bozkurt ilkay,Gürbüz Yunus,Batirel Ayse,Şenateş Ebubekir,KANDEMİR Fatma Özlem,TOPAL FIRDEVS,DOGANAY HAMDI LEVENT,Sezgin Orhan,mıstık reşit,köse şükran,Yilmaz Yusuf,İNAN DİLARA,Koksal Iftihar,PARLAK EMINE,Akdogan Meral,GÜNER RAHMET Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. Viral Hepatitis Journal, vol.27, no.3, 2021, ss.109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
AMA	Tabak F,Sirin G,DEMIR M,Aladag M,Sumer S,Kurtaran B,Tosun S,YAMAZHAN T,bozkurt i,Gürbüz Y,Batirel A,Şenateş E,KANDEMİR F,TOPAL F,DOGANAY H,Sezgin O,mıstık r,köse ş,Yilmaz Y,İNAN D,Koksal I,PARLAK E,Akdogan M,GÜNER R Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. Viral Hepatitis Journal. 2021; 27(3): 109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
Vancouver	Tabak F,Sirin G,DEMIR M,Aladag M,Sumer S,Kurtaran B,Tosun S,YAMAZHAN T,bozkurt i,Gürbüz Y,Batirel A,Şenateş E,KANDEMİR F,TOPAL F,DOGANAY H,Sezgin O,mıstık r,köse ş,Yilmaz Y,İNAN D,Koksal I,PARLAK E,Akdogan M,GÜNER R Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial. Viral Hepatitis Journal. 2021; 27(3): 109 - 117. 10.4274/vhd.galenos.2021.2021-1-3
IEEE	Tabak F,Sirin G,DEMIR M,Aladag M,Sumer S,Kurtaran B,Tosun S,YAMAZHAN T,bozkurt i,Gürbüz Y,Batirel A,Şenateş E,KANDEMİR F,TOPAL F,DOGANAY H,Sezgin O,mıstık r,köse ş,Yilmaz Y,İNAN D,Koksal I,PARLAK E,Akdogan M,GÜNER R "Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial." Viral Hepatitis Journal, 27, ss.109 - 117, 2021. 10.4274/vhd.galenos.2021.2021-1-3
ISNAD	Tabak, Fehmi vd. "Demographic Characteristics and Transmission Risk Factors of Patients with Hepatitis C Virus in Turkey: The EPI-C, A Multicenter and Cross-sectional Trial". Viral Hepatitis Journal 27/3 (2021), 109-117. https://doi.org/10.4274/vhd.galenos.2021.2021-1-3