TY  - JOUR
TI  - Convalescent Plasma Reduces Endogenous Antibody Response in
COVID-19: A Retrospective Cross-Sectional Study
AB  - Objective: The aim of this study is to investigate post-COVID-19
antibody titers in patients who received convalescent plasma (CP) in
addition to standard-of-care treatment.
Materials and Methods: Hospitalized COVID-19 patients who received
CP in addition to standard care were retrospectively investigated.
Patients who received CP with a recorded total COVID-19 antibody
test result after treatment were included. From among hospitalized
COVID-19 patients who received only standard care with a recorded
total COVID-19 antibody test result, a control group matched for age,
gender, and comorbidities was formed. Total COVID-19 antibody index
levels were compared.
Results: Thirty-three CP recipients were enrolled in the study. The
control group consisted of 34 age-, gender-, and comorbiditymatched
standard-care patients. Median total COVID-19 antibody
index levels were significantly reduced in the CP group.
Conclusion: Although CP therapy may have benefits for disease
outcome, its potential ability to hamper long-term immunity may be
a problem.
AU  - ERDEN, Abdulsamet
AU  - ateş, ihsan
AU  - Güven, Serdar Can
AU  - Omma, Ahmet
AU  - KÜÇÜKŞAHİN, Orhan
DO  - 10.4274/tjh.galenos.2021.2021.0277
PY  - 2021
JO  - Turkish Journal of Hematology
VL  - 38
IS  - 4
SN  - 1300-7777
SP  - 321
EP  - 324
DB  - TRDizin
UR  - http://search/yayin/detay/508861
ER  -