TY  - JOUR
TI  - Evaluation of the Association between Paranasal Sinus 
Osteomas and Anatomic Variations Using Computed 
Tomography
AB  - Objective: The pathogenesis of paranasal sinus osteoma (PSO) has not been fully elucidated. It is 
thought that both embryological and developmental factors play a role in the etiology. The aim of 
the present study was to investigate the association of frequency and localization of PSOs detected 
on computed tomography (CT) examination with osteoma presence. 
Methods: In this retrospective study conducted in December 2017 through March 2020 in 
Gaziosmanpaşa University Faculty of Medicine, images of a total of 18,867 patients who 
underwent paranasal sinus, maxillofacial CT and brain CT angiography were reviewed for 
the presence of PSOs. Sizes of PSOs and accompanying mucosal pathologies were identified. 
Associations between PSOs and paranasal sinus variations were evaluated statistically compared 
to the control group (200 patients without PSO).
Results: A total of 176 patients (0.92%) were found to have PSO. Average age of the patients with 
PSO was 59.9 years (range: 18–93). PSOs were unilateral in 152 patients while 24 patients had 
multiple osteomas. Female/male ratio was 1.1/1. PSOs were most commonly located in the frontal 
sinuses. Frequencies of vertical concha bullosa, secondary middle turbinate, twisted uncinate, 
supraorbital ethmoid cell, intersinus septal cell, ethmoidomaxillary cell, Haller’s cell, frontal sinus 
hypoplasia and sphenoid sinus hypoplasia were significantly higher in the patient group compared 
to the control group.
Conclusion: Higher or lower incidence rates of some anatomic variations in the patients with 
PSO could be explained by the possible effects of genetic and/or environmental factor. Additional 
studies are needed to evaluate these possible associations.
AU  - Beyhan, Murat
AU  - aksakal, ceyhun
AU  - Gökçe, Erkan
DO  - 10.4274/tao.2020.5811
PY  - 2021
JO  - Turkish archives of otorhinolaryngology 
VL  - 59
IS  - 1
SN  - 2667-7466
SP  - 54
EP  - 64
DB  - TRDizin
UR  - http://search/yayin/detay/509240
ER  -