TY  - JOUR
TI  - Synthesis, Cyclization and Nucleophilic Substitution Reactions of Substituted Pyrazole Carboxylic Acid
AB  - Substituted pyrazole carboxylic acid 2a-b derivatives, obtained from 2,3-furandione 1 and benzaldehyde hydrazone 11a-b was converted via reactions of its acid chloride 3a-b. The corresponding ester 6a-b, urea 7a-b, and amide derivatives 4a-b, 8a-b were obtained from the reaction of the acyl chloride of the pyrazole carboxylic acid with various alcohols, urea, and amines. Additionally, the corresponding nitrile derivatives 5 were obtained by extracting water from the amide derivatives (SOCl2 / DMF). Furthermore, cyclization reactions of substituted pyrazole carboxylic acid derivatives using hydrazine were investigated 9 and reaction of 2b decarboxylation product 10.
AU  - Güner ÇELİK, Aycan
AU  - TOZLU, İsrafil
AU  - TASDEMIR, VOLKAN
AU  - genç, hasan
DO  - 10.21597/jist.948269
PY  - 2022
JO  - Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
VL  - 12
IS  - 1
SN  - 2146-0574
SP  - 279
EP  - 286
DB  - TRDizin
UR  - http://search/yayin/detay/509880
ER  -