Yıl: 2004 Cilt: 33 Sayı: 1 Sayfa Aralığı: 7 - 9 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS

Öz:
Bu çalışmada, Köprübaşı (Diyarbakır-Türkiye) den toplanan Heliotropium europaeum L. bitkisinin tohumlarından elde edilen alkaloit ekstresi GC-MS ile analiz edilmiştir. Tohumlarda total pirolizidin alkaloidi miktarı % 0.28, tersiyer bazların miktarı ise % 0.02 olarak bulunmuştur. Total alkaloit miktarının % 92.86 sini N-oksitleri oluşturmaktadır. Total alkaloit ve tersiyer baz fraksiyonlarındaki alkaloitler europin, heliotrin, supinin, heleurin, lasiokarpin ve 7-angelilheliotrin olarak teşhis edilmiştir.
Anahtar Kelime: Tohumlar Diyarbakır Pirolizidin alkaloidleri Türkiye Heliotropium

Konular: Farmakoloji ve Eczacılık

Heliotropium europaeum tohumlarında GC-MS ile pirolizidin alkaloitlerinin tayini

Öz:
In the current research, alkaloid extract obtained from the seeds of Heliotropium europaeum L. collected from Köprübaşı (Diyarbakır, Turkey) was analysed by using GC-MS method. The total pyrrolizidine alkaloid and tertiary base content of the seeds of Heliotropium europaeum were found to be 0.28 % and 0.02 % respectively. Higher percentage of alkaloids were present as N-oxides (92.86 % of the alkaloids). Alkaloids found in the tertiary base fraction and total alkaloid fraction were identified as europine, heliotrine, supinine, heleurine, lasiocarpine and 7-angelylheliotrine
Anahtar Kelime: Pyrrolizidine Alkaloids Turkey Heliotropium Seeds Diyarbakır

Konular: Farmakoloji ve Eczacılık
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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  • 4. Culvenor, C. C. J., “Alkaloids of Heliotropium europaeum. II Isolation and structures of the third major alkaloid and two minor alkaloids and isolations of the principal Noxides”. Aust. J. Chem. 7: 287-297 (1954). C.A., 49, 8999h, 1955.
APA Tosun F, Tamer U (2004). Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. , 7 - 9.
Chicago Tosun Fatma,Tamer Ugur Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. (2004): 7 - 9.
MLA Tosun Fatma,Tamer Ugur Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. , 2004, ss.7 - 9.
AMA Tosun F,Tamer U Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. . 2004; 7 - 9.
Vancouver Tosun F,Tamer U Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. . 2004; 7 - 9.
IEEE Tosun F,Tamer U "Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS." , ss.7 - 9, 2004.
ISNAD Tosun, Fatma - Tamer, Ugur. "Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS". (2004), 7-9.
APA Tosun F, Tamer U (2004). Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. Ankara Üniversitesi Eczacılık Fakültesi Dergisi, 33(1), 7 - 9.
Chicago Tosun Fatma,Tamer Ugur Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. Ankara Üniversitesi Eczacılık Fakültesi Dergisi 33, no.1 (2004): 7 - 9.
MLA Tosun Fatma,Tamer Ugur Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. Ankara Üniversitesi Eczacılık Fakültesi Dergisi, vol.33, no.1, 2004, ss.7 - 9.
AMA Tosun F,Tamer U Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. Ankara Üniversitesi Eczacılık Fakültesi Dergisi. 2004; 33(1): 7 - 9.
Vancouver Tosun F,Tamer U Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS. Ankara Üniversitesi Eczacılık Fakültesi Dergisi. 2004; 33(1): 7 - 9.
IEEE Tosun F,Tamer U "Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS." Ankara Üniversitesi Eczacılık Fakültesi Dergisi, 33, ss.7 - 9, 2004.
ISNAD Tosun, Fatma - Tamer, Ugur. "Determination of pyrrolizidine alkaloids in the seeds of Heliotropium europaeum by GC-MS". Ankara Üniversitesi Eczacılık Fakültesi Dergisi 33/1 (2004), 7-9.