Dosimetric Comparison of Intensity-Modulated Radiation
Therapy and Volumetric Modulated Arc Therapy in
Craniospinal Radiotherapy of Childhood

Uzel, Ömer; Karacam, Songul; Çoban, Yasin; çifter, fulya; Ozer, elif eda

doi:10.5505/tjo.2020.2381

Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood

Elif Eda OZER, (Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)

Yasin ÇOBAN, (İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)

Fulya ÇİFTER, (Radyasyon Onkolojisi Anabilim Dalı, Precision Medical Derivatives Inc, Short Hills, New Jersey, ABD)

Songül ÇAVDAR KARAÇAM, (İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)

Ömer Erol UZEL (İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)

Türk Onkoloji Dergisi

5 1

Yıl: 2021 Cilt: 36 Sayı: 1 Sayfa Aralığı: 96 - 103 Metin Dili: İngilizce DOI: 10.5505/tjo.2020.2381 İndeks Tarihi: 27-05-2022

Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood

Öz:

OBJECTIVE Central nervous system (CNS) tumors are the most common solid organ tumors in children. We aimed to compare two modern radiotherapy techniques in target volumes and doses received by organs at risk (OAR). METHODS Eleven patients who had undergone 3D conformal radiotherapy (3DCRT) with the indication of craniospinal radiation therapy (CSRT) were included. OAR and target volumes were defined. The planned target volume (PTV) was PTV of the brain and PTV of the entire spine. A total of 36 Gy at 1,8 Gy/fraction was given to all patients. Intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) plans were prepared. RESULTS At mean doses of optic nerve, thyroid, esophagus, heart and oral cavity; VMAT was significantly superior to IMRT. At mean doses of lungs and kidneys; IMRT was better than VMAT. Dmax of VMAT was at lower limits for all OAR. Regarding low doses received by the body, IMRT was better in V2 and V5; while VMAT was better in V15 and V20. For PTV, V95 was 99% and 97%, and V107 was 2.6% and 4% in IMRT and VMAT, respectively. Regarding monitor units (MU), VMAT revealed significantly lower MU than IMRT. CONCLUSION Two techniques are suitable treatment choices for CSRT and may be utilized to diminish the late adverse effects of radiation and to increase disease-free survival rates in patients receiving CSRT. Nevertheless, the risk of secondary cancer development should be kept in mind

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Ozer e, Çoban Y, çifter f, Karacam S, Uzel Ö (2021). Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. , 96 - 103. 10.5505/tjo.2020.2381
Chicago	Ozer elif eda,Çoban Yasin,çifter fulya,Karacam Songul,Uzel Ömer Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. (2021): 96 - 103. 10.5505/tjo.2020.2381
MLA	Ozer elif eda,Çoban Yasin,çifter fulya,Karacam Songul,Uzel Ömer Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. , 2021, ss.96 - 103. 10.5505/tjo.2020.2381
AMA	Ozer e,Çoban Y,çifter f,Karacam S,Uzel Ö Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. . 2021; 96 - 103. 10.5505/tjo.2020.2381
Vancouver	Ozer e,Çoban Y,çifter f,Karacam S,Uzel Ö Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. . 2021; 96 - 103. 10.5505/tjo.2020.2381
IEEE	Ozer e,Çoban Y,çifter f,Karacam S,Uzel Ö "Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood." , ss.96 - 103, 2021. 10.5505/tjo.2020.2381
ISNAD	Ozer, elif eda vd. "Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood". (2021), 96-103. https://doi.org/10.5505/tjo.2020.2381

APA	Ozer e, Çoban Y, çifter f, Karacam S, Uzel Ö (2021). Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. Türk Onkoloji Dergisi, 36(1), 96 - 103. 10.5505/tjo.2020.2381
Chicago	Ozer elif eda,Çoban Yasin,çifter fulya,Karacam Songul,Uzel Ömer Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. Türk Onkoloji Dergisi 36, no.1 (2021): 96 - 103. 10.5505/tjo.2020.2381
MLA	Ozer elif eda,Çoban Yasin,çifter fulya,Karacam Songul,Uzel Ömer Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. Türk Onkoloji Dergisi, vol.36, no.1, 2021, ss.96 - 103. 10.5505/tjo.2020.2381
AMA	Ozer e,Çoban Y,çifter f,Karacam S,Uzel Ö Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. Türk Onkoloji Dergisi. 2021; 36(1): 96 - 103. 10.5505/tjo.2020.2381
Vancouver	Ozer e,Çoban Y,çifter f,Karacam S,Uzel Ö Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood. Türk Onkoloji Dergisi. 2021; 36(1): 96 - 103. 10.5505/tjo.2020.2381
IEEE	Ozer e,Çoban Y,çifter f,Karacam S,Uzel Ö "Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood." Türk Onkoloji Dergisi, 36, ss.96 - 103, 2021. 10.5505/tjo.2020.2381
ISNAD	Ozer, elif eda vd. "Dosimetric Comparison of Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy in Craniospinal Radiotherapy of Childhood". Türk Onkoloji Dergisi 36/1 (2021), 96-103. https://doi.org/10.5505/tjo.2020.2381